anti-Human Lamin A/C antibody for Western Blotting

Recommended Lamin A/C Antibody (supplied by: Log in to see )

Antigen
Lamin A/C (LMNA) Antibodies
  • CDCD1
  • CDDC
  • CMD1A
  • CMT2B1
  • EMD2
  • FPL
  • FPLD
  • FPLD2
  • HGPS
  • IDC
  • LDP1
  • LFP
  • LGMD1B
  • LMN1
  • LMNC
  • LMNL1
  • PRO1
  • Dhe
  • 2459
  • 74/76
  • CG6944
  • D5
  • DM[[O]]
  • Dm
  • Dm(0)
  • Dm0
  • Dm1
  • Dm2
  • DmLamin
  • DmO
  • Dm[[0]]
  • Dm[[1]]
  • Dm[[2]]
  • Dm[[mit]]
  • Dm[[o]]
  • Dmel\\CG6944
  • Dmo
  • LAM
  • Lam Dm[[0]]
  • Lam(Dm0)
  • LamDm[[0]]
  • LamDm[[o]]
  • Lam[[Dm0]]
  • Lamin Dm[[0]]
  • jf27
  • l(2)04643
  • l(2)25Ec
  • l(2)gdh-7
  • l(2)gdh7
  • l(2)jf27
  • lam
  • lamDm0
  • lamDm[[0]]
  • lamin
  • lamin Dm0
  • lamin Dm[[0]]
  • misg
  • nlam
  • cb948
  • fk66d12
  • wu:fk66d12
  • lmna-A
  • fpl
  • idc
  • lfp
  • cddc
  • emd2
  • fpld
  • hgps
  • ldp1
  • lmn1
  • lmnc
  • pro1
  • cdcd1
  • cmd1a
  • cmt2b1
  • lgmd1b
  • Lamin-A
  • lamin-L(III)-like
  • lamin A/C
  • lamin A
  • Lamin
  • lamin A/C L homeolog
  • lamin-L(III)-like
  • LMNA
  • Lmna
  • Lam
  • lmna
  • lmna.L
  • LMINA
Epitope
AA 430-545
33
26
23
22
18
16
15
14
12
9
9
8
8
7
6
4
4
4
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Hamster, Human, Monkey, Mouse (Murine), Rat (Rattus)
415
255
222
102
53
51
21
19
14
10
8
7
5
5
3
3
2
1
1
1
Host
Mouse
209
205
5
1
Clonality
Monoclonal
Conjugate
This Lamin A/C antibody is un-conjugated
11
11
9
7
7
6
6
6
6
6
6
6
6
6
5
5
4
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
382
192
156
155
109
103
72
66
49
14
11
9
2
2
1
1
Options
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Catalog No. ABIN2668844
$ 495.83
Plus shipping costs $45.00 and $23.00 dry ice
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.2307212 ABIN3043695 ICC IHC (p) WB Rabbit IgG AA 455-469, C-Term Log in to see Polyclonal 2
3.2307212 ABIN3043295 ICC IHC (p) WB Rabbit IgG AA 481-646 Log in to see Polyclonal 2
3.2307212 ABIN2854942 ICC IF IP IHC (p) WB Rabbit IgG Center Log in to see Polyclonal 0
3.2307212 ABIN261550 ICC IHC (fro) IF IHC WB Mouse IgG2b Log in to see mab636 1
3.2307212 ABIN3020785 IHC WB Rabbit IgG Log in to see Polyclonal 0
3.2307212 ABIN2856820 IHC (p) WB Rabbit IgG Center Log in to see Polyclonal 0
3.2307212 ABIN2854943 ICC IF IP IHC (p) WB Rabbit IgG Center Log in to see Polyclonal 0
3.2307212 ABIN2706457 IC IF IP IHC WB Rabbit Center Log in to see Polyclonal 0
3.2307212 ABIN2706459 IHC WB Rabbit Center Log in to see Polyclonal 0
3.2307212 ABIN2706458 IC IF IHC WB Rabbit Center Log in to see Polyclonal 0
3.2307212 ABIN2706460 IC IF IP IHC WB Rabbit pSer392 Log in to see Polyclonal 0
3.2307212 ABIN1532183 ELISA WB Rabbit IgG AA 2-51, pSer22 Log in to see Polyclonal 1
3.2307212 ABIN1533204 ELISA WB Rabbit IgG AA 2-51 Log in to see Polyclonal 1
3.2307212 ABIN4330049 ELISA ICC IF IP WB Mouse IgG1 kappa Log in to see 12A-2F5 1
3.2307212 ABIN223025 IHC WB Rabbit IgG Log in to see Polyclonal 0
3.2307212 ABIN1536093 IHC ELISA WB Rabbit IgG AA 212-261, Cleaved-Asp230 Log in to see Polyclonal 0
3.2307212 ABIN1531335 IF IHC ELISA WB Rabbit IgG AA 361-410, pSer392 Log in to see Polyclonal 0
3.2307212 ABIN1536092 IHC ELISA WB Rabbit IgG AA 181-230, Cleaved-Asp230 Log in to see Polyclonal 0
3.2307212 ABIN1532355 IF IHC ELISA WB Rabbit IgG AA 361-410 Log in to see Polyclonal 0
3.2307212 ABIN4330067 ELISA ICC IF IP WB Mouse IgG1 kappa Log in to see 5H8-B4 1

