anti-Cow (Bovine) KRT18 antibody for Immunofluorescence

Recommended KRT18 Antibody

Antigen
Keratin 18 (KRT18) Antibodies
  • CK18
  • K18
  • Krt1-18
  • CYK18
  • DreK18
  • cb83
  • dapk1
  • sb:cb83
  • wu:fa13f02
  • wu:fb36b04
  • krt18
  • MGC64569
  • MGC75922
  • KRT18
  • keratin 18
  • keratin 18, type I L homeolog
  • keratin 18, type I
  • keratin, type I cytoskeletal 18
  • K18, simple type I keratin
  • Keratin, type I cytoskeletal 18
  • Krt18
  • KRT18
  • krt18
  • krt18.L
  • LOC700569
  • LOC100136778
  • k1c18
  • LOC100008885
Reactivity
Cow (Bovine), Dog (Canine), Hamster, Human, Mouse (Murine), Pig (Porcine), Rat (Rattus), Sheep (Ovine), Trout
913
216
214
116
86
60
58
45
41
36
32
27
27
27
26
15
11
9
5
4
3
2
1
1
1
1
Host
Mouse
598
344
14
13
5
2
2
Clonality
Monoclonal
Conjugate
This KRT18 antibody is conjugated to FITC
56
41
18
11
11
11
11
11
11
10
9
9
8
8
8
8
8
8
8
8
8
8
8
8
8
8
3
3
3
3
3
2
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
585
380
357
349
264
206
171
103
87
79
45
40
18
14
11
3
1
1
1
Options
Catalog No. ABIN111182
$ 412.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
7 ABIN3026966 FACS IF IHC (p) WB Mouse IgG1, kappa C-04 or Ks18-04 0
7 ABIN3026968 FACS IF IHC (p) WB Mouse IgG1, kappa C-04 or Ks18-04 0
4 ABIN6179188 FACS IF IHC (f) APC Mouse IgG1, kappa C-04 0
4 ABIN6179195 FACS IF IHC (f) PerCP Mouse IgG1, kappa C-04 0
4 ABIN6179196 FACS IF IHC (f) PE Mouse IgG1, kappa C-04 0
4 ABIN6179199 FACS IF IHC (f) Mouse IgG1, kappa C-04 0
1 ABIN6179184 FACS IF IHC (f) CF®488A Mouse IgG1, kappa C-04 0
1 ABIN6179174 FACS IF IHC (f) CF®660R Mouse IgG1, kappa C-04 0
1 ABIN6179180 FACS IF IHC (f) CF®680 Mouse IgG1, kappa C-04 0
1 ABIN6179164 FACS IF IHC (f) CF405M Mouse IgG1, kappa C-04 0
1 ABIN6179166 FACS IF IHC (f) CF®640R Mouse IgG1, kappa C-04 0
1 ABIN6179170 FACS IF IHC (f) CF®647 Mouse IgG1, kappa C-04 0
1 ABIN6179186 FACS IF IHC (f) CF®594 Mouse IgG1, kappa C-04 0
1 ABIN6179182 FACS IF IHC (f) CF®680R Mouse IgG1, kappa C-04 0
1 ABIN6179178 FACS IF IHC (f) CF®770 Mouse IgG1, kappa C-04 0
1 ABIN6179162 FACS IF IHC (f) CF®405S Mouse IgG1, kappa C-04 0
1 ABIN6179172 FACS IF IHC (f) CF®555 Mouse IgG1, kappa C-04 0
1 ABIN6179168 FACS IF IHC (f) CF®543 Mouse IgG1, kappa C-04 0
1 ABIN6179176 FACS IF IHC (f) CF®568 Mouse IgG1, kappa C-04 0
1 ABIN6179197 FACS IF IHC (f) Mouse IgG1, kappa C-04 0

General

Antigen Keratin 18 (KRT18) Antibodies
Reactivity Cow (Bovine), Dog (Canine), Hamster, Human, Mouse (Murine), Pig (Porcine), Rat (Rattus), Sheep (Ovine), Trout
(913), (216), (214), (116), (86), (60), (58), (45), (41), (36), (32), (27), (27), (27), (26), (15), (11), (9), (5), (4), (3), (2), (1), (1), (1), (1)
Host Mouse
(598), (344), (14), (13), (5), (2), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This KRT18 antibody is conjugated to FITC
(56), (41), (18), (11), (11), (11), (11), (11), (11), (10), (9), (9), (8), (8), (8), (8), (8), (8), (8), (8), (8), (8), (8), (8), (8), (8), (3), (3), (3), (3), (3), (2), (1)
Application Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(585), (380), (357), (349), (264), (206), (171), (103), (87), (79), (45), (40), (18), (14), (11), (3), (1), (1), (1)
Pubmed 10 references available
Supplier

