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|Antigen||Lamin A/C (LMNA) Antibodies|
|Epitope||AA 249-266 Alternatives|
|Reactivity||Dog (Canine), Hamster, Horse (Equine), Human, Monkey, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus) Alternatives|
|Conjugate||This Lamin A/C antibody is un-conjugated Alternatives|
Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|Supplier||Log in to see|
Product Details anti-Lamin A/C AntibodyTarget Details Lamin A/C Application Details Handling Images
|Specificity||Because of immunogen's 100 % homology with Isoforms 1, 4, 5, 6, ADelta10 and C of Prelamin-A/C, this is expected to detect multiple bands in WB.|
|Predicted Reactivity||Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Horse, Rabbit, Pig (100%) Bovine, Opossum (94%) Bat, Platypus (88%).|
A synthetic peptide corresponding to amino acids 249-265 C-RAQHEDQVEQYKKELEK of Human Lamin A/C. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Horse, Rabbit, Pig (100%), Bovine, Opossum (94%), Bat, Platypus (88%).
Type of Immunogen: Synthetic peptide
|Plasmids, Primers & others|
Target Details Lamin A/CProduct Details anti-Lamin A/C Antibody Application Details Handling Images back to top
|Alternative Name||LMNA / Lamin A/C (LMNA Antibody Abstract)|
Name/Gene ID: LMNA
Synonyms: LMNA, 70 kDa lamin, CDCD1, CMD1A, EMD2, FPLD, IDC, FPL, FPLD2, Lamin A/C, Lamin, LFP, LMNC, LMN1, LMNL1, HGPS, Prelamin-A/C, PRO1, Lamin A, Lamin A/C-like 1, LGMD1B, CDDC, CMT2B1, LDP1
This antibody detects: LMNA / Lamin A+C
|Pathways||Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus|
Application DetailsProduct Details anti-Lamin A/C Antibody Target Details Lamin A/C Handling Images back to top
Approved: IHC, IHC-P (1:100), WB (1:500 - 1:1000)
Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 1:100.
Target Species of Antibody: Human
|Restrictions||For Research Use only|
HandlingProduct Details anti-Lamin A/C Antibody Target Details Lamin A/C Application Details Images back to top
|Buffer||PBS containing 0.05 % BSA and 0.05 % sodium azide|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage||4 °C,-80 °C|
Short term: 4°C
Long term: -70°C.
ImagesProduct Details anti-Lamin A/C Antibody Target Details Lamin A/C Application Details Handling back to top