anti-Human Lamin A/C antibody for Immunoprecipitation

Recommended Lamin A/C Antibody (supplied by: Log in to see )

Antigen
Lamin A/C (LMNA) Antibodies
  • CDCD1
  • CDDC
  • CMD1A
  • CMT2B1
  • EMD2
  • FPL
  • FPLD
  • FPLD2
  • HGPS
  • IDC
  • LDP1
  • LFP
  • LGMD1B
  • LMN1
  • LMNC
  • LMNL1
  • PRO1
  • Dhe
  • 2459
  • 74/76
  • CG6944
  • D5
  • DM[[O]]
  • Dm
  • Dm(0)
  • Dm0
  • Dm1
  • Dm2
  • DmLamin
  • DmO
  • Dm[[0]]
  • Dm[[1]]
  • Dm[[2]]
  • Dm[[mit]]
  • Dm[[o]]
  • Dmel\\CG6944
  • Dmo
  • LAM
  • Lam Dm[[0]]
  • Lam(Dm0)
  • LamDm[[0]]
  • LamDm[[o]]
  • Lam[[Dm0]]
  • Lamin Dm[[0]]
  • jf27
  • l(2)04643
  • l(2)25Ec
  • l(2)gdh-7
  • l(2)gdh7
  • l(2)jf27
  • lam
  • lamDm0
  • lamDm[[0]]
  • lamin
  • lamin Dm0
  • lamin Dm[[0]]
  • misg
  • nlam
  • cb948
  • fk66d12
  • wu:fk66d12
  • lmna-A
  • fpl
  • idc
  • lfp
  • cddc
  • emd2
  • fpld
  • hgps
  • ldp1
  • lmn1
  • lmnc
  • pro1
  • cdcd1
  • cmd1a
  • cmt2b1
  • lgmd1b
  • Lamin-A
  • lamin-L(III)-like
  • lamin A/C
  • lamin A
  • Lamin
  • lamin A/C L homeolog
  • lamin-L(III)-like
  • LMNA
  • Lmna
  • Lam
  • lmna
  • lmna.L
  • LMINA
Epitope
Center
35
27
24
20
20
18
17
11
11
10
9
9
8
7
7
6
4
4
4
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
445
271
236
104
54
51
24
21
15
10
8
7
5
4
3
3
3
2
1
1
1
Host
Rabbit
231
221
5
1
Clonality
Polyclonal
Conjugate
This Lamin A/C antibody is un-conjugated
13
12
10
7
7
7
7
6
6
6
6
6
6
6
5
5
4
4
4
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
408
210
199
163
118
113
78
74
55
17
14
11
2
2
1
1
Options
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Catalog No. ABIN2854942
$ 358.60
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
23.915068 ABIN2854943 ICC IF IP IHC (p) WB Rabbit IgG Center Log in to see Polyclonal 0
23.915068 ABIN4330011 ICC IF IHC IHC (p) IP WB Rabbit IgG Center Log in to see Polyclonal 0
23.915068 ABIN4330010 ICC IF IHC IHC (p) IP WB Rabbit IgG Center Log in to see Polyclonal 0
23.915068 ABIN517538 IP WB Rabbit AA 1-664, full length Log in to see Polyclonal 0
1 ABIN2706460 IC IF IP IHC WB Rabbit pSer392 Log in to see Polyclonal 0
1 ABIN2706457 IC IF IP IHC WB Rabbit Center Log in to see Polyclonal 0
1 ABIN4330049 ELISA ICC IF IP WB Mouse IgG1 kappa Log in to see 12A-2F5 1
1 ABIN4330067 ELISA ICC IF IP WB Mouse IgG1 kappa Log in to see 5H8-B4 1
1 ABIN303591 ICC FACS IHC (fro) IF IHC (p) IP WB Mouse IgG1 AA 464-572 Log in to see JOL2 8
1 ABIN108550 FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG3 kappa AA 598-611 Log in to see 133A2 2
1 ABIN341144 FACS IHC IHC (p) IP WB Mouse IgG1 Log in to see JOL2 0
1 ABIN364367 FACS IHC IHC (p) IP WB Mouse IgG1 AA 464-572 Log in to see JOL2 0
1 ABIN303589 IHC (fro) IF IP WB Mouse IgG AA 572-646 Log in to see JOL4 2
1 ABIN341143 IF IHC IHC (fro) IP WB Mouse IgG AA 572-646 Log in to see JOL4 0
1 ABIN1042615 IHC (fro) IF IP WB Mouse IgG AA 572-646 Log in to see JOL4 1
1 ABIN2668842 ICC IF IP WB Mouse IgG1 C-Term, Mature Log in to see 4A4 1
1 ABIN567991 IF IP WB Mouse IgG2a Log in to see EM-11 1
1 ABIN1042618 ICC IF IP WB Mouse IgG1 Arg478Trp-Mutant Log in to see 12A-2F5 1
1 ABIN1042617 ICC IF IP WB Mouse IgG1 Arg478Trp-Mutant Log in to see 5H8-B4 1
1 ABIN1493017 IP Magnetic Particles Rabbit C-Term Log in to see Polyclonal 0

