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GPI antibody

GPI Reactivity: Human WB, ELISA, IHC, ICC Host: Mouse Monoclonal 1B7D7 unconjugated
Catalog No. ABIN969176
  • Target See all GPI Antibodies
    GPI (Glucose-6-Phosphate Isomerase (GPI))
    Reactivity
    • 72
    • 53
    • 12
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Human
    Host
    • 102
    • 13
    • 1
    Mouse
    Clonality
    • 97
    • 19
    Monoclonal
    Conjugate
    • 59
    • 9
    • 9
    • 8
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    This GPI antibody is un-conjugated
    Application
    • 92
    • 48
    • 21
    • 16
    • 15
    • 14
    • 14
    • 9
    • 8
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human GPI expressed in E. coli.
    Clone
    1B7D7
    Isotype
    IgG1
    Top Product
    Discover our top product GPI Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Schaller, Stohl, Benoit, Tan, Johansen, Ditzel: "Patients with inflammatory arthritic diseases harbor elevated serum and synovial fluid levels of free and immune-complexed glucose-6-phosphate isomerase (G6PI)." in: Biochemical and biophysical research communications, Vol. 349, Issue 2, pp. 838-45, (2006) (PubMed).

    Haga, Komazaki, Funasaka, Hashimoto, Yokoyama, Watanabe, Raz, Nagase: "AMF/G6PI induces differentiation of leukemic cells via an unknown receptor that differs from gp78." in: Leukemia & lymphoma, Vol. 47, Issue 10, pp. 2234-43, (2006) (PubMed).

    Muraki, Matsumoto, Chino, Hayashi, Suzuki, Goto, Ito, Murata, Tsutsumi, Sumida: "Glucose-6-phosphate isomerase variants play a key role in the generation of anti-GPI antibodies: possible mechanism of autoantibody production." in: Biochemical and biophysical research communications, Vol. 323, Issue 2, pp. 518-22, (2004) (PubMed).

  • Target
    GPI (Glucose-6-Phosphate Isomerase (GPI))
    Alternative Name
    Glucose-6-phosphate isomerase (GPI Products)
    Synonyms
    PGI antibody, Amf antibody, Gpi1 antibody, GPI antibody, DDBDRAFT_0185620 antibody, DDBDRAFT_0231026 antibody, DDB_0185620 antibody, DDB_0231026 antibody, CG8251 antibody, Dmel\\CG8251 antibody, Gpi antibody, pgi antibody, Gpi-1 antibody, Gpi-1r antibody, Gpi-1s antibody, Gpi-1t antibody, Gpi1-r antibody, Gpi1-s antibody, Gpi1-t antibody, Gpi1s antibody, MF antibody, NK antibody, NK/GPI antibody, Org antibody, AMF antibody, GNPI antibody, NLK antibody, PHI antibody, SA-36 antibody, SA36 antibody, gpi antibody, pgi-2 antibody, glucose-6-phosphate isomerase antibody, gpi antibody, glucose-6-phosphate isomerase 1 antibody, gpi Glucose-6-phosphate isomerase antibody, Phosphoglucose isomerase antibody, glucose phosphate isomerase 1 antibody, glucose-6-phosphate isomerase b antibody, GPI antibody, Gpi antibody, gpi antibody, pgi antibody, GPI1 antibody, Pgi antibody, Gpi1 antibody, gpib antibody
    Target Type
    Viral Protein
    Background

    Description: Glucose-6-phosphate isomerase, or phosphoglucose isomerase, also known as GPI. It belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways and it is an enzyme that catalyzes the conversion of glucose-6-phosphate into fructose 6-phosphate in the second step of glycolysis. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in GPI are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.

    Aliases: AMF, NLK, PGI, PHI, GNPI, SA-36, GPI

    Molecular Weight
    63 kDa
    Gene ID
    2821
    HGNC
    2821
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