SLC18A2 antibody (C-Term)

Catalog No. ABIN967117

Product Details anti-SLC18A2 Antibody

Target: SLC18A2 (Solute Carrier Family 18 (Vesicular Monoamine Transporter), Member 2 (SLC18A2))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC18A2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human SVMT(Synaptic vesicular amine transporter)

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C

References for anti-SLC18A2 antibody (ABIN967117)

Thiriot, Sievert, Ruoho: "Identification of human vesicle monoamine transporter (VMAT2) lumenal cysteines that form an intramolecular disulfide bond." in: Biochemistry, Vol. 41, Issue 20, pp. 6346-53, (2002) (PubMed).

Peter, Finn, Klisak, Liu, Kojis, Heinzmann, Roghani, Sparkes, Edwards: "Chromosomal localization of the human vesicular amine transporter genes." in: Genomics, Vol. 18, Issue 3, pp. 720-3, (1994) (PubMed).

Surratt, Persico, Yang, Edgar, Bird, Hawkins, Griffin, Li, Jabs, Uhl: "A human synaptic vesicle monoamine transporter cDNA predicts posttranslational modifications, reveals chromosome 10 gene localization and identifies TaqI RFLPs." in: FEBS letters, Vol. 318, Issue 3, pp. 325-30, (1993) (PubMed).

Erickson, Eiden: "Functional identification and molecular cloning of a human brain vesicle monoamine transporter." in: Journal of neurochemistry, Vol. 61, Issue 6, pp. 2314-7, (1993) (PubMed).

Target Details for SLC18A2

Target: SLC18A2 (Solute Carrier Family 18 (Vesicular Monoamine Transporter), Member 2 (SLC18A2))

Alternative Name: SVMT (SLC18A2 Products)

Synonyms: 1110037L13Rik antibody, 9330105E13 antibody, VAT2 antibody, Vmat2 antibody, MNAT antibody, VMAT-2 antibody, VMAT2 antibody, solute carrier family 18 (vesicular monoamine), member 2 antibody, solute carrier family 18 member A2 antibody, Slc18a2 antibody

Background: SVMT(Synaptic vesicular amine transporter) is involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. SVMT is requisite for vesicular amine storage prior to secretion via exocytosis. SVMT belongs to the major facilitator superfamily and vesicular transporter family.