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General |
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Antigen | Keratin 18 (KRT18) Antibodies |
Epitope | C-Term Alternatives |
Reactivity | Human, Mouse (Murine) Alternatives |
Host | Rabbit Alternatives |
Clonality | |
Conjugate | This KRT18 antibody is un-conjugated Alternatives |
Application |
Enzyme Immunoassay (EIA), Western Blotting (WB)
Alternatives
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2 references available |
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Product Details anti-KRT18 AntibodyTarget Details KRT18 Application Details Handling References for anti-KRT18 antibody (ABIN452897) Images |
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Specificity | This antibody detects Cytokeratin-18 (KRT18) at C-term. |
Cross-Reactivity (Details) | Species reactivity (tested):Human, Mouse |
Purification | Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS |
Immunogen | KLH conjugated synthetic peptide selected from the C-terminal region of human CYK18 |
Target Details KRT18Product Details anti-KRT18 Antibody Application Details Handling References for anti-KRT18 antibody (ABIN452897) Images back to top |
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Antigen | |
Alternative Name | Cytokeratin 18 (KRT18 Antibody Abstract) |
Background | KRT18 is the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament family. They are expressed in single layer epithelial tissues of the body. Mutations in its gene have been linked to cryptogenic cirrhosis.Synonyms: CK18, CYK18, Cell proliferation-inducing gene 46 protein, Cytokeratin-18, K18, KRT18, Keratin 18, Keratin type I cytoskeletal 18, Keratin-18 |
Molecular Weight | 48058 Da |
Gene ID | 3875 |
NCBI Accession | NP_000215 |
UniProt | P05783 |
Pathways | Apoptosis, Caspase Cascade in Apoptosis |
Application DetailsProduct Details anti-KRT18 Antibody Target Details KRT18 Handling References for anti-KRT18 antibody (ABIN452897) Images back to top |
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Application Notes |
Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. |
Restrictions | For Research Use only |
HandlingProduct Details anti-KRT18 Antibody Target Details KRT18 Application Details References for anti-KRT18 antibody (ABIN452897) Images back to top |
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Format | Liquid |
Concentration | 0.25 mg/mL |
Buffer | PBS with 0.09 % (W/V) sodium azide |
Preservative | Sodium azide |
Precaution of Use | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Handling Advice | Avoid repeated freezing and thawing. |
Storage | 4 °C/-20 °C |
Storage Comment | Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. |
References for anti-KRT18 antibody (ABIN452897)Product Details anti-KRT18 Antibody Target Details KRT18 Application Details Handling Images back to top |
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Background publications |
Zhang, Helfand, Jang, Zhu, Chen, Yang, Kozlowski, Smith, Kundu, Yang, Raji, Javonovic, Pins, Lindholm, Guo, Catalona, Lee: "Nuclear factor-kappaB-mediated transforming growth factor-beta-induced expression of vimentin is an independent predictor of biochemical recurrence after radical prostatectomy." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 10, pp. 3557-67, 2009 Kruse, Eigelshoven, Kaiser, Ruzicka, Neumann: "Cytokeratin 18 expression in immature Sertoli cells: co-localization with interstitial lymphocytic infiltrates." in: Folia histochemica et cytobiologica / Polish Academy of Sciences, Polish Histochemical and Cytochemical Society, Vol. 47, Issue 1, pp. 127-30, 2009 |
ImagesProduct Details anti-KRT18 Antibody Target Details KRT18 Application Details Handling References for anti-KRT18 antibody (ABIN452897) back to top |
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Supplier Images |