anti-Human BIRC5 antibody for Western Blotting

Recommended BIRC5 Antibody (supplied by: Log in to see )

Antigen
Baculoviral IAP Repeat-Containing 5 (BIRC5) Antibodies
  • API4
  • EPR-1
  • AAC-11
  • Api4
  • TIAP
  • survivin40
  • AP14
  • baculoviral IAP repeat containing 5
  • baculoviral IAP repeat-containing 5-like
  • baculoviral IAP repeat-containing 5
  • BIRC5
  • LOC696283
  • Birc5
Epitope
AA 121-142, C-Term
16
10
5
5
4
3
1
1
1
1
1
1
1
1
1
Reactivity
Human
77
27
7
1
1
1
Host
Rabbit
59
29
4
Clonality
Polyclonal
Conjugate
This BIRC5 antibody is un-conjugated
5
3
2
1
1
1
1
1
Application
Western Blotting (WB)
68
26
24
16
14
12
6
3
2
2
2
2
1
1
1
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Catalog No. ABIN3043195
$ 240.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.2008362 ABIN3042792 IHC (p) ELISA WB Rabbit IgG AA 1-142 Log in to see Polyclonal 4
3.2008362 ABIN396525 WB Mouse IgG2a kappa AA 1-101 Log in to see 5B10 5
3.2008362 ABIN4900855 CyTOF FACS IHC SimWes WB Goat IgG Log in to see Polyclonal 2
3.2008362 ABIN1875407 IF IHC WB Rabbit IgG Log in to see Polyclonal 0
3.2008362 ABIN559893 IF IP RNAi ELISA WB Mouse IgG2a kappa AA 1-100, partial Log in to see 5B10 2
3.2008362 ABIN969504 ICC FACS IHC ELISA WB Mouse IgG1 Log in to see 1H5 0
3.2008362 ABIN947570 IF IP WB Rabbit AA 1-142, full length Log in to see Polyclonal 0
3.2008362 ABIN513406 IF PLA WB Rabbit AA 1-142, full length Log in to see Polyclonal 0
3.2008362 ABIN2465183 ELISA WB Goat C-Term Log in to see Polyclonal 0
3.2008362 ABIN5611620 EIA IF IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
3.2008362 ABIN2723214 FACS IF WB Mouse IgG1 Log in to see 2D9 0
3.2008362 ABIN1845166 ELISA FACS IF/ICC IHC WB Mouse IgG1 Log in to see 0
3.2008362 ABIN1107626 WB Mouse IgG1 Log in to see 2H5H2 3
3.2008362 ABIN513405 IF WB Mouse AA 1-142, full length Log in to see Polyclonal 0
3.2008362 ABIN2428785 IHC ELISA WB Rabbit IgG Log in to see Polyclonal 0
3.2008362 ABIN306761 WB Rabbit IgG N-Term Log in to see Polyclonal 2
3.2008362 ABIN306760 WB Rabbit IgG C-Term Log in to see Polyclonal 2
1 ABIN5555279 EIA IF WB Rabbit IgG N-Term Log in to see Polyclonal 0
1 ABIN5555280 EIA IF WB Rabbit IgG C-Term Log in to see Polyclonal 0
1 ABIN5552989 WB Goat C-Term Log in to see Polyclonal 0

General

Antigen Baculoviral IAP Repeat-Containing 5 (BIRC5) Antibodies
Epitope AA 121-142, C-Term
(16), (10), (5), (5), (4), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(77), (27), (7), (1), (1), (1)
Host Rabbit
(59), (29), (4)
Clonality
Polyclonal
Conjugate This BIRC5 antibody is un-conjugated
(5), (3), (2), (1), (1), (1), (1), (1)
Application Western Blotting (WB)
(68), (26), (24), (16), (14), (12), (6), (3), (2), (2), (2), (2), (1), (1), (1)
Pubmed 6 references available
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Product Details anti-BIRC5 Antibody

Target Details BIRC5 Application Details Handling References for anti-BIRC5 antibody (ABIN3043195) Images
Purpose Rabbit IgG polyclonal antibody for Baculoviral IAP repeat-containing protein 5(BIRC5) detection. Tested with WB in Human.
Sequence KKEFEETAKK VRRAIEQLAA MD
Cross-Reactivity (Details) No cross reactivity with other proteins.
Characteristics Rabbit IgG polyclonal antibody for Baculoviral IAP repeat-containing protein 5(BIRC5) detection. Tested with WB in Human.
Gene Name: baculoviral IAP repeat containing 5
Protein Name: Baculoviral IAP repeat-containing protein 5
Purification Immunogen affinity purified.
Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of human survivin(121-142aa KKEFEETAKKVRRAIEQLAAMD).
Isotype IgG

