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Submit your validation data for this product and get a full refund. I want to validate this productRelevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
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13.98401 | ABIN652856 | FACS IF IHC (p) WB | Rabbit | Ig Fraction | AA 70-98, N-Term | Log in to see | Polyclonal | 1 | ||
13.98401 | ABIN4278820 | ELISA FACS ICC IF IHC WB | Mouse | IgG2b | Log in to see | 4E7 | 0 | |||
13.98401 | ABIN1845959 | ELISA FACS IF/ICC IHC WB | Mouse | IgG2b | Log in to see | 0 | ||||
1 | ABIN5533680 | FACS IF IHC (p) WB | Rabbit | Ig Fraction | AA 70-98, N-Term | Log in to see | Polyclonal | 0 | ||
1 | ABIN4902860 | FACS IF IHC WB | Rabbit | IgG | Log in to see | Polyclonal | 0 | |||
1 | ABIN5682435 | ELISA FACS ICC IF IHC WB | Mouse | IgG2b | Log in to see | 4E7 | 0 | |||
1 | ABIN4880194 | ELISA FACS ICC IHC WB | Mouse | IgG2b | Log in to see | 4E7 | 0 | |||
1 | ABIN2197809 | FACS IHC ELISA WB | Mouse | IgG2b | Log in to see | 13B19 | 0 | |||
1 | ABIN5074914 | ELISA FACS ICC IF WB | Mouse | IgG2a kappa | AA 98-609 | Log in to see | 22E9 | 0 | ||
1 | ABIN5074915 | ELISA FACS ICC IF WB | Mouse | IgG2a kappa | AA 98-609 | Log in to see | 22E9 | 0 | ||
1 | ABIN5572241 | ELISA FACS IF IHC (p) WB | Mouse | IgG2b | Log in to see | 4E7 | 0 | |||
1 | ABIN2800675 | FACS IF IHC WB | Rabbit | Ig Fraction | N-Term | Log in to see | Polyclonal | 0 |
General |
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Antigen | Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) Antibodies |
Reactivity | Human, Mouse (Murine), Monkey, Rat (Rattus) Alternatives |
Host | Mouse Alternatives |
Clonality (Clone) | |
Conjugate | This AIFM1 antibody is un-conjugated Alternatives |
Application |
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
Alternatives
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1 reference available |
Supplier | Log in to see |
Product Details anti-AIFM1 AntibodyTarget Details AIFM1 Application Details Handling References for anti-AIFM1 antibody (ABIN968950) Images |
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Purification | Ascites |
Immunogen | Purified recombinant fragment of human AIF expressed in E. Coli. |
Clone | 4-00E-07 |
Isotype | IgG2b |
Target Details AIFM1Product Details anti-AIFM1 Antibody Application Details Handling References for anti-AIFM1 antibody (ABIN968950) Images back to top |
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Antigen | |
Alternative Name | AIF (AIFM1 Antibody Abstract) |
Background | This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10 |
Molecular Weight | 67 kDa |
Gene ID | 9131 |
HGNC | 9131 |
Pathways | Apoptosis, Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis, Smooth Muscle Cell Migration |
Application DetailsProduct Details anti-AIFM1 Antibody Target Details AIFM1 Handling References for anti-AIFM1 antibody (ABIN968950) Images back to top |
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Application Notes | ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400 |
Restrictions | For Research Use only |
HandlingProduct Details anti-AIFM1 Antibody Target Details AIFM1 Application Details References for anti-AIFM1 antibody (ABIN968950) Images back to top |
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Format | Liquid |
Buffer | Ascitic fluid containing 0.03 % sodium azide. |
Preservative | Sodium azide |
Precaution of Use | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Storage | 4 °C,-20 °C |
Storage Comment | 4°C, -20°C for long term storage |
References for anti-AIFM1 antibody (ABIN968950)Product Details anti-AIFM1 Antibody Target Details AIFM1 Application Details Handling Images back to top |
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Product cited in: |
Son, Jang, Heo, Chung, Choi, Lee: "Apoptosis-inducing factor plays a critical role in caspase-independent, pyknotic cell death in hydrogen peroxide-exposed cells." in: Apoptosis : an international journal on programmed cell death, Vol. 14, Issue 6, pp. 796-808, 2009 |
ImagesProduct Details anti-AIFM1 Antibody Target Details AIFM1 Application Details Handling References for anti-AIFM1 antibody (ABIN968950) back to top |
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Supplier Images |
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