anti-Rat (Rattus) Caspase 4 antibody for Western Blotting

Recommended Caspase 4 Antibody (supplied by: Log in to see )

Antigen
Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) Antibodies
  • ICE(rel)II
  • ICEREL-II
  • ICH-2
  • Mih1/TX
  • TX
  • Casp11
  • CASP13
  • CASP1
  • CASP4
  • Caspl
  • ich-3
  • Casp4
  • caspase 4
  • caspase 4, apoptosis-related cysteine peptidase
  • caspase-4
  • CASP4
  • Casp4
  • LOC100731032
Reactivity
Mouse (Murine), Rat (Rattus)
207
103
41
21
3
1
1
Host
Rat
204
27
19
18
7
Clonality
Monoclonal
Conjugate
This Caspase 4 antibody is un-conjugated
18
15
4
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunoprecipitation (IP), ELISA, Western Blotting (WB)
264
100
99
55
31
25
19
17
17
9
3
2
2
2
1
Options
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Available images

Catalog No. ABIN2745522
$ 501.44
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
22.563524 ABIN2745523 FACS IP ELISA WB Rat IgG1 Log in to see 4-00E-11 0
12.811565 ABIN3183668 ELISA IHC WB Rabbit IgG Internal Region Log in to see Polyclonal 0
12.811565 ABIN5621373 WB Rabbit Log in to see Polyclonal 0
12.811565 ABIN2135448 WB Rabbit IgG Log in to see Polyclonal 0
10.751959 ABIN6260482 ELISA IHC WB Rabbit IgG Log in to see Polyclonal 0
10.751959 ABIN6260486 ELISA ICC IF IHC WB Rabbit IgG Log in to see Polyclonal 0
9.251959 ABIN222879 WB Rabbit IgG Log in to see Polyclonal 1
9.251959 ABIN222883 WB Rabbit IgG Log in to see Polyclonal 1
7.751959 ABIN2787904 WB Rabbit Middle Region Log in to see Polyclonal 0
7.751959 ABIN498677 IHC (p) WB Rabbit Log in to see Polyclonal 0
7.751959 ABIN5693194 ELISA WB Rabbit AA 108-195 Log in to see Polyclonal 0
7.751959 ABIN1031750 IHC ELISA WB Rabbit Log in to see Polyclonal 0
4.751959 ABIN6570485 WB Rabbit IgG Log in to see Polyclonal 0
4.751959 ABIN920756 WB Rabbit IgG Log in to see Polyclonal 0
4 ABIN126967 WB Rabbit Log in to see Polyclonal 0
4 ABIN241603 WB Rabbit Log in to see Polyclonal 0
4 ABIN241609 WB Rabbit Log in to see Polyclonal 0
1 ABIN1001995 WB Rabbit Log in to see Polyclonal 0
1 ABIN1453020 IHC ELISA WB Rabbit IgG AA 75-124 Log in to see Polyclonal 0
1 ABIN1002002 IHC ELISA WB Rabbit IgG Log in to see Polyclonal 1

General

Antigen Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) Antibodies
Reactivity Mouse (Murine), Rat (Rattus)
(207), (103), (41), (21), (3), (1), (1)
Host Rat
(204), (27), (19), (18), (7)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Caspase 4 antibody is un-conjugated
(18), (15), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunoprecipitation (IP), ELISA, Western Blotting (WB)
(264), (100), (99), (55), (31), (25), (19), (17), (17), (9), (3), (2), (2), (2), (1)
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Product Details anti-Caspase 4 Antibody

Target Details Caspase 4 Application Details Handling Images
Specificity Recognizes mouse and rat full-length caspase-11 protein. Detects two bands of ~38 kDa and ~43 kDa by Western blot.
Cross-Reactivity Mouse (Murine), Rat (Rattus)
Purity >95 % (SDS-PAGE)
Endotoxin Level <0.1EU/μg purified protein (LAL test, Lonza).
Immunogen Recombinant mouse caspase-11 (p20 fragment).
Clone 8A5
Isotype IgG1
Plasmids, Primers & others

Target Details Caspase 4

Product Details anti-Caspase 4 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Caspase-11 (CASP4 Antibody Abstract)
Background Caspase-11 not only activates caspase-1, that is required for the maturation of proinflammatory cytokines such as interleukin-1 (IL-1) and interleukin-18 (IL-18), but also activates caspase-3, leading to cellular apoptosis under pathological conditions. In most cells, caspase-11 is only expressed upon induction with pro-inflammatory stimuli. Caspase-11 is an essential mediator of endotoxic shock and caspase-11-deficient mice are resistant to endotoxic shock. LPS-induced caspase-11 regulates lymphocyte apoptosis by activating both caspase-3 and caspase-7.
UniProt P70343
Pathways Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-Caspase 4 Antibody Target Details Caspase 4 Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-Caspase 4 Antibody Target Details Caspase 4 Application Details Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer In PBS containing 0.02 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.
Expiry Date 12 months

Images

Product Details anti-Caspase 4 Antibody Target Details Caspase 4 Application Details Handling back to top
Supplier Images
Immunoprecipitation (IP) image for anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) antibody (ABIN2745522) Immunoprecipitation of caspase-11 using anti-caspase-11 mAbs (4E11 and 8A5)
Flow Cytometry (FACS) image for anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) antibody (ABIN2745522) Flow cytometry data of overexpressed FLAG-tagged caspase-11 in 293T cells using anti-...
Western Blotting (WB) image for anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) antibody (ABIN2745522) Western blot using anti-Caspase-11 (mouse), mAb (8A5) detecting endogenous caspase-1...