anti-Mouse (Murine) Cytochrome C antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Cytochrome C Antibody (supplied by: Log in to see )

Antigen
Cytochrome C, Somatic (CYCS) Antibodies
  • CYC
  • HCS
  • THC4
  • cyct
  • cyc
  • hcs
  • CYCS
  • cytc
  • CYCSA
  • CG17903
  • Cyt C
  • Cyt c
  • Cyt-c2
  • CytC-2
  • Cytc
  • Cytc-p
  • DC4
  • DMc01
  • Dmel\\CG17903
  • cyt c
  • cyt c-p
  • cyt-c-p
  • cyt-c2
  • cyt.c
  • cytochrome c
  • dc4
  • pDMc01
  • wu:fk52b01
  • zgc:86706
  • cytochrome c, somatic
  • cytochrome c, somatic S homeolog
  • Cytochrome c proximal
  • cytochrome c, somatic b
  • cytochrome c-like
  • cytochrome c
  • CYCS
  • cycs.S
  • cycs
  • Cycs
  • Cyt-c-p
  • cycsb
  • LOC100724240
  • CYC
  • LOC100847700
  • LOC101107954
  • LOC106829744
  • LOC106992390
Epitope
AA 50-89
27
18
15
12
11
8
6
5
5
4
4
3
3
2
2
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
378
314
236
116
95
82
47
38
34
31
26
25
24
20
12
11
8
8
5
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Host
Rabbit
267
165
8
3
Clonality
Polyclonal
Conjugate
This Cytochrome C antibody is un-conjugated
19
11
11
7
6
6
5
5
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Application
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
341
161
131
125
114
73
51
42
40
25
23
12
6
5
4
4
4
4
3
3
3
2
1
1
1
1
1
1
1
1
1
1
Options
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Catalog No. ABIN723590
$ 329.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
33.99479 ABIN3042783 ICC IHC (p) WB Rabbit IgG AA 2-105 Log in to see Polyclonal 20
29.5 ABIN3043697 ICC IHC (fro) IHC (p) WB Rabbit IgG AA 91-105, C-Term Log in to see Polyclonal 19
29.5 ABIN5518904 IHC (p) WB Rabbit IgG AA 2-105 Log in to see Polyclonal 11
23.494791 ABIN5519331 ICC IF IHC (p) ELISA Rabbit IgG Log in to see Polyclonal 0
23.474512 ABIN252468 ICC FACS IF IHC (p) IHC WB Mouse IgG2b kappa Log in to see 7H8-2C12 45
17.494791 ABIN462359 IHC IHC (p) WB Mouse IgG2b Log in to see 7H8-2C12 0
15.974512 ABIN4301949 ICC IF IHC IHC (fro) IHC (p) WB Rabbit IgG Log in to see Polyclonal 1
14.5 ABIN5693008 FACS ICC IHC (fro) IHC (p) WB Mouse IgG1 AA 2-105 Log in to see 15F10 10
13.252602 ABIN1689953 ICC IHC (fro) IHC (p) WB Rabbit Log in to see Polyclonal 0
13 ABIN3030667 ICC IHC (p) WB Rabbit IgG AA 2-105 Log in to see Polyclonal 0
11.494791 ABIN305748 ICC IHC IHC (p) WB Mouse IgG2b AA 1-80 Log in to see 7H8-2C12 0
11.474512 ABIN5948577 ICC IF IHC IHC (p) IP WB Rabbit IgG Log in to see SC59-01 0
10 ABIN1101062 IHC IHC (p) WB Mouse IgG2b, kappa Log in to see 7H8 0
10 ABIN5693541 IHC (p) WB Mouse IgG2b Log in to see 7H8-2C12 0
10 ABIN3030666 ICC IHC (fro) IHC (p) WB Rabbit IgG AA 91-105 Log in to see Polyclonal 0
8.494791 ABIN1106890 IHC (fro) IF IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal 0
8.474512 ABIN5948578 ICC IF IHC IHC (p) IP WB Rabbit IgG Log in to see SC69-08 0
7 ABIN1493494 ICC IHC IHC (fro) IHC (p) WB Rabbit AA 91-105 Log in to see Polyclonal 0
7 ABIN265383 IHC (p) WB Rabbit Log in to see Polyclonal 0
7 ABIN3025122 FACS IF IHC (p) WB Mouse IgG2b, kappa AA 1-80 Log in to see 7H8-2C12 0

