MAP2K1 antibody (Mitogen-Activated Protein Kinase Kinase 1) (pSer217)

Details for Product anti-MAP2K1 Antibody No. ABIN966559
Antigen
  • Mek1
  • CFC3
  • MAPKK1
  • MEK1
  • MKK1
  • PRKMK1
  • MEKK1
  • Prkmk1
  • mek-2
  • si:ch211-242m18.2
  • wu:fj56a12
  • wu:fj61b01
  • zgc:56557
  • ATMEK1
  • F20B18.180
  • F20B18_180
  • MAP kinase/ ERK kinase 1
  • MITOGEN ACTIVATED PROTEIN KINASE KINASE
  • MITOGEN ACTIVATED PROTEIN KINASE KINASE 1
  • NMAPKK
  • MEK
  • mitogen activated protein kinase kinase 1
  • mitogen-activated protein kinase kinase 1
  • mitogen-activated protein kinase kinase 1 L homeolog
  • MAP kinase/ ERK kinase 1
  • Map2k1
  • MAP2K1
  • map2k1.L
  • map2k1
  • MEK1
Alternatives
anti-Human MAP2K1 antibody for Western Blotting
Epitope
pSer217
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Reactivity
Human, Mouse (Murine), Rat (Rattus)
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Host
Rabbit
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Conjugate
This MAP2K1 antibody is un-conjugated
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Application
Immunohistochemistry (IHC)
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Options
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human MEK1 around the phosphorylation site of serine 217 (I-D-SP-M-A).
Specificity MEK1 (phospho-Ser217) antibody detects endogenous levels of MEK1 only when phosphorylated at serine 217 Tested
Plasmids, Primers & others Plasmids, Primers & others MAP2K1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name MEK1 (MAP2K1 Antibody Abstract)
Pathways MAPK Signaling, RTK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor
Application Notes IHC: 1:50-1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Preisinger, Körner, Wind, Lehmann, Kopajtich, Barr: "Plk1 docking to GRASP65 phosphorylated by Cdk1 suggests a mechanism for Golgi checkpoint signalling." in: The EMBO journal, Vol. 24, Issue 4, pp. 753-65, 2005 (PubMed).

Yaglom, OCallaghan-Sunol, Gabai, Sherman: "Inactivation of dual-specificity phosphatases is involved in the regulation of extracellular signal-regulated kinases by heat shock and hsp72." in: Molecular and cellular biology, Vol. 23, Issue 11, pp. 3813-24, 2003 (PubMed).

Shen, Ouyang, Qu, Alonso, Sperzel, Mustelin, Kaplan, Feng: "Grap negatively regulates T-cell receptor-elicited lymphocyte proliferation and interleukin-2 induction." in: Molecular and cellular biology, Vol. 22, Issue 10, pp. 3230-6, 2002 (PubMed).

Dahan, Busuttil, Imbert, Peyron, Rampal, Czerucka: "Enterohemorrhagic Escherichia coli infection induces interleukin-8 production via activation of mitogen-activated protein kinases and the transcription factors NF-kappaB and AP-1 in T84 cells." in: Infection and immunity, Vol. 70, Issue 5, pp. 2304-10, 2002 (PubMed).

Laine, Reunanen, Ravanti, Foschi, Santra, Iozzo, Kähäri: "Activation of extracellular signal-regulated protein kinase1,2 results in down-regulation of decorin expression in fibroblasts." in: The Biochemical journal, Vol. 349, Issue Pt 1, pp. 19-25, 2001 (PubMed).

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