anti-Mouse (Murine) Lamin A/C antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Lamin A/C Antibody (supplied by: Log in to see )

Antigen
Lamin A/C (LMNA) Antibodies
  • CDCD1
  • CDDC
  • CMD1A
  • CMT2B1
  • EMD2
  • FPL
  • FPLD
  • FPLD2
  • HGPS
  • IDC
  • LDP1
  • LFP
  • LGMD1B
  • LMN1
  • LMNC
  • LMNL1
  • PRO1
  • Dhe
  • 2459
  • 74/76
  • CG6944
  • D5
  • DM[[O]]
  • Dm
  • Dm(0)
  • Dm0
  • Dm1
  • Dm2
  • DmLamin
  • DmO
  • Dm[[0]]
  • Dm[[1]]
  • Dm[[2]]
  • Dm[[mit]]
  • Dm[[o]]
  • Dmel\\CG6944
  • Dmo
  • LAM
  • Lam Dm[[0]]
  • Lam(Dm0)
  • LamDm[[0]]
  • LamDm[[o]]
  • Lam[[Dm0]]
  • Lamin Dm[[0]]
  • jf27
  • l(2)04643
  • l(2)25Ec
  • l(2)gdh-7
  • l(2)gdh7
  • l(2)jf27
  • lam
  • lamDm0
  • lamDm[[0]]
  • lamin
  • lamin Dm0
  • lamin Dm[[0]]
  • misg
  • nlam
  • cb948
  • fk66d12
  • wu:fk66d12
  • lmna-A
  • fpl
  • idc
  • lfp
  • cddc
  • emd2
  • fpld
  • hgps
  • ldp1
  • lmn1
  • lmnc
  • pro1
  • cdcd1
  • cmd1a
  • cmt2b1
  • lgmd1b
  • Lamin-A
  • lamin-L(III)-like
  • lamin A/C
  • lamin A
  • Lamin
  • lamin A/C L homeolog
  • lamin-L(III)-like
  • LMNA
  • Lmna
  • Lam
  • lmna
  • lmna.L
  • LMINA
Epitope
Center
37
25
25
20
20
18
17
12
11
11
9
9
8
7
7
6
4
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
449
272
236
99
53
49
25
22
17
10
10
9
5
5
4
4
3
3
2
2
2
1
1
1
1
1
Host
Rabbit
239
218
5
3
Clonality
Polyclonal
Conjugate
This Lamin A/C antibody is un-conjugated
13
12
10
7
7
6
6
6
6
6
6
6
5
5
5
5
4
4
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
415
206
197
154
121
111
77
72
53
17
15
11
2
2
1
1
1
1
Options
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Catalog No. ABIN2854942
$ 466.18
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
30.811333 ABIN2856820 IHC (p) WB Rabbit IgG Center Log in to see Polyclonal 0
30.811333 ABIN2854943 ICC IF IP IHC (p) WB Rabbit IgG Center Log in to see Polyclonal 0
20.5 ABIN3043295 ICC IHC (p) WB Rabbit IgG AA 481-646 Log in to see Polyclonal 3
17.5 ABIN3043695 ICC IHC (p) WB Rabbit IgG AA 455-469, C-Term Log in to see Polyclonal 3
13 ABIN3031583 ICC IHC (p) WB Rabbit IgG AA 481-646 Log in to see Polyclonal 0
13 ABIN1108015 EIA IHC (p) WB Mouse IgG1 Log in to see 4-00E-007 0
12.811332 ABIN4901871 ELISA IHC (p) WB Mouse IgG1 Log in to see 4E7 0
12.811332 ABIN1689940 IHC (p) WB Rabbit Log in to see Polyclonal 0
11.7556715 ABIN291872 IF IHC IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal 0
11.7556715 ABIN218314 IHC IHC (p) WB Rabbit IgG AA 249-266 Log in to see Polyclonal 0
11.7556715 ABIN499041 IHC (p) WB Rabbit Log in to see Polyclonal 0
11.5 ABIN735188 IF (cc) IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal 1
10 ABIN2888671 ELISA IF IHC IHC (p) WB Rabbit IgG AA 361-410 Log in to see Polyclonal 0
10 ABIN3031585 ICC IHC (p) WB Rabbit IgG AA 455-469 Log in to see Polyclonal 0
9.997421 ABIN4330010 ICC IF IHC IHC (p) IP WB Rabbit IgG Center Log in to see Polyclonal 0
9.997421 ABIN4330011 ICC IF IHC IHC (p) IP WB Rabbit IgG Center Log in to see Polyclonal 0
8.7556715 ABIN1108014 IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal 0
8.7556715 ABIN615033 IHC (p) WB Rabbit N-Term Log in to see Polyclonal 0
8.5 ABIN108550 FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG3 kappa AA 598-611 Log in to see 133A2 2
7 ABIN2879094 ELISA IHC IHC (p) WB Rabbit IgG AA 212-261, Cleaved-Asp230 Log in to see Polyclonal 0

