anti-Human Caspase 2 antibody for Western Blotting

Recommended Caspase 2 Antibody (supplied by: Log in to see )

Antigen
Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) Antibodies
  • xCaspase-2
  • Caspase-2
  • ICH-1
  • Nedd2
  • CASP-2
  • ICH1
  • NEDD-2
  • NEDD2
  • PPP1R57
  • ICH-1L/1S
  • ICH1L1S
  • caspase 2
  • caspase 2 L homeolog
  • caspase-2
  • CASP2
  • casp2.L
  • CpipJ_CPIJ008254
  • Casp2
Epitope
AA 417-439, C-Term
21
12
9
8
6
6
5
5
4
4
4
4
4
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Rat (Rattus)
212
103
76
12
10
2
2
2
2
2
1
1
1
1
1
1
Host
Rabbit
183
25
15
Clonality
Polyclonal
Conjugate
This Caspase 2 antibody is un-conjugated
7
7
3
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
183
90
72
35
21
17
15
13
13
6
4
4
4
Options
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Catalog No. ABIN3043696
$ 240.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.0643756 ABIN222882 IHC WB Rabbit IgG Log in to see Polyclonal 2
3.0643756 ABIN2787902 WB Rabbit Middle Region Log in to see Polyclonal 0
3.0643756 ABIN3043468 WB Rabbit IgG AA 378-409, C-Term Log in to see Polyclonal 0
3.0643756 ABIN2705678 IHC WB Rabbit Center Log in to see Polyclonal 0
3.0643756 ABIN1536101 ELISA WB Rabbit IgG AA 151-200, Cleaved-Gly170 Log in to see Polyclonal 2
3.0643756 ABIN1536102 ELISA WB Rabbit IgG AA 276-325, Cleaved-Thr325 Log in to see Polyclonal 2
3.0643756 ABIN1532667 IHC ELISA WB Rabbit IgG AA 123-172 Log in to see Polyclonal 1
3.0643756 ABIN388122 FACS IHC (p) WB Rabbit Ig Fraction AA 198-226, Center Log in to see Polyclonal 3
3.0643756 ABIN3183666 ELISA IHC WB Rabbit IgG Ser197 Log in to see Polyclonal 0
3.0643756 ABIN180742 EIA WB Mouse IgG2b AA 32-169 Log in to see 1C10 0
3.0643756 ABIN5951607 FACS ICC IF IHC IHC (p) WB Rabbit IgG AA 150-350 Log in to see SR44-01 0
3.0643756 ABIN4288070 WB Rabbit IgG Center Log in to see Polyclonal 0
3.0643756 ABIN2976269 IHC WB Rabbit IgG Log in to see Polyclonal 0
3.0643756 ABIN4288071 ELISA ICC IF WB Rabbit N-Term Log in to see Polyclonal 0
3.0643756 ABIN252631 WB Mouse IgM kappa Log in to see 18E809-3 0
3.0643756 ABIN4903135 FACS IHC WB Rabbit IgG Log in to see Polyclonal 0
3.0643756 ABIN5960790 ELISA IHC (p) WB Rabbit IgG Ser157 Log in to see Polyclonal 0
3.0643756 ABIN1077908 ICC IHC WB Rabbit IgG AA 334-452 Log in to see Polyclonal 0
3.0643756 ABIN5996926 IF/ICC IHC WB Rabbit IgG Log in to see 0
3.0643756 ABIN1539971 WB Mouse IgG1 AA 432-461 Log in to see 550CT8-5-2 0

General

Antigen Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) Antibodies
Epitope AA 417-439, C-Term
(21), (12), (9), (8), (6), (6), (5), (5), (4), (4), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Rat (Rattus)
(212), (103), (76), (12), (10), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Host Rabbit
(183), (25), (15)
Clonality
Polyclonal
Conjugate This Caspase 2 antibody is un-conjugated
(7), (7), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Western Blotting (WB)
(183), (90), (72), (35), (21), (17), (15), (13), (13), (6), (4), (4), (4)
Pubmed 27 references available
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Product Details anti-Caspase 2 Antibody

Target Details Caspase 2 Application Details Handling References for anti-Caspase 2 antibody (ABIN3043696) Images
Purpose Rabbit IgG polyclonal antibody for Caspase-2(CASP2) detection. Tested with WB in Human,Mouse,Rat.
Sequence REGYAPGTEF HRCKEMSEYC STL
Cross-Reactivity (Details) Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
Characteristics Rabbit IgG polyclonal antibody for Caspase-2(CASP2) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: caspase 2, apoptosis-related cysteine peptidase
Protein Name: Caspase-2(CASP-2)
Purification Immunogen affinity purified.
Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of human Caspase-2(417-439aa REGYAPGTEFHRCKEMSEYCSTL), identical to the related rat and mouse sequences.
Isotype IgG
Plasmids, Primers & others