General

Antigen Lamin A/C (LMNA) Antibodies
Epitope Center
(35), (27), (24), (20), (20), (18), (17), (11), (11), (10), (9), (9), (8), (7), (7), (6), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(445), (271), (236), (104), (54), (51), (24), (21), (15), (10), (8), (7), (5), (4), (3), (3), (3), (2), (1), (1), (1)
Host Rabbit
(231), (221), (5), (1)
Clonality
Polyclonal
Conjugate This Lamin A/C antibody is un-conjugated
(13), (12), (10), (7), (7), (7), (7), (6), (6), (6), (6), (6), (6), (6), (5), (5), (4), (4), (4), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(408), (210), (199), (163), (118), (113), (78), (74), (55), (17), (14), (11), (2), (2), (1), (1)
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Product Details anti-Lamin A/C Antibody

Target Details Lamin A/C Application Details Handling Images
Characteristics Rabbit Polyclonal antibody to Lamin A + C
Lamin A + C antibody
Purification Purified by antigen-affinity chromatography.
Immunogen Recombinant protein encompassing a sequence within the center region of human Lamin A/C. The exact sequence is proprietary.
Isotype IgG
Plasmids, Primers & others

Target Details Lamin A/C

Product Details anti-Lamin A/C Antibody Application Details Handling Images back to top
Antigen
Alternative Name Lamin A + C (LMNA Antibody Abstract)
Background The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Through alternate splicing, this gene encodes three type A lamin isoforms. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.

Cellular Localization: Nucleus
Molecular Weight 74 kDa
Gene ID 4000
Pathways Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus

Application Details

Product Details anti-Lamin A/C Antibody Target Details Lamin A/C Handling Images back to top
Application Notes Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Immunoprecipitation 1:66-1:500* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Immunoprecipitation1:66-1:500* Western blot1:500-1:3000*
Comment

Positive Control: HeLa nucleus , C2C12 , NIH-3T3

Restrictions For Research Use only

Handling

Product Details anti-Lamin A/C Antibody Target Details Lamin A/C Application Details Images back to top
Format Liquid
Concentration 0.27 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Images

Product Details anti-Lamin A/C Antibody Target Details Lamin A/C Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Lamin A/C (LMNA) (Center) antibody (ABIN2854942) IHC-P Image Lamin A + C antibody detects Lamin A + C protein at nuclear envelope on m...
Immunohistochemistry (IHC) image for anti-Lamin A/C (LMNA) (Center) antibody (ABIN2854942) IHC-P Image Lamin A + C antibody detects Lamin A + C protein at nuclear envelope on m...
Western Blotting (WB) image for anti-Lamin A/C (LMNA) (Center) antibody (ABIN2854942) WB Image Whole cell extract (30 μg) was separated by 7.5% SDS-PAGE, and the membrane ...
Immunofluorescence (IF) image for anti-Lamin A/C (LMNA) (Center) antibody (ABIN2854942) ICC/IF Image Confocal immunofluorescence analysis (Olympus FV10i) of methanol-fixed H...
Western Blotting (WB) image for anti-Lamin A/C (LMNA) (Center) antibody (ABIN2854942) WB Image Lamin A + C antibody detects Lamin A + C protein by Western blot analysis. A...
Immunoprecipitation (IP) image for anti-Lamin A/C (LMNA) (Center) antibody (ABIN2854942) IP Image Immunoprecipitation of Lamin A + C protein from HeLa whole cell extracts usi...
Immunohistochemistry (IHC) image for anti-Lamin A/C (LMNA) (Center) antibody (ABIN2854942) IHC-P Image Lamin A + C antibody detects Lamin A + C protein at nuclear envelope on m...
Immunohistochemistry (IHC) image for anti-Lamin A/C (LMNA) (Center) antibody (ABIN2854942) IHC-P Image Lamin A + C antibody detects Lamin A + C protein at membrane on U87 xenog...
Western Blotting (WB) image for anti-Lamin A/C (LMNA) (Center) antibody (ABIN2854942) WB Image Lamin A + C antibody detects Lamin A + C protein by Western blot analysis. A...
Immunohistochemistry (IHC) image for anti-Lamin A/C (LMNA) (Center) antibody (ABIN2854942) IHC-P Image Lamin A + C antibody detects Lamin A + C protein at nuclear envelope on h...