MSI2 antibody

Catalog No. ABIN966597

Product Details anti-MSI2 Antibody

Target: MSI2 (Musashi Homolog 2 (MSI2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MSI2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human MSI2 expressed in E. Coli.

Clone: 2C11

Isotype: IgG1

Application Details

Application Notes: Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Format: Liquid

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

References for anti-MSI2 antibody (ABIN966597)

Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).

Target Details for MSI2

Target: MSI2 (Musashi Homolog 2 (MSI2))

Alternative Name: MSI2 (MSI2 Products)

Synonyms: MSI2H antibody, 1700105C15Rik antibody, AI451722 antibody, AI563628 antibody, AW489193 antibody, Msi2h antibody, RGD1560397 antibody, MSI2 antibody, musashi-2 antibody, musashi2 antibody, xrp1 antibody, msi2 antibody, zgc:174035 antibody, zgc:63812 antibody, cb746 antibody, fi47b09 antibody, wu:fb02d08 antibody, wu:fi32d12 antibody, wu:fi47b09 antibody, musashi RNA binding protein 2 antibody, musashi RNA-binding protein 2 antibody, musashi RNA binding protein 2 S homeolog antibody, musashi RNA-binding protein 2b antibody, musashi RNA-binding protein 2a antibody, MSI2 antibody, Msi2 antibody, msi2.S antibody, msi2 antibody, msi2b antibody, msi2a antibody

Background: Msi2 (musashi homolog 2), also known as MSI2H, is a 328 amino acid protein that localizes to the cytoplasm and contains two RRM (RNA recognition motif) domains. Expressed ubiquitously at low levels, Msi2 functions as an RNA binding protein that, by regulating the expression of target mRNAs, is thought to play a role in the proliferation and maintenance of stem cells within the central nervous system. Msi2 is subject to posttranslational phosphorylation and is upregulated in response to brain injury, suggesting a role in healing and brain tissue regeneration. Chromosomal aberrations involving the Msi2 gene are associated with the progression of chronic myeloid leukemia. Multiple isoforms of Msi2 exist due to alternative splicing events.
Tissue specificity: Ubiquitous, detected at low levels.
Synonyms: MSI2H, MGC3245, FLJ36569, MSI2

Molecular Weight: 35kDa

Gene ID: 124540