anti-Mouse (Murine) BIRC5 antibody for ELISA

Recommended BIRC5 Antibody (supplied by: Log in to see )

Antigen
Baculoviral IAP Repeat-Containing 5 (BIRC5) Antibodies
  • API4
  • EPR-1
  • AAC-11
  • Api4
  • TIAP
  • survivin40
  • AP14
  • baculoviral IAP repeat containing 5
  • baculoviral IAP repeat-containing 5-like
  • baculoviral IAP repeat-containing 5
  • BIRC5
  • LOC696283
  • Birc5
Reactivity
Human, Mouse (Murine), Rat (Rattus)
88
35
15
Host
Rabbit
68
32
4
Clonality
Polyclonal
Conjugate
This BIRC5 antibody is un-conjugated
8
3
2
1
1
1
1
1
Application
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
79
41
25
20
14
14
6
5
4
2
2
2
1
1
1
Supplier
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Catalog No. ABIN6260270
$ 390.77
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN6102846 ELISA IF/ICC IHC Rabbit IgG pThr117 Log in to see Polyclonal 0
1 ABIN6105610 ELISA IF/ICC IHC WB Rabbit IgG Thr117 Log in to see Polyclonal 0
1 ABIN6102730 ELISA IHC Rabbit IgG Thr34 Log in to see Polyclonal 0
1 ABIN6103980 ELISA WB Rabbit IgG pThr34 Log in to see Polyclonal 0
1 ABIN2428785 IHC ELISA WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2909854 ELISA Biotin Rabbit IgG AA 1-140 Log in to see Polyclonal 0
1 ABIN2909323 ELISA FITC Rabbit IgG AA 1-140 Log in to see Polyclonal 0
1 ABIN2909324 ELISA HRP Rabbit IgG AA 1-140 Log in to see Polyclonal 0
1 ABIN2909320 ELISA IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2909325 ELISA Rabbit IgG AA 1-140 Log in to see Polyclonal 0
1 ABIN6042838 ELISA IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN6042534 ELISA IHC Rabbit IgG Log in to see Polyclonal 0
1 ABIN2421277 IHC ELISA Rabbit IgG Log in to see Polyclonal 0
1 ABIN6102872 ELISA IHC Rabbit IgG Log in to see Polyclonal 0
1 ABIN5926995 ELISA WB Rabbit IgG pThr117 Log in to see Polyclonal 0
1 ABIN2753394 ELISA WB Biotin Rabbit IgG AA 1-140 Log in to see Polyclonal 0
1 ABIN2753392 ELISA WB HRP Rabbit IgG AA 1-140 Log in to see Polyclonal 0
1 ABIN2753393 ELISA WB FITC Rabbit IgG AA 1-140 Log in to see Polyclonal 0
1 ABIN2753391 ELISA WB Rabbit IgG AA 1-140 Log in to see Polyclonal 0

General

Antigen Baculoviral IAP Repeat-Containing 5 (BIRC5) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(88), (35), (15)
Host Rabbit
(68), (32), (4)
Clonality
Polyclonal
Conjugate This BIRC5 antibody is un-conjugated
(8), (3), (2), (1), (1), (1), (1), (1)
Application ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
(79), (41), (25), (20), (14), (14), (6), (5), (4), (2), (2), (2), (1), (1), (1)
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Product Details anti-BIRC5 Antibody

Target Details BIRC5 Application Details Handling Images
Specificity BIRC5 Antibody detects endogenous levels of total BIRC5
Cross-Reactivity Human, Mouse (Murine), Rat (Rattus)
Purification The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
Immunogen A synthesized peptide derived from human BIRC5
Isotype IgG
Plasmids, Primers & others

Target Details BIRC5

Product Details anti-BIRC5 Antibody Application Details Handling Images back to top
Antigen
Alternative Name BIRC5 (BIRC5 Antibody Abstract)
Background

Description: Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (PubMed:9859993, PubMed:21364656, PubMed:20627126). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (PubMed:16322459). Acts as an important regulator of the localization of this complex, directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with polymerized microtubules (PubMed:20826784). Involved in the recruitment of CPC to centromeres during early mitosis via association with histone H3 phosphorylated at 'Thr-3' (H3pT3) during mitosis (PubMed:20929775). The complex with RAN plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules (PubMed:18591255). May counteract a default induction of apoptosis in G2/M phase (PubMed:9859993). The acetylated form represses STAT3 transactivation of target gene promoters (PubMed:20826784). May play a role in neoplasia (PubMed:10626797). Inhibitor of CASP3 and CASP7 (PubMed:21536684). Isoform 2 and isoform 3 do not appear to play vital roles in mitosis (PubMed:12773388, PubMed:16291752). Isoform 3 shows a marked reduction in its anti-apoptotic effects when compared with the displayed wild-type isoform (PubMed:10626797).

Gene: BIRC5

Molecular Weight 16kDa
Gene ID 332
UniProt O15392
Pathways Apoptosis, Cell Division Cycle

Application Details

Product Details anti-BIRC5 Antibody Target Details BIRC5 Handling Images back to top
Application Notes WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500
Restrictions For Research Use only

Handling

Product Details anti-BIRC5 Antibody Target Details BIRC5 Application Details Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20 °C.Stable for 12 months from date of receipt
Expiry Date 12 months