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Caspase 2 Proteins

(Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011].
Caspase 2 Protein (AA 121-220) (GST tag) Caspase 2 Protein (AA 121-220) (GST tag) Caspase 2 Protein (AA 121-220) (GST tag) (ABIN1348098)

CASP2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

Caspase 2 Protein (AA 1-452) (GST tag) Caspase 2 Protein (AA 1-452) (GST tag) Caspase 2 Protein (AA 1-452) (GST tag) (ABIN1348097)

CASP2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

Caspase 2 Protein (AA 348-452) (His tag) Caspase 2 Protein (AA 348-452) (His tag) Caspase 2 Protein (AA 348-452) (His tag) (ABIN3090918)

Crystallography grade CASP2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys

Caspase 2 Proteins by Grade

Find Caspase 2 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

Caspase 2 Proteins by Origin

Find Caspase 2 Proteins for a variety of species such as anti-Human Caspase 2, anti-Mouse Caspase 2, anti-Chicken Caspase 2. The species listed below are among those available. Click on a link to go to the corresponding products.

Caspase 2 Proteins by Source

Here you will find Caspase 2 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Caspase 2 Proteins by Protein Type

Here you can find Caspase 2 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

Caspase 2 Proteins by Application

Find Caspase 2 Proteins validated for a specific application such as SDS, WB, ELISA, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Caspase 2 Proteins by Biological Activity

Find Caspase 2 Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular Caspase 2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348098
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348097
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3090918
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3090917
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3090916
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3133630
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3133629
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3133628
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7419970
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7405921
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7389635
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5709201
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5853713
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN925026
Quantity 25 U
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1474821
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Caspase 2 Proteins

Murakami, Tolstykh, Bao, Niu, Steuer, Bao, Chang, Espiritu, Bansal, Lam, Otto, Sofia, Furman: "Mechanism of activation of PSI-7851 and its diastereoisomer PSI-7977." in: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 34337-47, (2010) (PubMed).

Chen, Xia, Fang, Hawke, Lu: "Caspase-10-mediated heat shock protein 90 beta cleavage promotes UVB irradiation-induced cell apoptosis." in: Molecular and cellular biology, Vol. 29, Issue 13, pp. 3657-64, (2009) (PubMed).

Hasegawa, Yamada, Komiyama, Hayashi, Ishibashi, Sunazuka, Izuhara, Sugahara, Tsuruda, Masuda, Takasu, Tsukasaki, Tomonaga, Kamihira et al.: "A novel natural compound, a cycloanthranilylproline derivative (Fuligocandin B), sensitizes leukemia cells to apoptosis induced by tumor necrosis factor related apoptosis-inducing ligand (TRAIL) ..." in: Blood, Vol. 110, Issue 5, pp. 1664-74, (2007) (PubMed).

Basu, Lu, Sun, Moor, Akkaraju, Huang: "Proteolytic activation of protein kinase C-epsilon by caspase-mediated processing and transduction of antiapoptotic signals." in: The Journal of biological chemistry, Vol. 277, Issue 44, pp. 41850-6, (2002) (PubMed).

Aliases for Caspase 2 Proteins

caspase 2 (CASP2) Proteins
caspase 2 L homeolog (casp2.L) Proteins
caspase-2 (CpipJ_CPIJ008254) Proteins
caspase 2 (Casp2) Proteins
CASP-2 Proteins
Caspase-2 Proteins
ICH-1 Proteins
ICH-1L/1S Proteins
ICH1 Proteins
ICH1L1S Proteins
NEDD-2 Proteins
Nedd2 Proteins
NEDD2 Proteins
PPP1R57 Proteins
xCaspase-2 Proteins
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