ETV5 antibody

Catalog No. ABIN966107

Product Details anti-ETV5 Antibody

Target: ETV5 (Ets Variant 5 (ETV5))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ETV5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human ETV5 expressed in E. Coli.

Clone: 3H3

Isotype: IgG1

Application Details

Application Notes: Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Format: Liquid

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

References for anti-ETV5 antibody (ABIN966107)

Stolz, Ertych, Bastians: "Tumor suppressor CHK2: regulator of DNA damage response and mediator of chromosomal stability." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 3, pp. 401-5, (2011) (PubMed).

Mousseaux: "Obesity and cardiovascular disease: how can cardiac magnetic resonance help?" in: Journal of the American College of Cardiology, Vol. 54, Issue 8, pp. 727-9, (2009) (PubMed).

Hotta, Nakamura, Nakamura, Matsuo, Nakata, Kamohara, Miyatake, Kotani, Komatsu, Itoh, Mineo, Wada, Masuzaki, Yoneda, Nakajima, Funahashi, Miyazaki, Tokunaga, Kawamoto, Ueno, Hamaguchi, Tanaka, Yamada et al.: "Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population. ..." in: Journal of human genetics, Vol. 54, Issue 12, pp. 727-31, (2009) (PubMed).

Chotteau-Lelièvre, Révillion, Lhotellier, Hornez, Desbiens, Cabaret, de Launoit, Peyrat: "Prognostic value of ERM gene expression in human primary breast cancers." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 10, Issue 21, pp. 7297-303, (2004) (PubMed).

Target Details for ETV5

Target: ETV5 (Ets Variant 5 (ETV5))

Alternative Name: ETV5 (ETV5 Products)

Synonyms: ERM antibody, etv5 antibody, fj87h10 antibody, id:ibd5133 antibody, wu:fj87h10 antibody, zgc:55647 antibody, 1110005E01Rik antibody, 8430401F14Rik antibody, ETS variant 5 antibody, ets variant 5 antibody, ets variant 5a antibody, ETV5 antibody, Etv5 antibody, etv5a antibody

Background: ETS variant 5,transcription factor of the ETS family,divergent member of the winged helix-turn-helix superfamily,expressed in brain,placenta and other tissues involved in development.
Tissue specificity: Ubiquitous. ERM is expressed in Sertoli cells and spermatogonial stem cells (SSCs). Studies on knockout mice have shown that it is required for SSC self-renewal but not differentiation, thus affected mice exhibit progressive germ cell depletion.
Synonyms: ERM, ETV5

Molecular Weight: 58kDa

Gene ID: 2119

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development