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Submit your validation data for this product and get a full refund. I want to validate this productRelevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
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1 | ABIN371611 | FACS IHC (fro) IP WB | Mouse | IgG3 | Log in to see | 7B2-5 | 15 | |||
1 | ABIN223050 | IP WB | Rabbit | IgG | Log in to see | Polyclonal | 3 | |||
1 | ABIN967828 | IF IP IHC WB | Mouse | IgG2b | AA 18-233 | Log in to see | 4-Bcl | 5 | ||
1 | ABIN967827 | IF IP IHC WB | Mouse | IgG2b | AA 18-233 | Log in to see | 4-Bcl | 5 | ||
1 | ABIN968153 | IF IP IHC WB | Mouse | IgG1 | AA 18-233 | Log in to see | 44-Bcl | 5 | ||
1 | ABIN968152 | IF IP IHC WB | Mouse | IgG1 | AA 18-233 | Log in to see | 44-Bcl | 5 | ||
1 | ABIN4283629 | IHC IHC (fro) IHC (p) IP WB | Rabbit | Log in to see | Polyclonal | 1 | ||||
1 | ABIN4283632 | IHC IHC (fro) IHC (p) IP WB | Rabbit | Log in to see | Polyclonal | 1 | ||||
1 | ABIN4283652 | ELISA FACS ICC IF IHC (fro) IHC (p) IP WB | Mouse | IgG2a | AA 3-14 | Log in to see | BX006 | 0 | ||
1 | ABIN957162 | ICC IHC (fro) IHC (p) IP WB | Rabbit | AA 46-66 | Log in to see | Polyclonal | 0 | |||
1 | ABIN1001877 | IP WB | Rabbit | IgG | Log in to see | Polyclonal | 0 | |||
1 | ABIN205526 | FACS IP IHC WB | Mouse | IgG2a | AA 3-14 | Log in to see | 2H12 | 0 | ||
1 | ABIN957161 | IHC (fro) IHC (p) IP WB | Rabbit | Log in to see | Polyclonal | 0 | ||||
1 | ABIN155068 | IP WB | Rabbit | Log in to see | Polyclonal | 0 | ||||
1 | ABIN4283653 | FACS ICC IF IHC (fro) IHC (p) IP WB | Mouse | IgG2a | AA 3-14 | Log in to see | SPM165 | 0 | ||
1 | ABIN4283655 | FACS ICC IF IHC (fro) IHC (p) IP WB | Mouse | IgG2a | AA 3-14 | Log in to see | SPM165 | 0 | ||
1 | ABIN4283657 | FACS ICC IF IHC (fro) IHC (p) IP WB | Mouse | IgG2a | AA 3-14 | Log in to see | 2H12 | 0 | ||
1 | ABIN4283658 | FACS ICC IF IHC (fro) IHC (p) IP WB | Mouse | IgG2a | AA 3-14 | Log in to see | 2H12 | 0 | ||
1 | ABIN4283680 | FACS ICC IF IHC (fro) IHC (p) IP WB | Mouse | IgG | AA 3-14 | Log in to see | BX006-2H12 | 0 | ||
1 | ABIN4283679 | FACS ICC IF IHC (fro) IHC (p) IP WB | Mouse | IgG | AA 3-14 | Log in to see | BX006-2H12 | 0 |
General |
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Antigen | BCL2-Like 1 (BCL2L1) Antibodies |
Epitope | Center Alternatives |
Reactivity | Human, Mouse (Murine), Rat (Rattus) Alternatives |
Host | Rabbit Alternatives |
Clonality | |
Conjugate | This BCL2L1 antibody is un-conjugated Alternatives |
Application |
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Alternatives
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Supplier | Log in to see |
Product Details anti-BCL2L1 AntibodyTarget Details BCL2L1 Application Details Handling Images |
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Cross-Reactivity | Dog (Canine) |
Cross-Reactivity (Details) | Dog (100 %) |
Characteristics |
Rabbit Polyclonal antibody to Bcl-X (BCL2-like 1) Bcl-X antibody |
Purification | Purified by antigen-affinity chromatography. |
Immunogen | Recombinant protein encompassing a sequence within the center region of human Bcl-X. The exact sequence is proprietary. |
Isotype | IgG |
Target Details BCL2L1Product Details anti-BCL2L1 Antibody Application Details Handling Images back to top |
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Antigen | |
Alternative Name | Bcl-X (BCL2L1 Antibody Abstract) |
Background |
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. Cellular Localization: Mitochondrion membrane, Single-pass membrane protein , Nucleus membrane, Single-pass membrane protein, Cytoplasmic side , Mitochondrion membrane , Nucleus membrane |
Molecular Weight | 26 kDa |
Gene ID | 598 |
Pathways | Apoptosis, Negative Regulation of intrinsic apoptotic Signaling |
Application DetailsProduct Details anti-BCL2L1 Antibody Target Details BCL2L1 Handling Images back to top |
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Application Notes | Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Immunoprecipitation 1:100-1:500* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Immunoprecipitation1:100-1:500* Western blot1:500-1:3000* |
Comment |
Positive Control: HCT116 , NIH-3T3 , PC-12 , *OKT3 |
Restrictions | For Research Use only |
HandlingProduct Details anti-BCL2L1 Antibody Target Details BCL2L1 Application Details Images back to top |
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Format | Liquid |
Concentration | 0.95 mg/mL |
Buffer | 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative. |
Preservative | Thimerosal (Merthiolate) |
Precaution of Use | This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Storage | -20 °C |
Storage Comment | Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles. |
ImagesProduct Details anti-BCL2L1 Antibody Target Details BCL2L1 Application Details Handling back to top |
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Supplier Images |
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