anti-Cynomolgus CD11b antibody for Functional Studies

Recommended CD11b Antibody (supplied by: Log in to see )

Antigen
Integrin alpha M (ITGAM) Antibodies
  • CD11b/CD18
  • CR3
  • CR3A
  • Cd11b
  • F730045J24Rik
  • Ly-40
  • MAC1
  • Mac-1
  • Mac-1a
  • CD11B
  • MAC-1
  • MAC1A
  • MO1A
  • SLEB6
  • C3bi
  • integrin, alpha M (complement component 3 receptor 3 subunit)
  • integrin alpha M
  • integrin, alpha M
  • ITGAM
  • Itgam
Reactivity
Baboon, Chimpanzee, Cynomolgus, Human, Mouse (Murine), Rabbit, Rhesus Monkey
732
514
192
78
31
19
16
14
12
11
10
9
8
7
5
4
4
4
3
2
Host
Rat
533
409
168
17
6
2
Clonality
Monoclonal
Conjugate
This CD11b antibody is un-conjugated
150
128
94
56
24
24
20
17
15
14
14
13
13
13
11
11
11
10
9
7
7
6
6
6
6
6
4
4
4
4
4
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Blocking Reagent (BR), ELISA, Flow Cytometry (FACS), Functional Studies (Func), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)
930
237
235
172
172
137
100
98
96
67
25
21
20
18
14
8
5
5
4
3
3
1
1
1
1
1
1
1
1
1
Supplier
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Catalog No. ABIN2742255
$ 595.83
Plus shipping costs $45.00

General

Antigen Integrin alpha M (ITGAM) Antibodies
Reactivity Baboon, Chimpanzee, Cynomolgus, Human, Mouse (Murine), Rabbit, Rhesus Monkey
(732), (514), (192), (78), (31), (19), (16), (14), (12), (11), (10), (9), (8), (7), (5), (4), (4), (4), (3), (2)
Host Rat
(533), (409), (168), (17), (6), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD11b antibody is un-conjugated
(150), (128), (94), (56), (24), (24), (20), (17), (15), (14), (14), (13), (13), (13), (11), (11), (11), (10), (9), (7), (7), (6), (6), (6), (6), (6), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application Blocking Reagent (BR), ELISA, Flow Cytometry (FACS), Functional Studies (Func), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)
(930), (237), (235), (172), (172), (137), (100), (98), (96), (67), (25), (21), (20), (18), (14), (8), (5), (5), (4), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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Product Details anti-CD11b Antibody

Target Details CD11b Application Details Handling Images
Specificity Mouse ITGAM / CD11b
Purification Protein G purified
Immunogen B10 mouse spleen cells enriched for T lymphocytes.

Type of Immunogen: Cells
Clone M1-70
Isotype IgG2b, kappa

Target Details CD11b

Product Details anti-CD11b Antibody Application Details Handling Images back to top
Antigen
Alternative Name ITGAM / CD11b (ITGAM Antibody Abstract)
Background Name/Gene ID: ITGAM
Family: Integrin

Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain
Gene ID 3684
Pathways Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation

Application Details

Product Details anti-CD11b Antibody Target Details CD11b Handling Images back to top
Application Notes Approved: Block, ELISA, Flo (0.5 - 1 μg/10 x106), Func, IF (0.5 - 1 μg/mL), IHC-Fr (0.5 - 1 μg/mL), IP

Usage: CD11b is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin alpha-M (CD11b) combines with the Integrin beta-2 (CD18) to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin alpha-M/beta-2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. ELISA: Order BSA-free antibody format for coating.
Restrictions For Research Use only

Handling

Product Details anti-CD11b Antibody Target Details CD11b Application Details Images back to top
Format Liquid
Concentration Lot specific
Buffer PBS, pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 2-8°C.