General

Antigen Lamin A/C (LMNA) Antibodies
Epitope AA 430-545
(33), (26), (23), (22), (18), (16), (15), (14), (12), (9), (9), (8), (8), (7), (6), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Hamster, Human, Monkey, Mouse (Murine), Rat (Rattus)
(415), (255), (222), (102), (53), (51), (21), (19), (14), (10), (8), (7), (5), (5), (3), (3), (2), (1), (1), (1)
Host Mouse
(209), (205), (5), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Lamin A/C antibody is un-conjugated
(11), (11), (9), (7), (7), (6), (6), (6), (6), (6), (6), (6), (6), (6), (5), (5), (4), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
(382), (192), (156), (155), (109), (103), (72), (66), (49), (14), (11), (9), (2), (2), (1), (1)
Pubmed 3 references available
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Product Details anti-Lamin A/C Antibody

Target Details Lamin A/C Application Details Handling References for anti-Lamin A/C antibody (ABIN2668844) Images
Purification Culture Supernatant
Immunogen This Lamin A/C antibody was raised against a recombinant protein corresponding to amino acids 430-545 of human Lamin A.
Clone 3A6-4C11
Isotype IgG

Target Details Lamin A/C

Product Details anti-Lamin A/C Antibody Application Details Handling References for anti-Lamin A/C antibody (ABIN2668844) Images back to top
Antigen
Alternative Name Lamin A/C (LMNA Antibody Abstract)
Background Nuclear lamins are intermediate filament proteins that are the major structural component of the nuclear lamina on the inner surface of the nuclear envelope. Lamins A and Lamins C are splice variants of the Lamin A gene. Lamin A/C (CDCD1, LMN1, EMD2) expression is a hallmark of embryonic stem cell differentiation. In addition to adding structural integrity to the nucleus, lamins contribute to the makeup of the nuclear matrix. Lamins also help organize interphase chromatin through interactions with several chromatin proteins, including histones and Lap2, such that alteration in lamin organization results in disruption of DNA replication, transcription and RNA processing.
Molecular Weight 75 kDa
Gene ID 4000
Pathways Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus

Application Details

Product Details anti-Lamin A/C Antibody Target Details Lamin A/C Handling References for anti-Lamin A/C antibody (ABIN2668844) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-Lamin A/C Antibody Target Details Lamin A/C Application Details References for anti-Lamin A/C antibody (ABIN2668844) Images back to top
Concentration 1 μg/μL
Buffer Cell culture supernatant containing mouse IgG, 30 % glycerol, 0.035 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Storage -20 °C
Storage Comment Antibodies in solution can be stored at -20 °C for 2 years.
Expiry Date 6 months

References for anti-Lamin A/C antibody (ABIN2668844)

Product Details anti-Lamin A/C Antibody Target Details Lamin A/C Application Details Handling Images back to top
Product cited in:

Gesson, Rescheneder, Skoruppa, von Haeseler, Dechat, Foisner: "A-type lamins bind both hetero- and euchromatin, the latter being regulated by lamina-associated polypeptide 2 alpha." in: Genome research, Vol. 26, Issue 4, pp. 462-73, 2016

Kim, Zheng: "Generation and characterization of a conditional deletion allele for Lmna in mice." in: Biochemical and biophysical research communications, Vol. 440, Issue 1, pp. 8-13, 2013

Eckersley-Maslin, Bergmann, Lazar, Spector: "Lamin A/C is expressed in pluripotent mouse embryonic stem cells." in: Nucleus (Austin, Tex.), Vol. 4, Issue 1, pp. 53-60, 2013

Images

Product Details anti-Lamin A/C Antibody Target Details Lamin A/C Application Details Handling References for anti-Lamin A/C antibody (ABIN2668844) back to top
Supplier Images
Immunofluorescence (IF) image for anti-Lamin A/C (LMNA) (AA 430-545) antibody (ABIN2668844) Lamin A/C mAb (Clone 3A6-4C11) tested by immunofluorescence. Staining of HeLa cells w...
Western Blotting (WB) image for anti-Lamin A/C (LMNA) (AA 430-545) antibody (ABIN2668844) Lamin A/C mAb (Clone 3A6-4C11) tested by Western blot. Whole-cell extract (20 µg) of ...