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Urinary DcR2 (show CCR6 ELISA Kits) could potentially serve as a novel biomarker for tubulointerstitial injury and may reflect senescence of renal proximal tubular cells in diabetic nephropathy.
Results identified epigenetic inactivation of TNFRSF10C (show TNFRSF10C ELISA Kits) and TNFRSF10D in majority of cervical cancer cases.
This study identified TNFRSF10D DNA methylation (show HELLS ELISA Kits) status as an independent prognostic biomarker for relapse-free survival and overall mortality in non-metastatic melanoma patients.
The membrane expression of the TRAIL receptors DR4, DR5 (show TNFRSF10B ELISA Kits), DcR1 (show TNFRSF10C ELISA Kits) and DcR2 (show CCR6 ELISA Kits) is greater in normal endometrium than endometrioid adenocarcinoma (EAC (show CYLD ELISA Kits)). The level of the receptors in EAC (show CYLD ELISA Kits) is not dependent on grading and staging and does not predict survival.
the results presented here claim for a relevant impact of aberrant methylation of decoy receptors in melanoma and allow to understand how the silencing of DcR1 (show TNFRSF10C ELISA Kits) and DcR2 (show CCR6 ELISA Kits) is related to melanomagenesis.
transcript levels of UCHL1 (show UCHL1 ELISA Kits), COL1A2 (show COL1A2 ELISA Kits), THBS1 (show THBS1 ELISA Kits) and TNFRSF10D were inversely correlated with promoter methylation
TRAIL receptor-4 expression profiles on T cells might be important in revelation of rheumatoid arthritis pathogenesis.
ANT2 (show SLC25A5 ELISA Kits) shRNA treatment sensitized MCF7, T47 D, and BT474 cells to TRAIL-induced apoptosis by up-regulating the expression of TRAIL death receptors 4 and 5 (DR4 and DR5 (show TNFRSF10B ELISA Kits)) and down-regulating the TRAIL decoy receptor 2 (DcR2).
these results demonstrated that hypoxia-inducible factor 1alpha played a crucial role in regulating the transcription of DcR2 (show CCR6 ELISA Kits).
TNF-related apoptosis-inducing ligand (TRAIL (show TNFSF10 ELISA Kits)) is not constitutively expressed in the human brain, whereas both apoptosis-mediating and apoptosis-blocking TRAIL receptors are found on neurons, astrocytes, and oligodendrocytes
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain, a transmembrane domain, and a truncated cytoplamic death domain. This receptor does not induce apoptosis, and has been shown to play an inhibitory role in TRAIL-induced cell apoptosis.
tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
, TNF receptor-related receptor for TRAIL
, TNF-related apoptosis-inducing ligand receptor 4
, TRAIL receptor 4
, TRAIL receptor with a truncated death domain
, decoy receptor 2
, tumor necrosis factor receptor superfamily member 10D