Target Details BIRC5

Product Details anti-BIRC5 Antibody Application Details Handling References for anti-BIRC5 antibody (ABIN3043195) Images back to top
Antigen
Alternative Name BIRC5 (BIRC5 Antibody Abstract)
Background Survivin, also called baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5, is a protein that, in humans, is encoded by the BIRC5 gene. Survivin is a member of the inhibitor of apoptosis(IAP) family. The survivin gene contains 4 exons. The survivin gene is mapped to chromosome 17q25 by pulsed field gel electrophoresis and single- and 2-color FISH. The survivin protein functions to inhibit caspase activation, thereby leading to negative regulation of apoptosis or programmed cell death. The survivin protein is expressed highly in most human tumours and fetal tissue, but is completely absent in terminally differentiated cells.

Synonyms: API4 antibody|Apoptosis Inhibitor 4 antibody|Apoptosis inhibitor survivin antibody|Apoptosis inhibitor4 antibody|Baculoviral IAP repeat containing 5 antibody|Baculoviral IAP repeat containing protein 5 antibody|Baculoviral IAP repeat-containing protein 5 antibody|BIRC 5 antibody|BIRC5 antibody|EPR 1 antibody|IAP4 antibody|Survivin variant 3 alpha antibody|SVV antibody|TIAP antibody
UniProt O15392
Pathways Apoptosis, Cell Division Cycle

Application Details

Product Details anti-BIRC5 Antibody Target Details BIRC5 Handling References for anti-BIRC5 antibody (ABIN3043195) Images back to top
Application Notes WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.
Comment

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions For Research Use only

Handling

Product Details anti-BIRC5 Antibody Target Details BIRC5 Application Details References for anti-BIRC5 antibody (ABIN3043195) Images back to top
Format Lyophilized
Reconstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Concentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
Preservative Thimerosal (Merthiolate), Sodium azide
Precaution of Use This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Expiry Date 12 months

References for anti-BIRC5 antibody (ABIN3043195)

Product Details anti-BIRC5 Antibody Target Details BIRC5 Application Details Handling Images back to top
Product cited in:

Li, Zhao, Lu, Li, Yang, Wu, Liu: "Notch-1 signaling promotes the malignant features of human breast cancer through NF-?B activation." in: PLoS ONE, Vol. 9, Issue 4, pp. e95912, 2014

Zhang, Lu, Hou, Hu, Wang: "The effects of STAT3 and Survivin silencing on the growth of human bladder carcinoma cells." in: Tumour biology, Vol. 35, Issue 6, pp. 5401-7, 2014

Hao, Huang, Liao, Zhu, Liu, Hao, Liu, Zhang, Feng, Ning, Li, Li: "The inhibition of resveratrol to human skin squamous cell carcinoma A431 xenografts in nude mice." in: Fitoterapia, Vol. 86, pp. 84-91, 2013

Li, Zhang, Fang, Yan, Zhao, Feng, Ma, Ye: "Aspirin overcomes Navitoclax-resistance in hepatocellular carcinoma cells through suppression of Mcl-1." in: Biochemical and biophysical research communications, Vol. 434, Issue 4, pp. 809-14, 2013

Cai, Liu, Zhao, Wan, Hu, Zhou, Chen: "Expressions of survivin and vascular endothelial growth factor in a Murine model of proliferative retinopathy." in: International journal of ophthalmology, Vol. 5, Issue 3, pp. 293-6, 2012

Shan, Zhang, Geng, Zhou, Chen, Nie, Guo, Li, Liu, Guo, Wei, Chen: "Expression of survivin and human telomerase reverse transcriptase in extramammary Paget's disease." in: Journal of cutaneous pathology, Vol. 37, Issue 6, pp. 635-40, 2010

Images

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Supplier Images
Western Blotting (WB) image for anti-Baculoviral IAP Repeat-Containing 5 (BIRC5) (AA 121-142), (C-Term) antibody (ABIN3043195) Anti-survivin antibody, Western blotting Lane 1: HELA Cell Lysate Lane 2: JURKAT Cell...