anti-Mouse (Murine) TNFRSF12A antibody for Western Blotting

Recommended TNFRSF12A Antibody (supplied by: Log in to see )

Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) Antibodies
  • CD266
  • FN14
  • TWEAKR
  • AI255180
  • C87282
  • Fn14
  • HPIP
  • TWEAK-R
  • TweakR
  • TNF receptor superfamily member 12A
  • tumor necrosis factor receptor superfamily, member 12a
  • TNFRSF12A
  • Tnfrsf12a
Reactivity
Human, Mouse (Murine)
91
56
29
2
2
2
2
1
1
1
1
Host
Mouse
51
40
8
1
Clonality
Monoclonal
Conjugate
This TNFRSF12A antibody is conjugated to PE
10
4
4
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Functional Studies (Func), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Flow Cytometry (FACS), Western Blotting (WB)
56
43
25
16
13
10
10
10
3
2
2
2
2
1
1
1
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see

Available images

Catalog No. ABIN2749122
$ 497.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
16.285042 ABIN2749025 Func IHC (f) FACS WB Mouse IgG2b Log in to see ITEM-4 3
16.285042 ABIN2749054 Func IHC (f) FACS WB Mouse IgG2b Log in to see ITEM-4 3
7.694713 ABIN2784518 WB Rabbit N-Term Log in to see Polyclonal 0
7.694713 ABIN2421485 IHC ELISA WB Rabbit IgG Log in to see Polyclonal 0
7.694713 ABIN2428037 ELISA WB Rabbit IgG Log in to see Polyclonal 0
7 ABIN490868 WB Rabbit IgG AA 104-118 Log in to see Polyclonal 0
5.5 ABIN2479564 IHC (fro) FACS WB Mouse IgG2b Log in to see ITEM-4 1
4 ABIN4900099 CyTOF ELISA (Capture) FACS IHC WB Goat IgG AA 28-79 Log in to see Polyclonal 0
1 ABIN1819127 FACS IHC IHC (fro) WB PE Mouse IgG2b Log in to see ITEM-4 0
1 ABIN4900098 CyTOF FACS WB Rat IgG2a AA 28-79 Log in to see 314636 0
1 ABIN1820056 FACS IHC IHC (fro) WB FITC Mouse IgG2b Log in to see ITEM-4 0
1 ABIN3199690 FACS Func IHC (fro) WB Mouse IgG2b Log in to see ITEM-4 0
1 ABIN2574953 WB Rabbit AA 1-75 Log in to see Polyclonal 0
1 ABIN3199692 FACS Func IHC (fro) WB PE Mouse IgG2b Log in to see ITEM-4 0
1 ABIN3199691 FACS Func IHC (fro) WB Mouse IgG2b Log in to see ITEM-4 0
1 ABIN5540154 FACS Func IHC (fro) WB Mouse IgG2b Log in to see ITEM-4 0
1 ABIN5540153 FACS Func IHC (fro) WB Mouse IgG2b Log in to see ITEM-4 0
1 ABIN3037011 FACS IHC WB Mouse IgG2b Log in to see 0
1 ABIN6041607 ELISA WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN6039994 ELISA IHC WB Rabbit IgG Log in to see Polyclonal 0

General

Antigen Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) Antibodies
Reactivity Human, Mouse (Murine)
(91), (56), (29), (2), (2), (2), (2), (1), (1), (1), (1)
Host Mouse
(51), (40), (8), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This TNFRSF12A antibody is conjugated to PE
(10), (4), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Functional Studies (Func), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Flow Cytometry (FACS), Western Blotting (WB)
(56), (43), (25), (16), (13), (10), (10), (10), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 3 references available
Supplier Log in to see

Product Details anti-TNFRSF12A Antibody

Target Details TNFRSF12A Application Details Handling References for anti-TNFRSF12A antibody (ABIN2749122) Images
Specificity The mouse monoclonal antibody ITEM-4 recognizes CD266 / TWEAK R, a TNFR superfamily receptor for CD255 / TWEAK, a TNF-like weak inducer of apoptosis.
Cross-Reactivity (Details) Human, Mouse
Immunogen human CD266-transfected P815 cells
Clone ITEM-4
Isotype IgG2b
Plasmids, Primers & others

Target Details TNFRSF12A

Product Details anti-TNFRSF12A Antibody Application Details Handling References for anti-TNFRSF12A antibody (ABIN2749122) Images back to top
Antigen
Alternative Name CD266 / TWEAK R (TNFRSF12A Antibody Abstract)
Background CD266 / TWEAK R (TNFRSF12A), also known as FN14 (fibroblast growth factor-inducible 14) is a receptor for CD255 / TWEAK, the TNF-like weak inducer of apoptosis. CD266 is expressed on endothelial cells, as well as on some cancer tissues, and plays a role in CD255-induced endothelial cell migration, proliferation, and angiogenesis. The CD255-CD266 interaction, or antibody-mediated triggering of CD266 is also able to induce apoptosis and necrosis in CD266-positive cells (including tumor cells), which might have therapeutic potential.
Pathways Apoptosis, Regulation of Cell Size

Application Details

Product Details anti-TNFRSF12A Antibody Target Details TNFRSF12A Handling References for anti-TNFRSF12A antibody (ABIN2749122) Images back to top
Application Notes The reagent is designed for Flow Cytometry analysis.
Comment

The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.

Restrictions For Research Use only

Handling

Product Details anti-TNFRSF12A Antibody Target Details TNFRSF12A Application Details References for anti-TNFRSF12A antibody (ABIN2749122) Images back to top
Buffer The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.

References for anti-TNFRSF12A antibody (ABIN2749122)

Product Details anti-TNFRSF12A Antibody Target Details TNFRSF12A Application Details Handling Images back to top
Product cited in:

Yoriki, Akashi, Sho, Nomi, Yamato, Hotta, Takayama, Matsumoto, Wakatsuki, Migita, Yagita, Nakajima: "Therapeutic potential of the TWEAK/Fn14 pathway in intractable gastrointestinal cancer." in: Experimental and therapeutic medicine, Vol. 2, Issue 1, pp. 103-108, 2012

Roos, Wicovsky, Müller, Salzmann, Rosenthal, Kalthoff, Trauzold, Seher, Henkler, Kneitz, Wajant: "Soluble and transmembrane TNF-like weak inducer of apoptosis differentially activate the classical and noncanonical NF-kappa B pathway." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 3, pp. 1593-605, 2010

Nakayama, Ishidoh, Kojima, Harada, Kominami, Okumura, Yagita: "Fibroblast growth factor-inducible 14 mediates multiple pathways of TWEAK-induced cell death." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 1, pp. 341-8, 2002

Images

Product Details anti-TNFRSF12A Antibody Target Details TNFRSF12A Application Details Handling References for anti-TNFRSF12A antibody (ABIN2749122) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) antibody (PE) (ABIN2749122) Surface staining of CD266-transfected L51784 cells with anti-human CD266 (ITEM-4) PE.