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anti-Human YWHAQ Antibodies:
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Human Polyclonal YWHAQ Primary Antibody for WB - ABIN2477179
Boston, Jackson, Kynoch, Thompson: Purification, properties, and immunohistochemical localisation of human brain 14-3-3 protein. in Journal of neurochemistry 1982
Show all 2 Pubmed References
Human Polyclonal YWHAQ Primary Antibody for ELISA, WB - ABIN451588
Howlett, Sakamoto, Garnham, Cameron-Smith, Hargreaves: Resistance exercise and insulin regulate AS160 and interaction with 14-3-3 in human skeletal muscle. in Diabetes 2007
Cow (Bovine) Monoclonal YWHAQ Primary Antibody for EIA, WB - ABIN264385
Patel, Cummings, Batchelor, Hill, Dubois, Mellits, Frankel, Connerton: Host protein interactions with enteropathogenic Escherichia coli (EPEC): 14-3-3tau binds Tir and has a role in EPEC-induced actin polymerization. in Cellular microbiology 2005
Amphibian Polyclonal YWHAQ Primary Antibody for IHC (p), IP - ABIN2477177
Aitken: 14-3-3 proteins: a historic overview. in Seminars in cancer biology 2006
Chk1 (show CHEK1 Antibodies) and 14-3-3 proteins cooperate to inactivate the transcriptional repressor functions of atypical E2F (show E2F1 Antibodies) proteins. This mechanism might be of particular importance to cancer cells, since they are exposed frequently to DNA-damaging therapeutic reagents.
results suggest that PKC (show PRRT2 Antibodies) SUMOylation is an important regulator of the 14-3-3 and GluK2a protein complex and may contribute to regulate the decay kinetics of kainate receptor-excitatory postsynaptic currents
Results show that 14-3-3zeta promotes cell proliferation, migration and invasion in lung adenocarcinoma. 14-3-3zeta upregulates MUC1 expression through enhancing MUC1/NFkappaB feedback loop. Its high expression is associated with poor survival in lung adenocarcinoma patients.
TGFbetaR1 signaling was involved in 14-3-3zeta (show YWHAZ Antibodies)-mediated cell proliferation and metastasis of lung squamous cell carcinoma cells.
Loss of Par3 (show F2RL2 Antibodies) promotes metastatic behavior in lung adenocarcinoma cells through 14-3-3zeta (show YWHAZ Antibodies) protein.
this study reveals that 14-3-3zeta (show YWHAZ Antibodies) plays a critical role in Wnt5a (show WNT5A Antibodies)/ROR1 (show ROR1 Antibodies) signaling, leading to enhanced CLL migration and proliferation.
AKT (show AKT1 Antibodies) and 14-3-3 proteins down-regulate the activity of several BCR (show BCR Antibodies)-associated components, including BTK (show BTK Antibodies), BLNK (show BLNK Antibodies) and SYK (show SYK Antibodies) and also inhibit SYK's interaction with Importin 7 (show IPO7 Antibodies)
Our results indicate that TRIM25 (show TRIM25 Antibodies) is associated with cisplatin resistance and 14-3-3sigma-MDM2 (show MDM2 Antibodies)-p53 (show TP53 Antibodies) signaling pathway is involved in this process, suggesting targeting TRIM25 (show TRIM25 Antibodies) may be a potential strategy for the reversal of cisplatin resistance.
Up-regulation of 14-3-3zeta (show YWHAZ Antibodies) in response to pVHL (show VHL Antibodies) is important for the recruitment of PI3K (show PIK3CA Antibodies) to the cell membrane and for stabilization of soluble beta-catenin (show CTNNB1 Antibodies).
The 14-3-3 family is dysregulated in schizophrenia, perhaps owing to specific regulatory mechanisms; the expression of the 14-3-3 epsilon (show YWHAE Antibodies), theta and zeta isoforms could be useful indicators of disease severity.
analysis of phosphorylation-dependent interactions of AQP2 (show AQP2 Antibodies) with 14-3-3theta; and -zeta
Data show that IkappaB kinase (show CHUK Antibodies) (IKK (show CHUK Antibodies)) phosphorylation of the TPL-2 (show MAP3K8 Antibodies) kinase (TPL-2 (show MAP3K8 Antibodies)) induces 14-3-3 association with TPL-2 (show MAP3K8 Antibodies), stimulating its MEK (show MDK Antibodies) kinase activity, which is essential for TPL-2 (show MAP3K8 Antibodies) activation of ERK-1 (show MAPK3 Antibodies)/2.
There is a scaffolding role for 14-3-3theta in assisting the delivery of Cx43 (show GJA1 Antibodies) and integrin alpha5 to the plasma membrane for the formation of mechanosensitive hemichannels in osteocytes.
14-3-3 negatively regulates the RGC downstream of the PI3-kinase (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) signaling pathway
14-3-3 theta is a new and important regulatory protein (show TGFB1 Antibodies) in the TLR-2 and TLR-4 (show TLR4 Antibodies) signaling suppressing the MyD88 (show MYD88 Antibodies)-dependent pathway
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.
14-3-3 protein tau
, 14-3-3 tau
, 14-3-3 theta
, 14-3-3 protein theta
, 14-3-3 protein T-cell
, tyrosine 3/tryptophan 5 -monooxygenase activation protein, theta polypeptide
, cerebellar 14-3-3 theta protein
, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 2