anti-Human Lamin A/C antibody for Immunofluorescence

Recommended Lamin A/C Antibody (supplied by: Log in to see )

Antigen
Lamin A/C (LMNA) Antibodies
  • CDCD1
  • CDDC
  • CMD1A
  • CMT2B1
  • EMD2
  • FPL
  • FPLD
  • FPLD2
  • HGPS
  • IDC
  • LDP1
  • LFP
  • LGMD1B
  • LMN1
  • LMNC
  • LMNL1
  • PRO1
  • Dhe
  • 2459
  • 74/76
  • CG6944
  • D5
  • DM[[O]]
  • Dm
  • Dm(0)
  • Dm0
  • Dm1
  • Dm2
  • DmLamin
  • DmO
  • Dm[[0]]
  • Dm[[1]]
  • Dm[[2]]
  • Dm[[mit]]
  • Dm[[o]]
  • Dmel\\CG6944
  • Dmo
  • LAM
  • Lam Dm[[0]]
  • Lam(Dm0)
  • LamDm[[0]]
  • LamDm[[o]]
  • Lam[[Dm0]]
  • Lamin Dm[[0]]
  • jf27
  • l(2)04643
  • l(2)25Ec
  • l(2)gdh-7
  • l(2)gdh7
  • l(2)jf27
  • lam
  • lamDm0
  • lamDm[[0]]
  • lamin
  • lamin Dm0
  • lamin Dm[[0]]
  • misg
  • nlam
  • cb948
  • fk66d12
  • wu:fk66d12
  • lmna-A
  • fpl
  • idc
  • lfp
  • cddc
  • emd2
  • fpld
  • hgps
  • ldp1
  • lmn1
  • lmnc
  • pro1
  • cdcd1
  • cmd1a
  • cmt2b1
  • lgmd1b
  • Lamin-A
  • lamin-L(III)-like
  • lamin A/C
  • lamin A
  • Lamin
  • lamin A/C L homeolog
  • lamin-L(III)-like
  • LMNA
  • Lmna
  • Lam
  • lmna
  • lmna.L
  • LMINA
Epitope
Center
37
25
24
20
20
18
17
12
11
11
9
9
8
7
7
6
4
4
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
443
270
236
99
53
49
25
22
17
10
10
9
5
5
4
4
3
3
2
2
2
1
1
1
1
1
Host
Rabbit
237
211
5
3
Clonality
Polyclonal
Conjugate
This Lamin A/C antibody is un-conjugated
13
12
10
7
7
6
6
6
6
6
6
6
5
5
5
5
4
4
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
406
206
194
155
120
111
75
72
52
17
15
11
2
2
1
1
1
Options
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Catalog No. ABIN2854942
$ 358.60
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
11.599175 ABIN261550 ICC IHC (fro) IF IHC WB Mouse IgG2b Log in to see mab636 1
11.599175 ABIN4330010 ICC IF IHC IHC (p) IP WB Rabbit IgG Center Log in to see Polyclonal 0
11.599175 ABIN2854943 ICC IF IP IHC (p) WB Rabbit IgG Center Log in to see Polyclonal 0
11.599175 ABIN2706460 IC IF IP IHC WB Rabbit pSer392 Log in to see Polyclonal 0
11.599175 ABIN2706457 IC IF IP IHC WB Rabbit Center Log in to see Polyclonal 0
11.599175 ABIN2706458 IC IF IHC WB Rabbit Center Log in to see Polyclonal 0
11.599175 ABIN1531335 IF IHC ELISA WB Rabbit IgG AA 361-410, pSer392 Log in to see Polyclonal 0
11.599175 ABIN1532355 IF IHC ELISA WB Rabbit IgG AA 361-410 Log in to see Polyclonal 0
11.599175 ABIN303591 ICC FACS IHC (fro) IF IHC (p) IP WB Mouse IgG1 AA 464-572 Log in to see JOL2 8
11.599175 ABIN4329984 ICC IF IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
11.599175 ABIN5550472 ICC IF IHC (p) WB Mouse IgG1 kappa AA 422-664, C-Term Log in to see WL4G10 0
11.599175 ABIN4330022 ICC IF WB Mouse IgG1 Log in to see 4C4 0
11.599175 ABIN1873552 IF IHC WB Rabbit IgG Log in to see Polyclonal 0
11.599175 ABIN2668844 ICC IF WB Mouse IgG AA 430-545 Log in to see 3A6-4C11 3
11.599175 ABIN4330008 FACS ICC IF WB Rabbit Log in to see Polyclonal 4
11.599175 ABIN4330024 ICC IF WB Chicken Log in to see Polyclonal 0
11.599175 ABIN5963695 IF IHC WB Rabbit IgG Log in to see Polyclonal 0
11.599175 ABIN4329985 CyTOF FACS ICC IF IHC IHC (fro) IHC (p) WB Mouse IgG3 AA 598-611 Log in to see 133A2 0
11.599175 ABIN108630 ICC IF WB Mouse IgG1 AA 464-572 Log in to see JoL3 2
11.599175 ABIN4330011 ICC IF IHC IHC (p) IP WB Rabbit IgG Center Log in to see Polyclonal 0

