anti-Human CD11b antibody for Flow Cytometry

Recommended CD11b Antibody (supplied by: Log in to see )

Antigen
Integrin alpha M (ITGAM) Antibodies
  • CD11b/CD18
  • CR3
  • CR3A
  • Cd11b
  • F730045J24Rik
  • Ly-40
  • MAC1
  • Mac-1
  • Mac-1a
  • CD11B
  • MAC-1
  • MAC1A
  • MO1A
  • SLEB6
  • C3bi
  • integrin subunit alpha M
  • integrin alpha M
  • integrin, alpha M (complement component 3 receptor 3 subunit)
  • integrin alpha-M
  • ITGAM
  • Itgam
  • LOC100351865
Epitope
AA 256-286, N-Term
48
24
21
19
16
14
12
8
6
6
6
5
5
5
4
4
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Human
688
479
176
80
31
19
17
15
13
11
10
9
7
7
5
4
4
4
2
2
Host
Rabbit
506
391
151
16
5
2
Clonality
Polyclonal
Conjugate
This CD11b antibody is un-conjugated
149
123
91
62
19
18
15
15
14
14
14
13
12
11
9
8
7
7
7
6
6
6
6
6
6
4
4
4
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
870
236
228
174
165
138
97
96
95
68
21
21
14
13
12
8
5
5
4
3
3
1
1
1
1
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

Catalog No. ABIN951175
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
13.763215 ABIN258322 ICC FACS IF IHC (p) IHC WB Rabbit Internal Region, AA 500-600 Log in to see Polyclonal 16
13.763215 ABIN118517 Func FACS IHC (fro) IP Mouse IgG1 Log in to see ICRF44 4
13.763215 ABIN730918 FACS IF (p) IHC (p) WB Rabbit IgG AA 50-100 Log in to see Polyclonal 8
13.763215 ABIN4895863 FACS APC Mouse IgG2b AA 17-1105 Log in to see 238446 2
13.763215 ABIN4895864 FACS APC Mouse IgG2b AA 17-1105 Log in to see 238446 2
13.763215 ABIN4895871 FACS PE Mouse IgG2b AA 17-1105 Log in to see 238446 1
13.763215 ABIN4895872 FACS PE Mouse IgG2b AA 17-1105 Log in to see 238446 1
13.763215 ABIN4899289 CyTOF FACS WB Goat IgG AA 17-1105 Log in to see Polyclonal 1
13.763215 ABIN120130 FACS IHC (fro) IF IP Rat IgG2b Log in to see 5C6 13
13.763215 ABIN118147 FACS PE Rat IgG2b Log in to see M1-70-15 7
13.763215 ABIN118142 FACS FITC Rat IgG2b Log in to see M1-70-15 7
13.763215 ABIN118143 FACS FITC Rat IgG2b Log in to see M1-70-15 6
13.763215 ABIN118513 FACS IHC (fro) IP Mouse IgG1 Log in to see ICRF44 4
13.763215 ABIN4900696 CyTOF FACS ICC IHC Mouse IgG1 Log in to see ICRF44 3
13.763215 ABIN192410 Func FACS Mouse IgG1 Log in to see MEM-170 3
13.763215 ABIN264315 FACS PE Mouse IgG2a Log in to see F6-2 5
13.763215 ABIN2478237 FACS PE Rat IgG2b Log in to see M1-70-15 4
13.763215 ABIN2660632 FACS APC-Cy7 Rat IgG2b kappa Log in to see M1-70 11
13.763215 ABIN2660916 FACS Biotin Mouse IgG1 kappa Log in to see ICRF44 7
13.763215 ABIN2663957 FACS PE Rat IgG2b kappa Log in to see M1-70 8

General

Antigen Integrin alpha M (ITGAM) Antibodies
Epitope AA 256-286, N-Term
(48), (24), (21), (19), (16), (14), (12), (8), (6), (6), (6), (5), (5), (5), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(688), (479), (176), (80), (31), (19), (17), (15), (13), (11), (10), (9), (7), (7), (5), (4), (4), (4), (2), (2)
Host Rabbit
(506), (391), (151), (16), (5), (2)
Clonality
Polyclonal
Conjugate This CD11b antibody is un-conjugated
(149), (123), (91), (62), (19), (18), (15), (15), (14), (14), (14), (13), (12), (11), (9), (8), (7), (7), (7), (6), (6), (6), (6), (6), (6), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(870), (236), (228), (174), (165), (138), (97), (96), (95), (68), (21), (21), (14), (13), (12), (8), (5), (5), (4), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 2 references available
Supplier Log in to see

Product Details anti-CD11b Antibody

Target Details CD11b Application Details Handling References for anti-CD11b antibody (ABIN951175) Images
Specificity This antibody reacts to CD11b.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Immunogen KLH conjugated synthetic peptide between 256-286 amino acids from the N-terminal region of human CD11b
Isotype Ig Fraction

Target Details CD11b

Product Details anti-CD11b Antibody Application Details Handling References for anti-CD11b antibody (ABIN951175) Images back to top
Antigen
Alternative Name CD11b (ITGAM Antibody Abstract)
Background CD11b is the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.Synonyms: CD11 antigen-like family member B, CR-3 alpha chain, CR3A, Cell surface glycoprotein MAC-1 subunit alpha, ITGAM, Integrin alpha-M, Leukocyte adhesion receptor MO1, MAC1, Neutrophil adherence receptor
Molecular Weight 127179 Da
Gene ID 3684
NCBI Accession NP_000623
Research Area Stem Cells, Hematopoietic Progenitors, Hematopoietic Stem Cells, Glia marker, CD Antigens, Surface Receptors of Immune Cells
Pathways Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation

Application Details

Product Details anti-CD11b Antibody Target Details CD11b Handling References for anti-CD11b antibody (ABIN951175) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CD11b Antibody Target Details CD11b Application Details References for anti-CD11b antibody (ABIN951175) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-CD11b antibody (ABIN951175)

Product Details anti-CD11b Antibody Target Details CD11b Application Details Handling Images back to top
Background publications

Gjelstrup, Boesen, Kragstrup, Jørgensen, Klein, Thiel, Deleuran, Vorup-Jensen: "Shedding of large functionally active CD11/CD18 Integrin complexes from leukocyte membranes during synovial inflammation distinguishes three types of arthritis through differential epitope exposure." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 7, pp. 4154-68, 2010

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010

Images

Product Details anti-CD11b Antibody Target Details CD11b Application Details Handling References for anti-CD11b antibody (ABIN951175) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Integrin alpha M (ITGAM) (AA 256-286), (N-Term) antibody (ABIN951175) CD11b Antibody (N-term) flow cytometric analysis of Jurkat cells (right histogr...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Integrin alpha M (ITGAM) (AA 256-286), (N-Term) antibody (ABIN951175) CD11b antibody (N-term) immunohistochemistry analysis in formalin fixed and par...
Western Blotting (WB) image for anti-Integrin alpha M (ITGAM) (AA 256-286), (N-Term) antibody (ABIN951175) CD11b Antibody (N-term) western blot analysis in A549,K562 cell line lysates (3...