AKT3 antibody
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- Target See all AKT3 Antibodies
- AKT3 (V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) (AKT3))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This AKT3 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purification
- purified
- Immunogen
- Purified recombinant fragment of Akt3 expressed in E. coli.
- Clone
- 3B12F3F10
- Top Product
- Discover our top product AKT3 Primary Antibody
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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Role for Akt3/protein kinase Bgamma in attainment of normal brain size." in: Molecular and cellular biology, Vol. 25, Issue 5, pp. 1869-78, (2005) (PubMed).
: "Deregulated Akt3 activity promotes development of malignant melanoma." in: Cancer research, Vol. 64, Issue 19, pp. 7002-10, (2004) (PubMed).
: "
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Role for Akt3/protein kinase Bgamma in attainment of normal brain size." in: Molecular and cellular biology, Vol. 25, Issue 5, pp. 1869-78, (2005) (PubMed).
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- Target
- AKT3 (V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) (AKT3))
- Alternative Name
- Akt3 (AKT3 Products)
- Synonyms
- MPPH antibody, PKB-GAMMA antibody, PKBG antibody, PRKBG antibody, RAC-PK-gamma antibody, RAC-gamma antibody, STK-2 antibody, AI851531 antibody, D930002M15Rik antibody, Nmf350 antibody, Pkbg antibody, AKT serine/threonine kinase 3 antibody, thymoma viral proto-oncogene 3 antibody, v-akt murine thymoma viral oncogene homolog 3b antibody, AKT3 antibody, Akt3 antibody, akt3b antibody
- Background
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Description: Akt3 (also designated protein kinase B gamma or v-akt murine thymoma viral oncogene homolog 3),with 479-amino acid protein (about 53 kDa), belongs to the AKT serine/threonine protein kinase family, which also includes Akt1 and Akt2. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake.Akt3 is not required for the maintenance of normal carbohydrate metabolism but is essential for the attainment of normal organ size. Identifying Akt3 as a selective target in melanoma cells also provides new therapeutic opportunities for patients in the advanced stages of this disease.
Aliases: Akt3
- Gene ID
- 10000
- HGNC
- 10000
- Pathways
- PI3K-Akt Signaling, RTK Signaling, TLR Signaling, Hepatitis C, VEGF Signaling
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