anti-Human CRADD antibody for Enzyme Immunoassay

Recommended CRADD Antibody (supplied by: Log in to see )

Antigen
CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) Antibodies
  • cradd
  • MGC89035
  • zgc:101717
  • CRADD
  • DKFZp468A2219
  • LOC100226369
  • raidd
  • MGC78788
  • MRT34
  • RAIDD
  • CASP2 and RIPK1 domain containing adaptor with death domain
  • CASP2 and RIPK1 domain containing adaptor with death, gene 1
  • CASP2 and RIPK1 domain containing adaptor with death, gene 2 S homeolog
  • CRADD
  • cradd.1
  • cradd
  • cradd.2.S
  • Cradd
Epitope
C-Term
22
20
12
11
10
9
8
4
4
3
3
1
1
Reactivity
Human
144
18
17
2
1
1
1
1
1
Host
Rabbit
102
40
2
1
Clonality
Polyclonal
Conjugate
This CRADD antibody is un-conjugated
9
9
7
4
4
3
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
135
73
27
17
15
13
9
3
2
1
1
1
Supplier
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Catalog No. ABIN5555153
$ 469.32
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5555152 EIA IF WB Rabbit IgG AA 99-117, Middle Region Log in to see Polyclonal
1 ABIN5540082 EIA WB Mouse IgG1 AA 1-199 Log in to see AT14G8
1 ABIN5540083 EIA WB Mouse IgG1 AA 1-199 Log in to see AT14G8

General

Antigen CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) Antibodies
Epitope C-Term
(22), (20), (12), (11), (10), (9), (8), (4), (4), (3), (3), (1), (1)
Reactivity Human
(144), (18), (17), (2), (1), (1), (1), (1), (1)
Host Rabbit
(102), (40), (2), (1)
Clonality
Polyclonal
Conjugate This CRADD antibody is un-conjugated
(9), (9), (7), (4), (4), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(135), (73), (27), (17), (15), (13), (9), (3), (2), (1), (1), (1)
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Product Details anti-CRADD Antibody

Target Details CRADD Application Details Handling Images
Specificity This antibody detects RAIDD at C-term.
Cross-Reactivity (Details) Species reactivity (tested):Human
Purification Peptide affinity chromatography
Immunogen RAIDD antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of human RAIDD.
Isotype IgG

Target Details CRADD

Product Details anti-CRADD Antibody Application Details Handling Images back to top
Antigen
Alternative Name RAIDD (CRADD Antibody Abstract)
Background Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain (DD)-containing receptors, TNFR1 and Fas. The death signals are transduced by a group of DD-containing adapter molecules. A novel cell death adapter was recently identified by two independent groups and designated RAIDD (RIP-associated ICH-1/CED-3-homologous protein with DD) and CRADD (caspase and RIP adapter with DD)1,RAIDD contains a DD and a CARD (for caspase recruitment domain) which interact with RIP and caspase, respectively, to transduce death signals. RAIDD is constitutively expressed in many tissues and mediates apoptosis caused by Fas and TNFR-1.Synonyms: CRADD, Caspase and RIP adapter with death domain, Death domain-containing protein CRADD, RIP-associated protein with a death domain
Gene ID 8738
UniProt P78560
Research Area Apoptosis/Necrosis, Cancer
Pathways Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-CRADD Antibody Target Details CRADD Handling Images back to top
Application Notes ELISA. Western blot: 1: 500 - 1: 1000, a 22 kDa band should be detected. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-CRADD Antibody Target Details CRADD Application Details Images back to top
Buffer PBS containing 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.