General

Antigen Lamin A/C (LMNA) Antibodies
Epitope Center
(37), (25), (24), (20), (20), (18), (17), (12), (11), (11), (9), (9), (8), (7), (7), (6), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(443), (270), (236), (99), (53), (49), (25), (22), (17), (10), (10), (9), (5), (5), (4), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Host Rabbit
(237), (211), (5), (3)
Clonality
Polyclonal
Conjugate This Lamin A/C antibody is un-conjugated
(13), (12), (10), (7), (7), (6), (6), (6), (6), (6), (6), (6), (5), (5), (5), (5), (4), (4), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(406), (206), (194), (155), (120), (111), (75), (72), (52), (17), (15), (11), (2), (2), (1), (1), (1)
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Product Details anti-Lamin A/C Antibody

Target Details Lamin A/C Application Details Handling Images
Characteristics Rabbit Polyclonal antibody to Lamin A + C
Lamin A + C antibody
Purification Purified by antigen-affinity chromatography.
Immunogen Recombinant protein encompassing a sequence within the center region of human Lamin A/C. The exact sequence is proprietary.
Isotype IgG
Plasmids, Primers & others

Target Details Lamin A/C

Product Details anti-Lamin A/C Antibody Application Details Handling Images back to top
Antigen
Alternative Name Lamin A + C (LMNA Antibody Abstract)
Background The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Through alternate splicing, this gene encodes three type A lamin isoforms. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.

Cellular Localization: Nucleus
Molecular Weight 74 kDa
Gene ID 4000
Pathways Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus

Application Details

Product Details anti-Lamin A/C Antibody Target Details Lamin A/C Handling Images back to top
Application Notes Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Immunoprecipitation 1:66-1:500* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Immunoprecipitation1:66-1:500* Western blot1:500-1:3000*
Comment

Positive Control: HeLa nucleus , C2C12 , NIH-3T3

Restrictions For Research Use only

Handling

Product Details anti-Lamin A/C Antibody Target Details Lamin A/C Application Details Images back to top
Format Liquid
Concentration 0.27 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Images

Product Details anti-Lamin A/C Antibody Target Details Lamin A/C Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Lamin A/C (LMNA) (Center) antibody (ABIN2854942) IHC-P Image Lamin A + C antibody detects Lamin A + C protein at nuclear envelope on m...
Immunohistochemistry (IHC) image for anti-Lamin A/C (LMNA) (Center) antibody (ABIN2854942) IHC-P Image Lamin A + C antibody detects Lamin A + C protein at nuclear envelope on m...
Western Blotting (WB) image for anti-Lamin A/C (LMNA) (Center) antibody (ABIN2854942) WB Image Whole cell extract (30 μg) was separated by 7.5% SDS-PAGE, and the membrane ...
Immunofluorescence (IF) image for anti-Lamin A/C (LMNA) (Center) antibody (ABIN2854942) ICC/IF Image Confocal immunofluorescence analysis (Olympus FV10i) of methanol-fixed H...
Western Blotting (WB) image for anti-Lamin A/C (LMNA) (Center) antibody (ABIN2854942) WB Image Lamin A + C antibody detects Lamin A + C protein by Western blot analysis. A...
Immunoprecipitation (IP) image for anti-Lamin A/C (LMNA) (Center) antibody (ABIN2854942) IP Image Immunoprecipitation of Lamin A + C protein from HeLa whole cell extracts usi...
Immunohistochemistry (IHC) image for anti-Lamin A/C (LMNA) (Center) antibody (ABIN2854942) IHC-P Image Lamin A + C antibody detects Lamin A + C protein at nuclear envelope on m...
Immunohistochemistry (IHC) image for anti-Lamin A/C (LMNA) (Center) antibody (ABIN2854942) IHC-P Image Lamin A + C antibody detects Lamin A + C protein at membrane on U87 xenog...
Western Blotting (WB) image for anti-Lamin A/C (LMNA) (Center) antibody (ABIN2854942) WB Image Lamin A + C antibody detects Lamin A + C protein by Western blot analysis. A...
Immunohistochemistry (IHC) image for anti-Lamin A/C (LMNA) (Center) antibody (ABIN2854942) IHC-P Image Lamin A + C antibody detects Lamin A + C protein at nuclear envelope on h...