Target Details Caspase 2

Product Details anti-Caspase 2 Antibody Application Details Handling References for anti-Caspase 2 antibody (ABIN3043696) Images back to top
Antigen
Alternative Name CASP2 (CASP2 Antibody Abstract)
Background Caspase-2, which is involved in stress-induced apoptosis, is recruited into a large protein complex, the molecular composition of which remains elusive. activation of caspase-2 occurs in a complex that contains the death domain-containing protein PIDD, whose expression is induced by p53, and the adaptor protein RAIDD. Increased PIDD expression resulted in spontaneous activation of caspase-2 and sensitization to apoptosis by genotoxic stimuli. Caspase-2 acts both as a positive and negative cell death effector, depending upon cell lineage and stage of development.

Synonyms: Apoptosis related cysteine peptidase antibody|CASP 2 antibody|Casp 2L Pro antibody|CASP-2 antibody|CASP2 antibody|CASP2_HUMAN antibody|Caspase 2 apoptosis related cysteine protease antibody|Caspase-2 subunit p12 antibody|Caspase2 antibody|Developmentally down regulated 2 antibody|ICH 1 antibody|ICH 1 protease antibody|ICH 1L antibody|ICH 1L/1S antibody|ICH1 antibody|ICH1 protease antibody|ICH1L antibody|ICH1L/1S antibody|NEDD 2 antibody|NEDD-2 antibody|NEDD2 antibody|NEDD2 apoptosis regulatory gene antibody|Neural precursor cell expressed antibody|Neural precursor cell expressed developmentally down regulated 2 antibody|Neural precursor cell expressed developmentally down-regulated protein 2 antibody|Protease ICH-1 antibody
UniProt P42575
Pathways Apoptosis, Caspase Cascade in Apoptosis, Neurotrophin Signaling Pathway

Application Details

Product Details anti-Caspase 2 Antibody Target Details Caspase 2 Handling References for anti-Caspase 2 antibody (ABIN3043696) Images back to top
Application Notes WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.
Comment

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions For Research Use only

Handling

Product Details anti-Caspase 2 Antibody Target Details Caspase 2 Application Details References for anti-Caspase 2 antibody (ABIN3043696) Images back to top
Format Lyophilized
Reconstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Concentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
Preservative Thimerosal (Merthiolate), Sodium azide
Precaution of Use This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

References for anti-Caspase 2 antibody (ABIN3043696)

Product Details anti-Caspase 2 Antibody Target Details Caspase 2 Application Details Handling Images back to top
Product cited in:

Kan, Zhou, Jin, Yang: "Effects of PDTC on NF-?B expression and apoptosis in rats with severe acute pancreatitis-associated lung injury." in: International journal of clinical and experimental medicine, Vol. 8, Issue 3, pp. 3258-70, 2015

Xu, Liu, Zhang, Wang, Wang, Yang, Huo, Sun: "Apoptosis-related protein expression in rabbits with blast brain injury following early hyperbaric oxygen therapy." in: Neural regeneration research, Vol. 7, Issue 17, pp. 1318-24, 2015

Ding, Wang, Zhao, Sun, Zhai: "Protective Effects of Baicalin on A?????-Induced Learning and Memory Deficit, Oxidative Stress, and Apoptosis in Rat." in: Cellular and molecular neurobiology, Vol. 35, Issue 5, pp. 623-32, 2015

Yang, Li, Liu, Shi, Zhang: "Inhibitory effect of tetramethylpyrazine preconditioning on overload training-induced myocardial apoptosis in rats." in: Chinese journal of integrative medicine, Vol. 21, Issue 6, pp. 423-30, 2015

Li, Wang, Wang: "Radioprotective activity of neutral polysaccharides isolated from the fruiting bodies of Hohenbuehelia serotina." in: Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB), Vol. 31, Issue 4, pp. 352-9, 2015

Zhan, Hu, Yi, An, Huang: "Inhibitory activity of apogossypol in human prostate cancer in vitro and in vivo." in: Molecular medicine reports, Vol. 11, Issue 6, pp. 4142-8, 2015

