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Submit your validation data for this product and get a full refund. I want to validate this productRelevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
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3.2908103 | ABIN2782595 | WB | Rabbit | Middle Region | Log in to see | Polyclonal | 1 | |||
3.2908103 | ABIN2856712 | IP IHC (p) WB | Rabbit | IgG | Internal Region | Log in to see | Polyclonal | 0 | ||
3.2908103 | ABIN443145 | IHC IHC (p) IP WB | Rabbit | IgG | Center | Log in to see | Polyclonal | 0 | ||
3.2908103 | ABIN390698 | WB | Rabbit | Ig Fraction | AA 476-504, C-Term | Log in to see | Polyclonal | 2 | ||
3.2908103 | ABIN497969 | EIA WB | Rabbit | Ig Fraction | C-Term, AA 483-512 | Log in to see | Polyclonal | 1 | ||
3.2908103 | ABIN3044232 | IHC (fro) IHC (p) WB | Rabbit | IgG | AA 580-597, C-Term | Log in to see | Polyclonal | 0 | ||
3.2908103 | ABIN2563696 | IF IHC WB | Rabbit | IgG | Log in to see | Polyclonal | 0 | |||
3.2908103 | ABIN4330078 | ICC IF IHC IHC (p) IP WB | Mouse | IgG2a | Center | Log in to see | 144 | 0 | ||
3.2908103 | ABIN630994 | WB | Rabbit | N-Term | Log in to see | Polyclonal | 0 | |||
3.2908103 | ABIN631003 | WB | Rabbit | Middle Region | Log in to see | Polyclonal | 0 | |||
3.2908103 | ABIN2459013 | ELISA WB | Rabbit | Log in to see | Polyclonal | 0 | ||||
3.2908103 | ABIN2462974 | ELISA WB | Rabbit | Log in to see | Polyclonal | 0 | ||||
3.2908103 | ABIN4330077 | ICC IF IHC IHC (p) WB | Rabbit | IgG | Center | Log in to see | Polyclonal | 0 | ||
3.2908103 | ABIN5681578 | ELISA FACS ICC IF IHC WB | Mouse | IgG2b | AA 401-600 | Log in to see | 2E2F4 | 0 | ||
3.2908103 | ABIN4330079 | WB | Mouse | IgG1 | Log in to see | 2C6 | 0 | |||
3.2908103 | ABIN2966775 | IC IF IHC WB | Rabbit | Log in to see | Polyclonal | 0 | ||||
3.2908103 | ABIN3031589 | ELISA WB | Rabbit | Ig Fraction | AA 476-504 | Log in to see | Polyclonal | 0 | ||
3.2908103 | ABIN4330080 | IHC WB | Rabbit | IgG | Log in to see | Polyclonal | 0 | |||
3.2908103 | ABIN3031588 | IHC (fro) IHC (p) WB | Rabbit | IgG | AA 580-597 | Log in to see | Polyclonal | 0 | ||
3.2908103 | ABIN5542337 | ELISA FACS ICC IHC WB | Mouse | IgG2b | AA 401-600 | Log in to see | 2E2F4 | 0 |
General |
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Antigen | Lamin B2 (LMNB2) Antibodies |
Epitope | N-Term Alternatives |
Reactivity | Cow (Bovine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus) Alternatives |
Host | Rabbit Alternatives |
Clonality | |
Conjugate | This Lamin B2 antibody is un-conjugated Alternatives |
Application |
Western Blotting (WB)
Alternatives
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2 references available |
Supplier | Log in to see |
Product Details anti-Lamin B2 AntibodyTarget Details Lamin B2 Application Details Handling References for anti-Lamin B2 antibody (ABIN2782594) Images |
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Blocking Peptide | Blocking peptide for this product available: ABIN979359 |
Sequence | MATPLPGRAG GPATPLSPTR LSRLQEKEEL RELNDRLAHY IDRVRALELE |
Predicted Reactivity | Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 85%, Rat: 92% |
Characteristics | This is a rabbit polyclonal antibody against LMNB2. It was validated on Western Blot using a cell lysate as a positive control. |
Purification | Affinity Purified |
Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human LMNB2 |
Target Details Lamin B2Product Details anti-Lamin B2 Antibody Application Details Handling References for anti-Lamin B2 antibody (ABIN2782594) Images back to top |
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Antigen | |
Alternative Name | LMNB2 (LMNB2 Antibody Abstract) |
Background |
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. LMNB2 is one of the two B type proteins, B2.The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B2. This gene is in a head-to-tail orientation with the gene for the translocase of inner mitochondrial membrane 13 homolog gene. Alias Symbols: LAMB2, LMN2, MGC2721 Protein Interaction Partner: UBC, GPRASP2, SUZ12, EED, RNF2, LMNA, PAN2, VCP, UBD, SIRT7, ELAVL1, SVIL, BANF1, PRKCD, LMNB2, TMPO, XRCC5, ORC2, Protein Size: 600 |
Molecular Weight | 68 kDa |
Gene ID | 84823 |
NCBI Accession | NM_032737, NP_116126 |
UniProt | Q03252 |
Pathways | Apoptosis, Caspase Cascade in Apoptosis |
Application DetailsProduct Details anti-Lamin B2 Antibody Target Details Lamin B2 Handling References for anti-Lamin B2 antibody (ABIN2782594) Images back to top |
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Application Notes | Optimal working dilutions should be determined experimentally by the investigator. |
Comment |
Antigen size: 600 AA |
Restrictions | For Research Use only |
HandlingProduct Details anti-Lamin B2 Antibody Target Details Lamin B2 Application Details References for anti-Lamin B2 antibody (ABIN2782594) Images back to top |
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Format | Liquid |
Concentration | Lot specific |
Buffer | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose. |
Preservative | Sodium azide |
Precaution of Use | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Handling Advice | Avoid repeated freeze-thaw cycles. |
Storage | -20 °C |
Storage Comment | For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
References for anti-Lamin B2 antibody (ABIN2782594)Product Details anti-Lamin B2 Antibody Target Details Lamin B2 Application Details Handling Images back to top |
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Product cited in: |
Jacinto, Benner, Hetzer: "The nucleoporin Nup153 regulates embryonic stem cell pluripotency through gene silencing." in: Genes & development, Vol. 29, Issue 12, pp. 1224-38, 2015 Tsai, Wang, Heidinger, Shumaker, Adam, Goldman, Zheng: "A mitotic lamin B matrix induced by RanGTP required for spindle assembly." in: Science (New York, N.Y.), Vol. 311, Issue 5769, pp. 1887-93, 2006 |
ImagesProduct Details anti-Lamin B2 Antibody Target Details Lamin B2 Application Details Handling References for anti-Lamin B2 antibody (ABIN2782594) back to top |
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Supplier Images |