anti-Rat (Rattus) Caspase 4 antibody for ELISA
Recommended Caspase 4 Antibody (supplied by: Log in to see )
- Antigen
-
Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) Antibodies
show synonyms for this antigen- ICE(rel)II
- ICEREL-II
- ICH-2
- Mih1/TX
- TX
- Casp11
- CASP13
- CASP1
- CASP4
- Caspl
- ich-3
- Casp4
- caspase 4
- caspase 4, apoptosis-related cysteine peptidase
- caspase-4
- CASP4
- Casp4
- LOC100731032
- Reactivity
-
Mouse (Murine), Rat (Rattus)
Alternatives - Host
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Rat
Alternatives - Clonality
- Conjugate
-
This Caspase 4 antibody is un-conjugated
Alternatives - Application
-
Flow Cytometry (FACS), Immunoprecipitation (IP), ELISA, Western Blotting (WB)
Alternatives - Options
- Supplier
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- Supplier Product No.
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Catalog No. ABIN2745522
$ 408.25
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| Relevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ABIN2745523 | FACS IP ELISA WB | Rat | IgG1 | Log in to see | 4-00E-11 | 0 | |||
| 1 | ABIN1453020 | IHC ELISA WB | Rabbit | IgG | AA 75-124 | Log in to see | Polyclonal | 0 | ||
| 1 | ABIN3183668 | ELISA IHC WB | Rabbit | IgG | Internal Region | Log in to see | Polyclonal | 0 | ||
| 1 | ABIN5690634 | ELISA FACS IP WB | Rat | IgG1, kappa | Log in to see | 4E11 | 0 | |||
| 1 | ABIN5690635 | ELISA FACS IP WB | Rat | IgG1, kappa | Log in to see | 8A5 | 0 | |||
| 1 | ABIN2617982 | ELISA FACS IP WB | Rat | IgG1, kappa | Log in to see | 4E11 | 0 | |||
| 1 | ABIN2617983 | ELISA FACS IP WB | Rat | IgG1, kappa | Log in to see | 8A5 | 0 | |||
| 1 | ABIN2885852 | IHC ELISA WB | Rabbit | IgG | AA 75-124 | Log in to see | Polyclonal | 0 | ||
| 1 | ABIN5693194 | ELISA WB | Rabbit | AA 108-195 | Log in to see | Polyclonal | 0 | |||
| 1 | ABIN6104823 | ELISA IHC WB | Rabbit | IgG | Internal Region | Log in to see | Polyclonal | 0 |
General |
|
|---|---|
| Antigen | Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) Antibodies |
| Reactivity | Mouse (Murine), Rat (Rattus) Alternatives |
| Host | Rat Alternatives |
| Clonality (Clone) | |
| Conjugate | This Caspase 4 antibody is un-conjugated Alternatives |
| Application |
Flow Cytometry (FACS), Immunoprecipitation (IP), ELISA, Western Blotting (WB)
Alternatives
|
| Supplier | Log in to see |
Product Details anti-Caspase 4 AntibodyTarget Details Caspase 4 Application Details Handling Images |
|
| Specificity | Recognizes mouse and rat full-length caspase-11 protein. Detects two bands of ~38 kDa and ~43 kDa by Western blot. |
| Cross-Reactivity | Mouse (Murine), Rat (Rattus) |
| Purity | >95 % (SDS-PAGE) |
| Endotoxin Level | <0.1EU/μg purified protein (LAL test, Lonza). |
| Immunogen | Recombinant mouse caspase-11 (p20 fragment). |
| Clone | 8A5 |
| Isotype | IgG1 |
| Plasmids, Primers & others | |
Target Details Caspase 4Product Details anti-Caspase 4 Antibody Application Details Handling Images back to top |
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| Antigen | |
| Alternative Name | Caspase-11 (CASP4 Antibody Abstract) |
| Background | Caspase-11 not only activates caspase-1, that is required for the maturation of proinflammatory cytokines such as interleukin-1 (IL-1) and interleukin-18 (IL-18), but also activates caspase-3, leading to cellular apoptosis under pathological conditions. In most cells, caspase-11 is only expressed upon induction with pro-inflammatory stimuli. Caspase-11 is an essential mediator of endotoxic shock and caspase-11-deficient mice are resistant to endotoxic shock. LPS-induced caspase-11 regulates lymphocyte apoptosis by activating both caspase-3 and caspase-7. |
| UniProt | P70343 |
| Pathways | Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity |
Application DetailsProduct Details anti-Caspase 4 Antibody Target Details Caspase 4 Handling Images back to top |
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| Application Notes | Optimal working dilution should be determined by the investigator. |
| Restrictions | For Research Use only |
HandlingProduct Details anti-Caspase 4 Antibody Target Details Caspase 4 Application Details Images back to top |
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| Format | Liquid |
| Concentration | 1 mg/mL |
| Buffer | In PBS containing 0.02 % sodium azide. |
| Preservative | Sodium azide |
| Precaution of Use | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Storage | 4 °C,-20 °C |
| Storage Comment |
Short Term Storage: +4°C Long Term Storage: -20°C Stable for at least 1 year after receipt when stored at -20°C. |
| Expiry Date | 12 months |
ImagesProduct Details anti-Caspase 4 Antibody Target Details Caspase 4 Application Details Handling back to top |
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| Supplier Images |
Immunoprecipitation of caspase-11 using anti-caspase-11 mAbs (4E11 and 8A5)
Flow cytometry data of overexpressed FLAG-tagged caspase-11 in 293T cells using anti-...
Western blot using anti-Caspase-11 (mouse), mAb (8A5) detecting endogenous caspase-1...
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