anti-Pig (Porcine) CD11b antibody for Functional Studies

Recommended CD11b Antibody (supplied by: Log in to see )

Antigen
Integrin alpha M (ITGAM) Antibodies
  • CD11b/CD18
  • CR3
  • CR3A
  • Cd11b
  • F730045J24Rik
  • Ly-40
  • MAC1
  • Mac-1
  • Mac-1a
  • CD11B
  • MAC-1
  • MAC1A
  • MO1A
  • SLEB6
  • C3bi
  • integrin subunit alpha M
  • integrin alpha M
  • integrin, alpha M (complement component 3 receptor 3 subunit)
  • integrin alpha-M
  • ITGAM
  • Itgam
  • LOC100351865
Reactivity
Cow (Bovine), Dog (Canine), Cat (Feline), Goat, Mustelid, Pig (Porcine)
772
504
173
105
37
33
32
25
14
12
10
9
9
7
6
4
3
3
2
2
Host
Mouse
546
412
165
17
4
2
Clonality
Monoclonal
Conjugate
This CD11b antibody is un-conjugated
147
127
98
65
19
19
17
16
14
14
14
13
12
11
11
9
9
8
8
7
6
6
5
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Functional Studies (Func), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)
921
272
221
202
174
162
94
92
92
61
26
21
13
13
9
8
5
5
4
3
3
2
1
1
1
1
1
1
1
1
1
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Catalog No. ABIN317369
$ 687.50
Plus shipping costs $45.00

General

Antigen Integrin alpha M (ITGAM) Antibodies
Reactivity Cow (Bovine), Dog (Canine), Cat (Feline), Goat, Mustelid, Pig (Porcine)
(772), (504), (173), (105), (37), (33), (32), (25), (14), (12), (10), (9), (9), (7), (6), (4), (3), (3), (2), (2)
Host Mouse
(546), (412), (165), (17), (4), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD11b antibody is un-conjugated
(147), (127), (98), (65), (19), (19), (17), (16), (14), (14), (14), (13), (12), (11), (11), (9), (9), (8), (8), (7), (6), (6), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Functional Studies (Func), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)
(921), (272), (221), (202), (174), (162), (94), (92), (92), (61), (26), (21), (13), (13), (9), (8), (5), (5), (4), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-CD11b Antibody

Target Details CD11b Application Details Handling References for anti-CD11b antibody (ABIN317369) Images
Specificity This antibody recognises the Canine CD11b cell surface antigen, a member of the alpha integrin family. Canine CD11b is expressed by granulocytes, monocytes and some macrophages.
Characteristics Synonyms: Integrin alpha-M, CR3A, MAC-1, MAC1, CR-3 alpha chain, Cell surface glycoprotein MAC-1subunit alpha, Leukocyte adhesion receptor MO1, Neutrophil adherence receptor, CD11antigen-like family member B
Purification Supernatant
Clone CA16-3E10
Isotype IgG1
Plasmids, Primers & others

Target Details CD11b

Product Details anti-CD11b Antibody Application Details Handling References for anti-CD11b antibody (ABIN317369) Images back to top
Antigen
Alternative Name CD11b (ITGAM Antibody Abstract)
Background CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement coated particles. It is identical to CR3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the RGD peptide in C3b. CD11b is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. The Mac1 CD11b antigen is present on macrophages, granulocytes, natural killer cells, blood monocytes. CD11b is expressed on 8 % spleen cells, 44 % bone marrow cells and less than 1 % of thymocytes and is commonly used as a microglial marker in nervous tissue.Synonyms: CD11 antigen-like family member B, CR-3 alpha chain, CR3A, Cell surface glycoprotein MAC-1 subunit alpha, ITGAM, Integrin alpha-M, Leukocyte adhesion receptor MO1, MAC1, Neutrophil adherence receptor
Gene ID 443217
UniProt A2TJJ2
Pathways Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation

Application Details

Product Details anti-CD11b Antibody Target Details CD11b Handling References for anti-CD11b antibody (ABIN317369) Images back to top
Application Notes Immunohistochemistry on Frozen Sections. Immunoprecipitation. Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-CD11b Antibody Target Details CD11b Application Details References for anti-CD11b antibody (ABIN317369) Images back to top
Format Liquid
Buffer Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Expiry Date 12 months

References for anti-CD11b antibody (ABIN317369)

Product Details anti-CD11b Antibody Target Details CD11b Application Details Handling Images back to top
Background publications

Brodersen, Bijlsma, Gori, Jensen, Chen, Dominguez, Haverson, Moore, Saalmüller, Sachs, Slierendrecht, Stokes, Vainio, Zuckermann, Aasted: "Analysis of the immunological cross reactivities of 213 well characterized monoclonal antibodies with specificities against various leucocyte surface antigens of human and 11 animal species." in: Veterinary immunology and immunopathology, Vol. 64, Issue 1, pp. 1-13, 1998