Ephrin B2 antibody

Catalog No. ABIN966079

Product Details anti-Ephrin B2 Antibody

Target: Ephrin B2 (EFNB2)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ephrin B2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Specificity: Ephrin-B2 (Ab-330) antibody detects endogenous levels of total Ephrin-B2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human Ephrin-B2 around the phosphorylation site of tyrosine 330 (N-I-YP-Y-K).

Application Details

Application Notes: WB: 1:500~1:1000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-Ephrin B2 antibody (ABIN966079)

Chrencik, Brooun, Kraus, Recht, Kolatkar, Han, Seifert, Widmer, Auer, Kuhn: "Structural and biophysical characterization of the EphB4*ephrinB2 protein-protein interaction and receptor specificity." in: The Journal of biological chemistry, Vol. 281, Issue 38, pp. 28185-92, (2006) (PubMed).

Kertesz, Krasnoperov, Reddy, Leshanski, Kumar, Zozulya, Gill: "The soluble extracellular domain of EphB4 (sEphB4) antagonizes EphB4-EphrinB2 interaction, modulates angiogenesis, and inhibits tumor growth." in: Blood, Vol. 107, Issue 6, pp. 2330-8, (2006) (PubMed).

Noren, Lu, Freeman, Koolpe, Pasquale: "Interplay between EphB4 on tumor cells and vascular ephrin-B2 regulates tumor growth." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 15, pp. 5583-8, (2004) (PubMed).

Target Details for Ephrin B2

Target: Ephrin B2 (EFNB2)

Alternative Name: Ephrin-B2 (EFNB2 Products)

Synonyms: EFNB2 antibody, efnb2 antibody, ephrin-B2 antibody, htkl antibody, eplg5 antibody, htk-l antibody, lerk5 antibody, ephrinB2 antibody, efnb2a antibody, MGC68890 antibody, efnb2b antibody, ELF-2 antibody, Epl5 antibody, Eplg5 antibody, Htk-L antibody, LERK-5 antibody, Lerk5 antibody, NLERK-1 antibody, EPLG5 antibody, HTKL antibody, LERK5 antibody, ephrin B2 antibody, ephrin-B2 precursor antibody, ephrin B2 L homeolog antibody, ephrin B2 S homeolog antibody, EFNB2 antibody, efnb2 antibody, efnb2.L antibody, efnb2.S antibody, Efnb2 antibody

Pathways: RTK Signaling, Regulation of Muscle Cell Differentiation