HAND1 antibody (AA 90-190)

Catalog No. ABIN966248

Product Details anti-HAND1 Antibody

Target: HAND1 (Heart and Neural Crest Derivatives Expressed 1 (HAND1))

Binding Specificity: AA 90-190

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HAND1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of HAND1 (aa90-190) expressed in E. Coli.

Clone: 8E7A11-8C2F4

Isotype: IgG1

Application Details

Application Notes: Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Format: Liquid

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

References for anti-HAND1 antibody (ABIN966248)

Firulli, Howard, McDaid, McIlreavey, Dionne, Centonze, Cserjesi, Virshup, Firulli: "PKA, PKC, and the protein phosphatase 2A influence HAND factor function: a mechanism for tissue-specific transcriptional regulation." in: Molecular cell, Vol. 12, Issue 5, pp. 1225-37, (2003) (PubMed).

Target Details for HAND1

Target: HAND1 (Heart and Neural Crest Derivatives Expressed 1 (HAND1))

Alternative Name: HAND1 (HAND1 Products)

Synonyms: CATG antibody, CG antibody, Hxt antibody, Thing1 antibody, bHLHa27 antibody, eHand antibody, eHAND antibody, hand-1 antibody, hand1-A antibody, HXT antibody, HAND1 antibody, hxt antibody, thing1 antibody, EHAND antibody, Hand1 antibody, Ehand1 antibody, Th1 antibody, cathepsin G antibody, heart and neural crest derivatives expressed 1 antibody, heart and neural crest derivatives expressed 1 L homeolog antibody, CTSG antibody, HAND1 antibody, Hand1 antibody, hand1.L antibody, hand1 antibody

Background: HAND1: heart and neural crest derivatives expressed 1. The protein encoded by this gene belongs to the basic helixloop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation.
Synonyms: Hxt, eHand, Thing1, bHLHa27

Gene ID: 9421

Pathways: Tube Formation