Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

MAPK6 antibody

MAPK6 Reactivity: Human WB, ELISA, FACS Host: Mouse Monoclonal 4E8 unconjugated
Catalog No. ABIN966092
  • Target See all MAPK6 Antibodies
    MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))
    Reactivity
    • 56
    • 46
    • 27
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 63
    • 5
    • 3
    • 1
    Mouse
    Clonality
    • 68
    • 4
    Monoclonal
    Conjugate
    • 39
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAPK6 antibody is un-conjugated
    Application
    • 51
    • 35
    • 18
    • 14
    • 13
    • 11
    • 9
    • 7
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    Purification
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of human ERK3 expressed in E. Coli.
    Clone
    4E8
    Isotype
    IgG1
    Top Product
    Discover our top product MAPK6 Primary Antibody
  • Application Notes
    Western Bloting: 1/500 - 1/2000.
    Flow cytometry: 1/200 - 1/400.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
  • Klinger, Turgeon, Lévesque, Wood, Aagaard-Tillery, Meloche: "Loss of Erk3 function in mice leads to intrauterine growth restriction, pulmonary immaturity, and neonatal lethality." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 39, pp. 16710-5, (2009) (PubMed).

    Déléris, Rousseau, Coulombe, Rodier, Tanguay, Meloche: "Activation loop phosphorylation of the atypical MAP kinases ERK3 and ERK4 is required for binding, activation and cytoplasmic relocalization of MK5." in: Journal of cellular physiology, Vol. 217, Issue 3, pp. 778-88, (2008) (PubMed).

  • Target
    MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))
    Alternative Name
    ERK3 (MAPK6 Products)
    Synonyms
    ERK3 antibody, HsT17250 antibody, PRKM6 antibody, p97MAPK antibody, 2610021I23Rik antibody, D130053K17Rik antibody, Erk3 antibody, Mapk4 antibody, Mapk63 antibody, Prkm4 antibody, Prkm6 antibody, ATMAPK6 antibody, ATMPK6 antibody, F18O19.10 antibody, MAP KINASE 6 antibody, MAP kinase 6 antibody, MAPK6 antibody, SUSERK3 antibody, erk3 antibody, p97mapk antibody, si:ch211-235f12.1 antibody, mitogen-activated protein kinase 6 antibody, MAP kinase 6 antibody, MAPK6 antibody, Mapk6 antibody, MPK6 antibody, mapk6 antibody
    Background
    The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters.
    Tissue specificity: Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts
    Synonyms: ERK3, PRKM6, p97MAPK, HsT17250, DKFZp686F03189, MAPK6
    Molecular Weight
    105kDa
    Gene ID
    5596
    Pathways
    MAPK Signaling, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C
You are here:
Support