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PARL antibody (AA 112-167)

PARL Reactivity: Human WB, ELISA Host: Mouse Monoclonal 8C4B2-1H12E10 unconjugated
Catalog No. ABIN966805
  • Target See all PARL Antibodies
    PARL (Presenilin Associated, Rhomboid-Like (PARL))
    Binding Specificity
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 112-167
    Reactivity
    • 21
    • 9
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 17
    • 3
    • 2
    Mouse
    Clonality
    • 19
    • 3
    Monoclonal
    Conjugate
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PARL antibody is un-conjugated
    Application
    • 12
    • 9
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of PARL (aa112-167) expressed in E. Coli.
    Clone
    8C4B2-1H12E10
    Isotype
    IgG2b
    Top Product
    Discover our top product PARL Primary Antibody
  • Application Notes
    Western Bloting: 1/500 - 1/2000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
  • Pellegrini, Passer, Canelles, Lefterov, Ganjei, Fowlkes, Koonin, DAdamio: "PAMP and PARL, two novel putative metalloproteases interacting with the COOH-terminus of Presenilin-1 and -2." in: Journal of Alzheimer's disease : JAD, Vol. 3, Issue 2, pp. 181-190, (2002) (PubMed).

  • Target
    PARL (Presenilin Associated, Rhomboid-Like (PARL))
    Alternative Name
    PARL (PARL Products)
    Synonyms
    PSARL antibody, PSARL1 antibody, PSENIP2 antibody, RHBDS1 antibody, D16Ertd607e antibody, PRO2207 antibody, Psarl antibody, parl antibody, zgc:112986 antibody, presenilin associated rhomboid like antibody, presenilin associated, rhomboid-like antibody, presenilin associated, rhomboid-like a antibody, PARL antibody, Parl antibody, parla antibody
    Background
    PARL: presenilin associated, rhomboid-like. This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.
    Synonyms: PSARL, PSARL1, RHBDS1
    Gene ID
    55486
    Pathways
    Autophagy
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