anti-Human CD11b antibody for Enzyme Immunoassay

Recommended CD11b Antibody (supplied by: Log in to see )

Antigen
Integrin alpha M (ITGAM) Antibodies
  • CD11b/CD18
  • CR3
  • CR3A
  • Cd11b
  • F730045J24Rik
  • Ly-40
  • MAC1
  • Mac-1
  • Mac-1a
  • CD11B
  • MAC-1
  • MAC1A
  • MO1A
  • SLEB6
  • C3bi
  • integrin subunit alpha M
  • integrin alpha M
  • integrin, alpha M (complement component 3 receptor 3 subunit)
  • integrin alpha-M
  • ITGAM
  • Itgam
  • LOC100351865
Epitope
AA 256-286, N-Term
39
19
19
16
14
13
9
8
8
7
7
6
5
5
5
5
4
4
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Reactivity
Human
762
506
176
109
38
34
32
25
15
13
10
10
9
8
6
5
4
4
2
2
Host
Rabbit
540
417
160
17
5
2
Clonality
Polyclonal
Conjugate
This CD11b antibody is un-conjugated
146
127
97
64
19
17
17
16
14
14
14
13
12
11
9
9
9
8
8
7
6
6
5
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
937
276
226
200
169
169
91
91
90
61
26
21
13
13
9
8
5
5
4
3
3
1
1
1
1
1
1
1
1
1
1
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Catalog No. ABIN951175
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5553276 EIA IHC (p) WB Goat Internal Region Log in to see Polyclonal 0

General

Antigen Integrin alpha M (ITGAM) Antibodies
Epitope AA 256-286, N-Term
(39), (19), (19), (16), (14), (13), (9), (8), (8), (7), (7), (6), (5), (5), (5), (5), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Human
(762), (506), (176), (109), (38), (34), (32), (25), (15), (13), (10), (10), (9), (8), (6), (5), (4), (4), (2), (2)
Host Rabbit
(540), (417), (160), (17), (5), (2)
Clonality
Polyclonal
Conjugate This CD11b antibody is un-conjugated
(146), (127), (97), (64), (19), (17), (17), (16), (14), (14), (14), (13), (12), (11), (9), (9), (9), (8), (8), (7), (6), (6), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(937), (276), (226), (200), (169), (169), (91), (91), (90), (61), (26), (21), (13), (13), (9), (8), (5), (5), (4), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-CD11b Antibody

Target Details CD11b Application Details Handling References for anti-CD11b antibody (ABIN951175) Images
Specificity This antibody reacts to CD11b.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Immunogen KLH conjugated synthetic peptide between 256-286 amino acids from the N-terminal region of human CD11b
Isotype Ig Fraction
Plasmids, Primers & others

Target Details CD11b

Product Details anti-CD11b Antibody Application Details Handling References for anti-CD11b antibody (ABIN951175) Images back to top
Antigen
Alternative Name CD11b (ITGAM Antibody Abstract)
Background CD11b is the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.Synonyms: CD11 antigen-like family member B, CR-3 alpha chain, CR3A, Cell surface glycoprotein MAC-1 subunit alpha, ITGAM, Integrin alpha-M, Leukocyte adhesion receptor MO1, MAC1, Neutrophil adherence receptor
Molecular Weight 127179 Da
Gene ID 3684
NCBI Accession NP_000623
Pathways Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation

Application Details

Product Details anti-CD11b Antibody Target Details CD11b Handling References for anti-CD11b antibody (ABIN951175) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CD11b Antibody Target Details CD11b Application Details References for anti-CD11b antibody (ABIN951175) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-CD11b antibody (ABIN951175)

Product Details anti-CD11b Antibody Target Details CD11b Application Details Handling Images back to top
Background publications

Gjelstrup, Boesen, Kragstrup, Jørgensen, Klein, Thiel, Deleuran, Vorup-Jensen: "Shedding of large functionally active CD11/CD18 Integrin complexes from leukocyte membranes during synovial inflammation distinguishes three types of arthritis through differential epitope exposure." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 7, pp. 4154-68, 2010

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010

Images

Product Details anti-CD11b Antibody Target Details CD11b Application Details Handling References for anti-CD11b antibody (ABIN951175) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Integrin alpha M (ITGAM) (AA 256-286), (N-Term) antibody (ABIN951175) CD11b Antibody (N-term) flow cytometric analysis of Jurkat cells (right histogr...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Integrin alpha M (ITGAM) (AA 256-286), (N-Term) antibody (ABIN951175) CD11b antibody (N-term) immunohistochemistry analysis in formalin fixed and par...
Western Blotting (WB) image for anti-Integrin alpha M (ITGAM) (AA 256-286), (N-Term) antibody (ABIN951175) CD11b Antibody (N-term) western blot analysis in A549,K562 cell line lysates (3...