General

Antigen Lamin A/C (LMNA) Antibodies
Epitope Center
(37), (25), (25), (20), (20), (18), (17), (12), (11), (11), (9), (9), (8), (7), (7), (6), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(449), (272), (236), (99), (53), (49), (25), (22), (17), (10), (10), (9), (5), (5), (4), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Host Rabbit
(239), (218), (5), (3)
Clonality
Polyclonal
Conjugate This Lamin A/C antibody is un-conjugated
(13), (12), (10), (7), (7), (6), (6), (6), (6), (6), (6), (6), (5), (5), (5), (5), (4), (4), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(415), (206), (197), (154), (121), (111), (77), (72), (53), (17), (15), (11), (2), (2), (1), (1), (1), (1)
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Product Details anti-Lamin A/C Antibody

Target Details Lamin A/C Application Details Handling Images
Characteristics Rabbit Polyclonal antibody to Lamin A + C
Lamin A + C antibody
Purification Purified by antigen-affinity chromatography.
Immunogen Recombinant protein encompassing a sequence within the center region of human Lamin A/C. The exact sequence is proprietary.
Isotype IgG
Plasmids, Primers & others

Target Details Lamin A/C

Product Details anti-Lamin A/C Antibody Application Details Handling Images back to top
Antigen
Alternative Name Lamin A + C (LMNA Antibody Abstract)
Background The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Through alternate splicing, this gene encodes three type A lamin isoforms. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.

Cellular Localization: Nucleus
Molecular Weight 74 kDa
Gene ID 4000
Pathways Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus

Application Details

Product Details anti-Lamin A/C Antibody Target Details Lamin A/C Handling Images back to top
Application Notes Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Immunoprecipitation 1:66-1:500* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Immunoprecipitation1:66-1:500* Western blot1:500-1:3000*
Comment

Positive Control: HeLa nucleus , C2C12 , NIH-3T3

Restrictions For Research Use only

Handling

Product Details anti-Lamin A/C Antibody Target Details Lamin A/C Application Details Images back to top
Format Liquid
Concentration 0.27 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Images

Product Details anti-Lamin A/C Antibody Target Details Lamin A/C Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Lamin A/C (LMNA) (Center) antibody (ABIN2854942) IHC-P Image Lamin A + C antibody detects Lamin A + C protein at nuclear envelope on m...
Immunohistochemistry (IHC) image for anti-Lamin A/C (LMNA) (Center) antibody (ABIN2854942) IHC-P Image Lamin A + C antibody detects Lamin A + C protein at nuclear envelope on m...
Western Blotting (WB) image for anti-Lamin A/C (LMNA) (Center) antibody (ABIN2854942) WB Image Whole cell extract (30 μg) was separated by 7.5% SDS-PAGE, and the membrane ...
Immunofluorescence (IF) image for anti-Lamin A/C (LMNA) (Center) antibody (ABIN2854942) ICC/IF Image Confocal immunofluorescence analysis (Olympus FV10i) of methanol-fixed H...
Western Blotting (WB) image for anti-Lamin A/C (LMNA) (Center) antibody (ABIN2854942) WB Image Lamin A + C antibody detects Lamin A + C protein by Western blot analysis. A...
Immunoprecipitation (IP) image for anti-Lamin A/C (LMNA) (Center) antibody (ABIN2854942) IP Image Immunoprecipitation of Lamin A + C protein from HeLa whole cell extracts usi...
Immunohistochemistry (IHC) image for anti-Lamin A/C (LMNA) (Center) antibody (ABIN2854942) IHC-P Image Lamin A + C antibody detects Lamin A + C protein at nuclear envelope on m...
Immunohistochemistry (IHC) image for anti-Lamin A/C (LMNA) (Center) antibody (ABIN2854942) IHC-P Image Lamin A + C antibody detects Lamin A + C protein at membrane on U87 xenog...
Western Blotting (WB) image for anti-Lamin A/C (LMNA) (Center) antibody (ABIN2854942) WB Image Lamin A + C antibody detects Lamin A + C protein by Western blot analysis. A...
Immunohistochemistry (IHC) image for anti-Lamin A/C (LMNA) (Center) antibody (ABIN2854942) IHC-P Image Lamin A + C antibody detects Lamin A + C protein at nuclear envelope on h...