Product Details anti-KRT18 Antibody

Target Details KRT18 Application Details Handling References for anti-KRT18 antibody (ABIN111182) Images
Specificity Ks 18.04 represents an excellent marker to discriminate simple epithelia from those of different origin. Tumors Specifically Detected: all adenocarcinoma, mammary carcinoma, urinary bladder carcinoma, undifferentiated carcinoma, cervix carcinoma, hepatocellular carcinoma. Polypeptide Reacting: Mr 45 000 polypeptide (human keratin K18) of all simple type epithelia and basal cells of many squamous, nonepidermal epithelia. Reacts with HeLa and MCF-7 (cell lines tested so far).
Purification Protein A Chromatography
Immunogen Human keratin K18 from a HeLa cytoskeletal preparation
Clone Ks18-04
Isotype IgG1
Plasmids, Primers & others

Target Details KRT18

Product Details anti-KRT18 Antibody Application Details Handling References for anti-KRT18 antibody (ABIN111182) Images back to top
Antigen
Alternative Name Cytokeratin 18 (KRT18 Antibody Abstract)
Background Cytokeratin 18 is an acidic keratin which is found primarily in non squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas but not in squamous cell carcinomas. Cytokeratin 18 exists in combination with Cytokeratin 8, a basic keratin. Hepatocellular carcinomas have been reportedly defined by the use of antibodies that recognize only Cytokeratins 8 and 18.Synonyms: CK18, CYK18, Cell proliferation-inducing gene 46 protein, Cytokeratin-18, K18, KRT18, Keratin 18, Keratin type I cytoskeletal 18, Keratin-18
Gene ID 3875
NCBI Accession NP_000215
UniProt P05783
Pathways Apoptosis, Caspase Cascade in Apoptosis

Application Details

Product Details anti-KRT18 Antibody Target Details KRT18 Handling References for anti-KRT18 antibody (ABIN111182) Images back to top
Application Notes Immunoflourescence. Cytological material. Flow Cytometry: 1/5-1/10. Immunohistochemistry of Frozen Sections. Immunohistochemistry of Paraffin Sections: 1/10. Working dilution: 1/10 for immunohistochemistry. Incubation Time: 1 h at 37 °C.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-KRT18 Antibody Target Details KRT18 Application Details References for anti-KRT18 antibody (ABIN111182) Images back to top
Format Liquid
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-KRT18 antibody (ABIN111182)

Product Details anti-KRT18 Antibody Target Details KRT18 Application Details Handling Images back to top
Product cited in:

Trowe, Airik, Weiss, Farin, Foik, Bettenhausen, Schuster-Gossler, Taketo, Kispert: "Canonical Wnt signaling regulates smooth muscle precursor development in the mouse ureter." in: Development (Cambridge, England), Vol. 139, Issue 17, pp. 3099-108, 2012

Hantel, Lewrick, Schneider, Zwermann, Perren, Reincke, Süss, Beuschlein: "Anti insulin-like growth factor I receptor immunoliposomes: a single formulation combining two anticancer treatments with enhanced therapeutic efficiency." in: The Journal of clinical endocrinology and metabolism, Vol. 95, Issue 2, pp. 943-52, 2010

Sharma, Cantz, Richter, Eckert, Henschler, Wilkens, Jochheim-Richter, Arseniev, Ott: "Human cord blood stem cells generate human cytokeratin 18-negative hepatocyte-like cells in injured mouse liver." in: The American journal of pathology, Vol. 167, Issue 2, pp. 555-64, 2005

Ikenouchi, Matsuda, Furuse, Tsukita: "Regulation of tight junctions during the epithelium-mesenchyme transition: direct repression of the gene expression of claudins/occludin by Snail." in: Journal of cell science, Vol. 116, Issue Pt 10, pp. 1959-67, 2003

Stumptner, Fuchsbichler, Heid, Zatloukal, Denk: "Mallory body--a disease-associated type of sequestosome." in: Hepatology (Baltimore, Md.), Vol. 35, Issue 5, pp. 1053-62, 2002

Bantel, Ruck, Gregor, Schulze-Osthoff: "Detection of elevated caspase activation and early apoptosis in liver diseases." in: European journal of cell biology, Vol. 80, Issue 3, pp. 230-9, 2001

Gomi, Yokoyama, Fujimoto, Ikeda, Katoh, Itoh, Itohara: "Mice devoid of the glial fibrillary acidic protein develop normally and are susceptible to scrapie prions." in: Neuron, Vol. 14, Issue 1, pp. 29-41, 1995

Bártek, Vojt?sek, Stasková, Bártková, Kerekés, Rejthar, Kovarík: "A series of 14 new monoclonal antibodies to keratins: characterization and value in diagnostic histopathology." in: The Journal of pathology, Vol. 164, Issue 3, pp. 215-24, 1991

Lauerová, Kovarik, Bártek, Rejthar, Vojt?sek: "Novel monoclonal antibodies defining epitope of human cytokeratin 18 molecule." in: Hybridoma, Vol. 7, Issue 5, pp. 495-504, 1989

Moll, Franke, Schiller, Geiger, Krepler: "The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells." in: Cell, Vol. 31, Issue 1, pp. 11-24, 1983