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CASC5 Proteins

(Cancer Susceptibility Candidate 5 (CASC5))

The protein encoded by this gene is a component of the multiprotein assembly that is required for creation of kinetochore-microtubule attachments and chromosome segregation. The encoded protein functions as a scaffold for proteins that influence the spindle assembly checkpoint during the eukaryotic cell cycle and it interacts with at least five different kinetochore proteins and two checkpoint kinases. In adults, this gene is predominantly expressed in normal testes, various cancer cell lines and primary tumors from other tissues and is ubiquitously expressed in fetal tissues. This gene was originally identified as a fusion partner with the mixed-lineage leukemia (MLL) gene in t(11\;15)(q23\;q14). Mutations in this gene cause autosomal recessive primary microcephaly-4 (MCPH4). Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described but their biological validity has not been confirmed. [provided by RefSeq, Jan 2013].

recommended

CASC5 Protein (AA 3-98) (GST tag) (ABIN1348085)

CASC5 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

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recommended

CASC5 Protein (AA 1-1612) (His tag) (ABIN3135614)

Crystallography grade CASC5 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

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recommended

CASC5 Protein (AA 1-230) (His tag) (ABIN7420573)

CASC5 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % WB, SDS, Imm, PC

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CASC5 Proteins by Grade

Find CASC5 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

CASC5 Proteins by Origin

Find CASC5 Proteins for a variety of species such as anti-Mouse CASC5, anti-Human CASC5. The species listed below are among those available. Click on a link to go to the corresponding products.

CASC5 Proteins by Source

Here you will find CASC5 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

CASC5 Proteins by Protein Type

Here you can find CASC5 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

CASC5 Proteins by Application

Find CASC5 Proteins validated for a specific application such as WB, SDS, ELISA, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular CASC5 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

CASC5 Protein (AA 3-98) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1348085

Quantity 10 μg

Datasheet Datasheet

CASC5 Protein (AA 1-1612) (His tag)

Reactivity Mouse

Source Insect Cells

Validations

Cat. No. ABIN3135614

Quantity 1 mg

Datasheet Datasheet

CASC5 Protein (AA 1-230) (His tag)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7420573

Quantity 100 μg

Datasheet Datasheet

CASC5 Protein (AA 1-277) (His tag,GST tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7423420

Quantity 100 μg

Datasheet Datasheet

CASC5 Protein

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN6119589

Quantity 100 μg

Datasheet Datasheet

Aliases for CASC5 Proteins

kinetochore scaffold 1 (KNL1) Proteins
kinetochore scaffold 1 (Knl1) Proteins
Kinetochore null protein 1 (knl-1) Proteins
2310043D08Rik Proteins
5730505K17Rik Proteins
AF15Q14 Proteins
CT29 Proteins
D40 Proteins
hKNL-1 Proteins
hSpc105 Proteins
KNL1 Proteins
PPP1R55 Proteins
Rad51 Proteins
Spc7 Proteins

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CASC5 Proteins by Grade

CASC5 Proteins by Origin

CASC5 Proteins by Source

CASC5 Proteins by Protein Type

CASC5 Proteins by Application

Popular CASC5 Proteins

Aliases for CASC5 Proteins

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