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ISL1 antibody

ISL1 Reactivity: Human WB, ELISA, ICC Host: Mouse Monoclonal 1B1 unconjugated
Catalog No. ABIN969220
  • Target See all ISL1 Antibodies
    ISL1 (ISL LIM Homeobox 1 (ISL1))
    Reactivity
    • 70
    • 43
    • 27
    • 8
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 68
    • 10
    Mouse
    Clonality
    • 56
    • 22
    Monoclonal
    Conjugate
    • 41
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ISL1 antibody is un-conjugated
    Application
    • 59
    • 31
    • 14
    • 13
    • 8
    • 7
    • 5
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human ISL1 expressed in E. coli.
    Clone
    1B1
    Isotype
    IgG1
    Top Product
    Discover our top product ISL1 Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Elshatory, Gan: "The LIM-homeobox gene Islet-1 is required for the development of restricted forebrain cholinergic neurons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 28, Issue 13, pp. 3291-7, (2008) (PubMed).

  • Target
    ISL1 (ISL LIM Homeobox 1 (ISL1))
    Alternative Name
    ISL1 (ISL1 Products)
    Synonyms
    Xisl-1 antibody, Xislet-1 antibody, islet1 antibody, ISLET-1 antibody, ISLET1 antibody, Isl-1 antibody, islet-1 antibody, isl-1=homeobox antibody, Islet-1 antibody, ISL LIM homeobox 1 S homeolog antibody, ISL LIM homeobox 1 antibody, ISL1 transcription factor, LIM/homeodomain antibody, isl1.S antibody, ISL1 antibody, Isl1 antibody, isl1 antibody
    Background

    Description: ISL1 (ISL1 transcription factor, LIM/homeodomain) is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. It is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Islet-1 expression defines cardiac progenitor cell populations and is required for normal cardiac development and asymmetry. Mutations in this gene have been associated with maturity-onset diabetes of the young.

    Aliases: Isl-1, ISLET1

    Molecular Weight
    39 kDa
    Gene ID
    3670
    HGNC
    3670
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
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