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General |
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Antigen | Integrin alpha M (ITGAM) Antibodies |
Reactivity | Human, Mouse (Murine), Primate, Rabbit Alternatives |
Host | Rat Alternatives |
Clonality (Clone) | |
Conjugate | This CD11b antibody is un-conjugated Alternatives |
Application |
Blocking Reagent (BR), Flow Cytometry (FACS), Functional Studies (Func), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Neutralization (Neut)
Alternatives
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Supplier | Log in to see |
Product Details anti-CD11b AntibodyTarget Details CD11b Application Details Handling Images |
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Specificity | The rat monoclonal antibody M1/70 detects CD11b (integrin alphaM subunit), a type I transmembrane protein mainly expressed on monocytes/macrophages, granulocytes and NK-cells, which associates with CD18 to form Mac-1 integrin that plays important role in cell-cell interactions. |
Purification | Protein G purified |
Endotoxin Level | Low Endotoxin |
Immunogen |
B10 mouse spleen cells enriched for T cells. Type of Immunogen: Cells |
Clone | M1-70 |
Isotype | IgG2b |
Plasmids, Primers & others | |
Target Details CD11bProduct Details anti-CD11b Antibody Application Details Handling Images back to top |
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Antigen | |
Alternative Name | ITGAM / CD11b (ITGAM Antibody Abstract) |
Background |
Name/Gene ID: ITGAM Family: Integrin Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain |
Gene ID | 3684 |
UniProt | P11215 |
Pathways | Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation |
Application DetailsProduct Details anti-CD11b Antibody Target Details CD11b Handling Images back to top |
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Application Notes |
Approved: Block, Flo, Func, IHC, IHC-Fr, IP, Neut Usage: Flow Cytometry: Recommended dilution - 1 μg/mL. Functional Application: In vitro blocking of CD11b. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. |
Comment |
Target Species of Antibody: Mouse |
Restrictions | For Research Use only |
HandlingProduct Details anti-CD11b Antibody Target Details CD11b Application Details Images back to top |
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Format | Liquid |
Concentration | Lot specific |
Buffer | Azide-free PBS, pH 7.4, 0.2 micron filter sterilized |
Preservative | Azide free, Sodium azide |
Precaution of Use | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Handling Advice | Avoid freeze/thaw cycles. This low endotoxin solution contains no preservative, handle under aseptic conditions. |
Storage | 4 °C,-20 °C |
Storage Comment |
Store at 2-8°C. For long-term storage aliquot and store at -20°C. Avoid freeze/thaw cycles. This low endotoxin solution contains no preservative handle under aseptic conditions. |