TYRO3 antibody (TYRO3 Protein Tyrosine Kinase)

Details for Product anti-TYRO3 Antibody No. ABIN967222, Supplier: Log in to see
Antigen
  • TYRO3
  • brt
  • byk
  • dtk
  • rse
  • sky
  • tif
  • Xksy
  • MGC145734
  • DKFZp469I0432
  • LOC100231598
  • BYK
  • Dtk
  • RSE
  • Sky
  • Tif
  • Brt
  • REK
  • ksy
  • xksy
  • AI323366
  • Etk-2
  • Rse
  • TYRO3 protein tyrosine kinase
  • TYRO3 protein tyrosine kinase L homeolog
  • TYRO3 protein tyrosine kinase 3
  • TYRO3
  • tyro3
  • Tyro3
  • tyro3.L
Alternatives
anti-Human TYRO3 antibody for ELISA
Reactivity
Human
167
62
25
6
1
1
Host
Mouse
102
67
18
Clonality (Clone)
Monoclonal ()
Conjugate
This TYRO3 antibody is un-conjugated
5
4
4
4
4
4
4
4
3
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
113
62
49
46
40
26
24
20
13
10
5
4
2
2
1
Options
Supplier
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Supplier Product No.
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Immunogen Purified recombinant fragment of Tyro3 expressed in E. Coli.
Clone 7A10C11-7A10G4
Purification Ascitic fluid
Alternative Name Tyro3 (TYRO3 Antibody Abstract)
Background Tyro3 (also known as Sky and Rse), with 890-amino acid protein (about 98kDa), belongs to the Axl/Tyro3 family of receptor tyrosine kinases, which also includes Axl and Mer.Gas6 (growth arrest-specific gene-6) is a ligand for all members of the Axl family and they play essential roles in spermatogenesis, immunoregulation, and phagocytosis.Tyro3 was expressed at high levels during postnatal development and in the adult in the cortex.Tyro3 and Gas6 have neurotrophic roles in the nervous system.In addition, the signalling interactions of Axl and Tyro3 may play roles in tumourigenesis, inflammation as well as other cell proliferative diseases.
Synonyms: BYK, Brt, Dtk, RSE, Sky, Tif, FLJ16467
Gene ID 7301
Pathways RTK Signaling
Application Notes Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Background publications Hafizi, Gustafsson, Stenhoff, Dahlbäck: "The Ran binding protein RanBPM interacts with Axl and Sky receptor tyrosine kinases." in: The international journal of biochemistry & cell biology, Vol. 37, Issue 11, pp. 2344-56, 2005 (PubMed).

Product cited in: Heiring, Dahlbäck, Muller: "Ligand recognition and homophilic interactions in Tyro3: structural insights into the Axl/Tyro3 receptor tyrosine kinase family." in: The Journal of biological chemistry, Vol. 279, Issue 8, pp. 6952-8, 2004 (PubMed).

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