SARS-Coronavirus Membrane Protein (SARS-CoV M) antibody

Catalog No. ABIN966994

Product Details

Target: SARS-Coronavirus Membrane Protein (SARS-CoV M)

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB)

Purification: Subclonal supernatant.

Immunogen: Purified recombinant fragment of SARS-m protein expressed in E. Coli.

Clone: 2H2C4

Isotype: IgG1

Application Details

Application Notes: Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: 4 °C

References

de Haan, Smeets, Vernooij, Vennema, Rottier: "Mapping of the coronavirus membrane protein domains involved in interaction with the spike protein." in: Journal of virology, Vol. 73, Issue 9, pp. 7441-52, (1999) (PubMed).

Blomhoff, Smedsrød, Eskild, Granum, Berg: "Preparation of isolated liver endothelial cells and Kupffer cells in high yield by means of an enterotoxin." in: Experimental cell research, Vol. 150, Issue 1, pp. 194-204, (1984) (PubMed).

Target Details

Target: SARS-Coronavirus Membrane Protein (SARS-CoV M)

Alternative Name: SARS-M (SARS-CoV M Products)

Synonyms: M protein antibody, matrix protein antibody, M antibody

Target Type: Viral Protein

Background: SARS (severe acute respiratory syndrome) is caused by a human coronavirus. Human coronaviruses are the major cause of upper respiratory tract illness, such as the common cold, in humans. Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The complete sequence of the SARS virus release the coronavirus contains 25 open reading frames. SARS-m is a membrane (M) protein which plays a the key player in virion assembly. One of its functions is to mediate the incorporation of the spikes into the viral envelope.