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TYRO3 antibody (AA 138-321)

TYRO3 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 6D6F10 unconjugated
Catalog No. ABIN967223
  • Target See all TYRO3 Antibodies
    TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))
    Binding Specificity
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 138-321
    Reactivity
    • 44
    • 18
    • 12
    • 4
    Human
    Host
    • 31
    • 17
    • 1
    Mouse
    Clonality
    • 31
    • 18
    Monoclonal
    Conjugate
    • 35
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TYRO3 antibody is un-conjugated
    Application
    • 30
    • 18
    • 10
    • 8
    • 8
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of Tyro3 (aa138-321) expressed in E. Coli.
    Clone
    6D6F10
    Isotype
    IgG1
    Top Product
    Discover our top product TYRO3 Primary Antibody
  • Application Notes
    Immunofluorescence: 1/200 - 1/1000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
  • Heiring, Dahlbäck, Muller: "Ligand recognition and homophilic interactions in Tyro3: structural insights into the Axl/Tyro3 receptor tyrosine kinase family." in: The Journal of biological chemistry, Vol. 279, Issue 8, pp. 6952-8, (2004) (PubMed).

  • Target
    TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))
    Alternative Name
    Tyro3 (TYRO3 Products)
    Synonyms
    TYRO3 antibody, brt antibody, byk antibody, dtk antibody, rse antibody, sky antibody, tif antibody, Xksy antibody, MGC145734 antibody, DKFZp469I0432 antibody, LOC100231598 antibody, BYK antibody, Dtk antibody, RSE antibody, Sky antibody, Tif antibody, Brt antibody, REK antibody, ksy antibody, xksy antibody, AI323366 antibody, Etk-2 antibody, Rse antibody, TYRO3 protein tyrosine kinase antibody, TYRO3 protein tyrosine kinase L homeolog antibody, TYRO3 protein tyrosine kinase 3 antibody, TYRO3 antibody, tyro3 antibody, Tyro3 antibody, tyro3.L antibody
    Background
    Tyro3 (also known as Sky and Rse), with 890-amino acid protein (about 98kDa), belongs to the Axl/Tyro3 family of receptor tyrosine kinases, which also includes Axl and Mer.Gas6 (growth arrest-specific gene-6) is a ligand for all members of the Axl family and they play essential roles in spermatogenesis, immunoregulation, and phagocytosis.Tyro3 was expressed at high levels during postnatal development and in the adult in the cortex.Tyro3 and Gas6 have neurotrophic roles in the nervous system.In addition, the signalling interactions of Axl and Tyro3 may play roles in tumourigenesis, inflammation as well as other cell proliferative diseases.
    Synonyms: BYK, Brt, Dtk, RSE, Sky, Tif, FLJ16467
    Gene ID
    7301
    Pathways
    RTK Signaling
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