cAMP antibody (Cyclic Adenosine Monophosphate)

Details for Product anti-cAMP Antibody No. ABIN969001
Antigen
  • CRAMP
  • CAP-18
  • CAP18
  • FALL-39
  • FALL39
  • LL37
  • CAP11
  • Cnlp
  • Cramp
  • MCLP
  • CATHL7
  • cathelicidin antimicrobial peptide
  • Camp
  • CAMP
Reactivity
Chemical
34
25
7
6
4
4
Host
Mouse
66
15
12
1
Clonality (Clone)
Monoclonal ()
Conjugate
This cAMP antibody is un-conjugated
5
3
2
1
1
1
1
1
1
1
1
1
Application
ELISA
44
43
21
13
6
4
3
3
3
2
2
1
1
1
Options
Immunogen cAMP, conjugated to KLH.
Clone 9H4C4
Isotype IgG1
Purification Ascites
Plasmids, Primers & others Plasmids, Primers & others cAMP products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name cAMP (cAMP Antibody Abstract)
Target Type Chemical
Background Cyclic adenosine monophosphate (cAMP) plays a key role as an intracellular second messenger for transduction events that follow a number of extracellular signals. The G-Protein Coupled Receptors (GPCR) is the largest family of cell surface receptors. They can be activated by different ligands, such as neurotransmitters, hormones, ions, small molecules, peptides, and other physiological signaling molecules. Typically, the binding of the ligands to its receptor resulting in the activation of G-proteins, in return, activates the effector adenylyl cyclase evoking the production of cAMP. The activation of a protein kinase by cAMP results in the phosphorylation of substrate proteins. Currently successful drugs in marketing have been developed to target these receptors. Among the GPCRs, ~367 receptors are potential drug development targets, but only about 20 have been used to generate therapeutically and commercially successful drugs so far. Because the involvement of cAMP can amplify the response of the ligand binding, the second messenger cAMP has been largely employed to monitor the activation of the GPCR to facilitate the therapeutic drug discovery
Pathways Cellular Response to Molecule of Bacterial Origin
Application Notes ELISA: 1:10000
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
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