The sensitivity, minimum detectable dose of human TRAIL R3 using this TRAIL R3 ELISA kit was found to be 147 pg/mL. This was determined by adding 3 standard deviations to the mean OD obtained when the zero standard was assayed 32 times.
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TNFRSF10C Antigen Profile
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.
Alternative names and synonyms associated with TNFRSF10C
TNF receptor superfamily member 10c (TNFRSF10C) ELISA Kit
CD263 ELISA Kit
DCR1 ELISA Kit
DCR1-TNFR ELISA Kit
LIT ELISA Kit
TRAIL-R3 ELISA Kit
TRAILR3 ELISA Kit
TRID ELISA Kit
TNFRSF10C ELISA Kit
Protein level used designations for TNFRSF10C
TNF-related apoptosis-inducing ligand receptor 3
, antagonist decoy receptor for TRAIL/Apo-2L
, cytotoxic TRAIL receptor-3
, decoy TRAIL receptor without death domain
, decoy receptor 1
, lymphocyte inhibitor of TRAIL
, tumor necrosis factor receptor superfamily member 10C
, tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain