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Submit your validation data for this product and get a full refund. I want to validate this productRelevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
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1 | ABIN1169231 | ICC FACS IP IHC | Mouse | IgG1 | Log in to see | HS402 | 3 | |||
1 | ABIN201906 | ICC IHC WB | Rabbit | AA 249-263 | Log in to see | Polyclonal | 0 | |||
1 | ABIN5080282 | ICC IF | Rabbit | IgG | Log in to see | Polyclonal | 0 | |||
1 | ABIN1820459 | ICC ELISA WB | Rabbit | IgG | AA 249-263 | Log in to see | Polyclonal | 0 | ||
1 | ABIN5688395 | FACS ICC IHC IP | Mouse | IgG1 | Log in to see | HS402 | 0 | |||
1 | ABIN2629596 | ICC IHC (fro) FACS IP | Mouse | IgG1 | Log in to see | HS402 | 0 | |||
1 | ABIN2964494 | ICC FACS IP IHC | Mouse | IgG1 | Log in to see | HS402 | 0 |
General |
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Antigen | Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) Antibodies |
Epitope | Center Alternatives |
Reactivity | Human, Mouse (Murine), Rat (Rattus) Alternatives |
Host | Rabbit Alternatives |
Clonality | |
Conjugate | This TNFRSF10D antibody is un-conjugated Alternatives |
Application |
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Alternatives
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19 references available |
Supplier | Log in to see |
Product Details anti-TNFRSF10D AntibodyTarget Details TNFRSF10D Application Details Handling References for anti-TNFRSF10D antibody (ABIN4361837) Images |
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Purification | Immunogen affinity purified |
Immunogen | Antibody was raised against a 15 amino acid peptide near the center of human DcR2. The immunogen is located within amino acids 230 - 280 of DcR2. |
Target Details TNFRSF10DProduct Details anti-TNFRSF10D Antibody Application Details Handling References for anti-TNFRSF10D antibody (ABIN4361837) Images back to top |
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Antigen | |
Alternative Name | TRAIL R4/TNFRSF10D/DcR2 (TNFRSF10D Antibody Abstract) |
Background | Gene Symbol: TNFRSF10D |
Molecular Weight | Theoretical MW: 36 kDa |
Gene ID | 8793 |
UniProt | Q9UBN6 |
Pathways | Apoptosis |
Application DetailsProduct Details anti-TNFRSF10D Antibody Target Details TNFRSF10D Handling References for anti-TNFRSF10D antibody (ABIN4361837) Images back to top |
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Application Notes | Western Blot 1:100-1:2000, ELISA 1:100-1:2000, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 1:10-1:2000, Immunohistochemistry-ParaffinDcR2 antibody can be used for detection of DcR2 expression by Western blot at 1:1000 to 1:2000 dilution. |
Comment |
The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo. |
Restrictions | For Research Use only |
HandlingProduct Details anti-TNFRSF10D Antibody Target Details TNFRSF10D Application Details References for anti-TNFRSF10D antibody (ABIN4361837) Images back to top |
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Format | Liquid |
Concentration | 1 mg/mL |
Buffer |
PBS Buffer contains: 0.02 % Sodium Azide |
Preservative | Sodium azide |
Precaution of Use | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Storage | 4 °C,-20 °C |
Storage Comment | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
References for anti-TNFRSF10D antibody (ABIN4361837)Product Details anti-TNFRSF10D Antibody Target Details TNFRSF10D Application Details Handling Images back to top |
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Product cited in: |
Gupta, Francis, Nair, Mo, Aggarwal et al.: "Azadirone, a limonoid tetranortriterpene, induces death receptors and sensitizes human cancer cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) through a p53 ..." in: The Journal of biological chemistry, Vol. 288, Issue 45, pp. 32343-56, 2013 (Sample species: Human). Further details: Western Blotting Allen, Ferrini, Dicker, Batzer, Chen, Oltean, Lin, Renshaw, Kretz-Rommel, El-Deiry: "Targeting TRAIL death receptor 4 with trivalent DR4 Atrimer complexes." in: Molecular cancer therapeutics, Vol. 11, Issue 10, pp. 2087-95, 2012 Nagane, Shimizu, Mori, Kataoka, Shiokawa: "Predominant antitumor effects by fully human anti-TRAIL-receptor 2 (DR5) monoclonal antibodies in human glioma cells in vitro and in vivo." in: Neuro-oncology, Vol. 12, Issue 7, pp. 687-700, 2011 (Sample species: Human). Further details: Western Blotting Zhang, Wang, Liu, Guan, Du: "Regulation of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by DJ-1 in thyroid cancer cells." in: Endocrine-related cancer, Vol. 15, Issue 2, pp. 535-44, 2008 (Sample species: Human). Further details: Western Blotting Lunghi, Giuliani, Mazzera, Lombardi, Ricca, Corradi, Cantoni, Salvatore, Riccioni, Costanzo, Testa, Levrero, Rizzoli, Bonati: "Targeting MEK/MAPK signal transduction module potentiates ATO-induced apoptosis in multiple myeloma cells through multiple signaling pathways." in: Blood, Vol. 112, Issue 6, pp. 2450-62, 2008 (Sample species: Human). Further details: Western Blotting Taniguchi, Yoshida, Horinaka, Yasuda, Goda, Konishi, Wakada, Kataoka, Yoshikawa, Sakai: "Baicalein overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance via two different cell-specific pathways in cancer cells but not in normal cells." in: Cancer research, Vol. 68, Issue 21, pp. 8918-27, 2008 Further details: Western Blotting Kawakubo, Okamoto, Iwata, Shin, Okamoto, Yasukochi, Nakayama, Kadowaki, Tsukuba, Yamamoto: "Cathepsin E prevents tumor growth and metastasis by catalyzing the proteolytic release of soluble TRAIL from tumor cell surface." in: Cancer research, Vol. 67, Issue 22, pp. 10869-78, 2007 Further details: Western Blotting Liu, Yue, Khuri, Sun: "Decoy receptor 2 (DcR2) is a p53 target gene and regulates chemosensitivity." in: Cancer research, Vol. 65, Issue 20, pp. 9169-75, 2005 Poulaki, Mitsiades, McMullan, Fanourakis, Negri, Goudopoulou, Halikias, Voutsinas, Tseleni-Balafouta, Miller, Mitsiades: "Human retinoblastoma cells are resistant to apoptosis induced by death receptors: role of caspase-8 gene silencing." in: Investigative ophthalmology & visual science, Vol. 46, Issue 1, pp. 358-66, 2004 Fan, Zou, Song, Wei: "Synergistic antitumor activity of TRAIL combined with chemotherapeutic agents in A549 cell lines in vitro and in vivo." in: Cancer chemotherapy and pharmacology, Vol. 55, Issue 2, pp. 189-96, 2004 Koyama et al.: "Flow cytometric measurement of tumor necrosis factor-related apoptosis-inducing ligand and its receptors in gastric epithelium and infiltrating mucosal lymphocytes in Helicobacter pylori-associated ..." in: Journal of gastroenterology and hepatology, Vol. 18, Issue 7, pp. 763-70, 2003 Further details: Flow Cytometry Mitsiades, Mitsiades, Poulaki, Anderson, Treon: "Intracellular regulation of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human multiple myeloma cells." in: Blood, Vol. 99, Issue 6, pp. 2162-71, 2002 Poulaki, Mitsiades, Kotoula, Tseleni-Balafouta, Ashkenazi, Koutras, Mitsiades: "Regulation of Apo2L/tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in thyroid carcinoma cells." in: The American journal of pathology, Vol. 161, Issue 2, pp. 643-54, 2002 Mitsiades, Mitsiades, Poulaki, Schlossman, Akiyama, Chauhan, Hideshima, Treon, Munshi, Richardson, Anderson: "Activation of NF-kappaB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implications." in: Oncogene, Vol. 21, Issue 37, pp. 5673-83, 2002 (Sample species: Human). Further details: Cell Sorting Koyama, Koike, Adachi: "Expression of TNF-related apoptosis-inducing ligand (TRAIL) and its receptors in gastric carcinoma and tumor-infiltrating lymphocytes: a possible mechanism of immune evasion of the tumor." in: Journal of cancer research and clinical oncology, Vol. 128, Issue 2, pp. 73-9, 2002 Mitsiades, Poulaki, Mitsiades, Tsokos: "Ewing's sarcoma family tumors are sensitive to tumor necrosis factor-related apoptosis-inducing ligand and express death receptor 4 and death receptor 5." in: Cancer research, Vol. 61, Issue 6, pp. 2704-12, 2001 Mitsiades, Treon, Mitsiades, Shima, Richardson, Schlossman, Hideshima, Anderson: "TRAIL/Apo2L ligand selectively induces apoptosis and overcomes drug resistance in multiple myeloma: therapeutic applications." in: Blood, Vol. 98, Issue 3, pp. 795-804, 2001 Basile, Zacny, Münger et al.: "The cytokines tumor necrosis factor-alpha (TNF-alpha ) and TNF-related apoptosis-inducing ligand differentially modulate proliferation and apoptotic pathways in human keratinocytes expressing the ..." in: The Journal of biological chemistry, Vol. 276, Issue 25, pp. 22522-8, 2001 (Sample species: Human). Further details: Western Blotting Mitsiades, Poulaki, Tseleni-Balafouta, Koutras, Stamenkovic: "Thyroid carcinoma cells are resistant to FAS-mediated apoptosis but sensitive to tumor necrosis factor-related apoptosis-inducing ligand." in: Cancer research, Vol. 60, Issue 15, pp. 4122-9, 2000 |