General

Antigen Cytochrome C, Somatic (CYCS) Antibodies
Epitope AA 50-89
(27), (18), (15), (12), (11), (8), (6), (5), (5), (4), (4), (3), (3), (2), (2), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(378), (314), (236), (116), (95), (82), (47), (38), (34), (31), (26), (25), (24), (20), (12), (11), (8), (8), (5), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Host Rabbit
(267), (165), (8), (3)
Clonality
Polyclonal
Conjugate This Cytochrome C antibody is un-conjugated
(19), (11), (11), (7), (6), (6), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(341), (161), (131), (125), (114), (73), (51), (42), (40), (25), (23), (12), (6), (5), (4), (4), (4), (4), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 14 references available
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Product Details anti-Cytochrome C Antibody

Target Details Cytochrome C Application Details Handling References for anti-Cytochrome C antibody (ABIN723590) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human Cytochrome C
Isotype IgG
Plasmids, Primers & others

Target Details Cytochrome C

Product Details anti-Cytochrome C Antibody Application Details Handling References for anti-Cytochrome C antibody (ABIN723590) Images back to top
Antigen
Alternative Name Cytochrome C (CYCS Antibody Abstract)
Background

Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

Subcellular location: Mitochondrion

Synonyms: CYC, HCS, THC4, Cytochrome c, CYCS

Gene ID 54205
UniProt P99999
Pathways Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-Cytochrome C Antibody Target Details Cytochrome C Handling References for anti-Cytochrome C antibody (ABIN723590) Images back to top
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-Cytochrome C Antibody Target Details Cytochrome C Application Details References for anti-Cytochrome C antibody (ABIN723590) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-Cytochrome C antibody (ABIN723590)

Product Details anti-Cytochrome C Antibody Target Details Cytochrome C Application Details Handling Images back to top
Product cited in:

Liu, Chen, Du, Wu, Dong, Qu, Fan, Yao: "GluR3B Ab's induced oligodendrocyte precursor cells excitotoxicity via mitochondrial dysfunction." in: Brain research bulletin, Vol. 130, pp. 60-66, 2017 Method employed by authors: Immunofluorescence (fixed cells) (IF/ICC), Immunofluorescence (fixed cells) (IF/ICC) (Sample species: Rat (Rattus)).

Abdel-Hamid, El-Azab, Moustafa: "Macrolide antibiotics differentially influence human HepG2 cytotoxicity and modulate intrinsic/extrinsic apoptotic pathways in rat hepatocellular carcinoma model." in: Naunyn-Schmiedeberg's archives of pharmacology, Vol. 390, Issue 4, pp. 379-395, 2017 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Rat (Rattus)). Further details: Sample: liver

Gu, Chen, Jiang, Zhang: "ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction underlie apoptosis induced by resveratrol and arsenic trioxide in A549 cells." in: Chemico-biological interactions, Vol. 245, pp. 100-9, 2016 Method employed by authors: Western Blotting (WB) (Sample species: Human).

Duan, Li, Li, Xing, Zhang, Li, Zhao, Sun, Gao, Li et al.: "Antioxidant tert-butylhydroquinone ameliorates arsenic-induced intracellular damages and apoptosis through induction of Nrf2-dependent antioxidant responses as well as stabilization of anti-apoptotic ..." in: Free radical biology & medicine, Vol. 94, pp. 74-87, 2016 Method employed by authors: Western Blotting (WB), Western Blotting (WB) (Sample species: Human).

Gu, Chen, Jiang, Zhang: "Resveratrol Synergistically Triggers Apoptotic Cell Death with Arsenic Trioxide via Oxidative Stress in Human Lung Adenocarcinoma A549 Cells." in: Biological trace element research, Vol. 163, Issue 1-2, pp. 112-23, 2015 Method employed by authors: Western Blotting (WB) (Sample species: Human).

Gao, Yu, Yan, Li, Shen, Jia, Guan, Gao, Kan: "Poly (ADP?ribose) polymerase? and cytochrome c?mediated apoptosis induces hepatocyte injury in a rat model of hyperammonia?induced hepatic failure." in: Molecular medicine reports, 2015 Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)). Further details: Sample: Liver

Li, Li, Sun, Ni, Chen, Guo, Chen: "Increased Expression of Mitochondrial Inner-Membrane Protein Mpv17 After Intracerebral Hemorrhage in Adult Rats." in: Neurochemical research, Vol. 40, Issue 8, pp. 1620-30, 2015 Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)). Further details: Sample: Brain

Chen, Gu, Jiang, Zhang: "Nuclear translocation of nuclear factor kappa B is regulated by G protein signaling pathway in arsenite-induced apoptosis in HBE cell line." in: Environmental toxicology, 2015 Method employed by authors: Western Blotting (WB) (Sample species: Human).

Ye, Wu, Li, Li, Zheng, Liu, Ye: "Millimeter Wave Treatment Inhibits Apoptosis of Chondrocytes via Regulation Dynamic Equilibrium of Intracellular Free Ca (2+)." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2015, pp. 464161, 2015 (Sample species: Rat (Rattus)).

Jiang, Ren, Jiang, Wang, Zhang, Yin, Wang, Qi, Wang, Feng: "Guanabenz delays the onset of disease symptoms, extends lifespan, improves motor performance and attenuates motor neuron loss in the SOD1 G93A mouse model of amyotrophic lateral sclerosis." in: Neuroscience, Vol. 277, pp. 132-8, 2014 Method employed by authors: Western Blotting (WB) (Sample species: Mouse (Murine)).

Chen, Jiang, Lai, Liu, Zhang: "Resveratrol protects against arsenic trioxide-induced oxidative damage through maintenance of glutathione homeostasis and inhibition of apoptotic progression." in: Environmental and molecular mutagenesis, 2014 Method employed by authors: Western Blotting (WB) (Sample species: Human).

Fang, Zhang, Qi, Fan, Luo, Liu, Tan: "Evodiamine induces G2/M arrest and apoptosis via mitochondrial and endoplasmic reticulum pathways in H446 and H1688 human small-cell lung cancer cells." in: PLoS ONE, Vol. 9, Issue 12, pp. e115204, 2014 Method employed by authors: Western Blotting (WB) (Sample species: Human).

Liao, Li, Li, Liu: "Organellar proteome analyses of ricin toxin-treated HeLa cells." in: Toxicology and industrial health, 2014 Method employed by authors: Western Blotting (WB) (Sample species: Human).

Wang, Wang, Shan, Song, Dai, Wang, Chi: "Mu-calpain mediates hippocampal neuron death in rats after lithium-pilocarpine-induced status epilepticus." in: Brain research bulletin, Vol. 76, Issue 1-2, pp. 90-6, 2008 Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)). Further details: Sample: brain

Images

Product Details anti-Cytochrome C Antibody Target Details Cytochrome C Application Details Handling References for anti-Cytochrome C antibody (ABIN723590) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Cytochrome C, Somatic (CYCS) (AA 50-89) antibody (ABIN723590) Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-Cytochrome C ...
SDS-PAGE (SDS) image for anti-Cytochrome C, Somatic (CYCS) (AA 50-89) antibody (ABIN723590) L1 mouse brain lysates L2 mouse lung lysates probed with Anti Cytochrome C Polyclonal...
Western Blotting (WB) image for anti-Cytochrome C, Somatic (CYCS) (AA 50-89) antibody (ABIN723590) Mouse heart probed with Anti-Cytochrome C Polyclonal Antibody Unconjugated at 1:5000...
Immunofluorescence (IF) image for anti-Cytochrome C, Somatic (CYCS) (AA 50-89) antibody (ABIN723590) Image kindly submitted by an end-user via Funakoshi. 4% Paraformaldehyde fixed HeLa c...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Cytochrome C, Somatic (CYCS) (AA 50-89) antibody (ABIN723590) Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-Cytochrome C ...
 image for anti-Cytochrome C, Somatic (CYCS) (AA 50-89) antibody (ABIN723590) HepG2 cells probed with Cytochrome C Polyclonal Antibody, unconjugated at 1:100 dilu...