Peng, Chen, Chen, Fang, Cui, Zuo, Deng, Chen, Geng, Lai: "Aflatoxin B1 affects apoptosis and expression of Bax, Bcl-2, and Caspase-3 in thymus and bursa of fabricius in broiler chickens." in: Environmental toxicology, 2015

Huang, Lin, Su, Ye: "Forsythiaside protects against hydrogen peroxide-induced oxidative stress and apoptosis in PC12 cell." in: Neurochemical research, Vol. 40, Issue 1, pp. 27-35, 2015

Jiang, Li, Zhou, Wang, Zhang, Wang: "Colistin-induced apoptosis in PC12 cells: involvement of the mitochondrial apoptotic and death receptor pathways." in: International journal of molecular medicine, Vol. 33, Issue 5, pp. 1298-304, 2014

Yan, Liang, Zhang, Liu, Bu: "Apoptotic induction of lung adenocarcinoma A549 cells infected by recombinant RVG Newcastle disease virus (rL-RVG) in vitro." in: Molecular medicine reports, Vol. 11, Issue 1, pp. 317-26, 2014

Wei, Tian, Yan, Shao, Xie: "Protective effects of phillyrin on H2O 2-induced oxidative stress and apoptosis in PC12 cells." in: Cellular and molecular neurobiology, Vol. 34, Issue 8, pp. 1165-73, 2014

Mao, Song, Li, Lv, Zhao, Li, Feng, Chen: "8-hydroxy-2-(di-n-propylamino)tetralin intervenes with neural cell apoptosis following diffuse axonal injury." in: Neural regeneration research, Vol. 8, Issue 2, pp. 133-42, 2014

Tian, Wei, Li, Wang, Zhang, Xie: "Pathway of programmed cell death and oxidative stress induced by ?-hydroxybutyrate in dairy cow abomasum smooth muscle cells and in mouse gastric smooth muscle." in: PLoS ONE, Vol. 9, Issue 5, pp. e96775, 2014

Song, Wang, Chen, Zhang, Wang, Liu, Gao, Yan: "Toxic effects of sodium fluoride on cell proliferation and apoptosis of Leydig cells from young mice." in: Journal of physiology and biochemistry, Vol. 70, Issue 3, pp. 761-8, 2014

Dong, Wang: "Antitumor effects of artesunate on human breast carcinoma MCF-7 cells and IGF-IR expression in nude mice xenografts." in: Chinese journal of cancer research = Chung-kuo yen cheng yen chiu, Vol. 26, Issue 2, pp. 200-7, 2014

Zhao, Li: "Altholactone induces reactive oxygen species-mediated apoptosis in bladder cancer T24 cells through mitochondrial dysfunction, MAPK-p38 activation and Akt suppression." in: Oncology reports, Vol. 31, Issue 6, pp. 2769-75, 2014

Khan, Li, Ahmad Khan, Rasul, Nawaz, Sun, Zheng, Ma: "Alantolactone induces apoptosis in HepG2 cells through GSH depletion, inhibition of STAT3 activation, and mitochondrial dysfunction." in: BioMed research international, Vol. 2013, pp. 719858, 2013

Chen, Shu, Peng, Fang, Cui, Chen, Wang, Chen, Zuo, Deng, Geng, Lai: "Protective role of sodium selenite on histopathological lesions, decreased T-cell subsets and increased apoptosis of thymus in broilers intoxicated with aflatoxin B?." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 59, pp. 446-54, 2013

Chen, Li, Qiu, You, Zhang, Dong, Zuo: "Kinetics of apoptosis and expression of apoptosis-related proteins in rat CA3 hippocampus cells after experimental diffuse brain injury." in: Cell biochemistry and biophysics, Vol. 67, Issue 3, pp. 1015-9, 2013

Rasul, Yu, Khan, Zhang, Iqbal, Ma, Yang: "Magnolol, a natural compound, induces apoptosis of SGC-7901 human gastric adenocarcinoma cells via the mitochondrial and PI3K/Akt signaling pathways." in: International journal of oncology, Vol. 40, Issue 4, pp. 1153-61, 2012

Images

Product Details anti-Caspase 2 Antibody Target Details Caspase 2 Application Details Handling References for anti-Caspase 2 antibody (ABIN3043696) back to top
Supplier Images
Western Blotting (WB) image for anti-Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) (AA 417-439), (C-Term) antibody (ABIN3043696) Anti-Caspase-2 antibody, Western blotting Lane 1: CEM Cell Lysate Lane 2: SMMC Cell L...