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anti-Human CXCL14 Antibodies:
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Cow (Bovine) Polyclonal CXCL14 Primary Antibody for IHC, WB - ABIN2792192
Takahashi, Takahashi, Takahashi, Zolotaryov, Hong, Iida, Okimura, Kaji, Chihara: CXCL14 enhances insulin-dependent glucose uptake in adipocytes and is related to high-fat diet-induced obesity. in Biochemical and biophysical research communications 2007
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Cow (Bovine) Polyclonal CXCL14 Primary Antibody for ELISA - ABIN4265370
Siezen, Bont, Hodemaekers, Ermers, Doornbos, Vant Slot, Wijmenga, Houwelingen, Kimpen, Kimman, Hoebee, Janssen: Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes. in The Pediatric infectious disease journal 2009
CXCL14 peptides could have roles as anti-inflammatory agents and anti-microbials; the analog of CXCL1459-75 (named CXCL14-C17) corresponds to the C-terminal alpha-helix of CXCL14
Therefore, Porphyromonas gingivalis not only directly stimulates CXCL14 expression via PAR-3 but also promotes its expression by antagonising EGF signalling.
These findings suggest a possibility that cells at the sites of MELF pattern had acquired increased invasiveness through the function of the CXCL14-CXCR4 and CXCL12-CXCR4 axes.
These findings indicate that CXCL14 is a critical immunomodulator involved in the stroke-induced inflammatory reaction.
These results suggest that that CXCL14 is a positive allosteric modulator of CXCR4 via CXCL12 that enhances the potency of CXCR4 ligands.
High CXCL14 expression is associated with metastatic progression of Ovarian Cancer.
These results suggest that CXCL14 downregulation by human papillomaviruses plays an important role in suppression of antitumor immune responses.
Platelets are a relevant source of CXCL14. Platelet-derived CXCL14 at the site of vascular lesions might play an important role in vascular repair/regeneration.
Epithelial CXCL14 expression is significantly associated with ERalpha positivity and low proliferation, whereas stromal CXCL14 expression is not linked to any of the established clinicopathological parameters, subtypes of breast cancer or tumour stroma abundance.
Elevated expression of CXCL14 in osteosarcoma tissues correlated with poor prognosis of the osteosarcoma patients.
Data indicate that CXC chemokine CXCL14, CXC chemokine receptor CXCR7 and the ratio between CXC chemokine receptor CXCR4-2 and CXCR4-1 could predict diseae free survival in Ewing sarcoma patients.
Elevated S100A6 enhances tumorigenesis and suppresses CXCL14-induced apoptosis in clear cell renal cell carcinoma.
three of these five genes (CXCL14, ITGAX, and LPCAT2) harbored polymorphisms associated with aggressive disease development in a human GWAS cohort consisting of 1,172 prostate cancer patients.
Prometastatic effects of IRX1 were mediated by upregulation of CXCL14/NF-kappaB signaling.
CXCL14 overexpression influences proliferation and changes in cell cycle distributions of HT29 colorectal carcinoma cells.
Data indicate that site-specific CpG methylation in the CXC chemokine CXCL14 promoter is associated with altered expression.
essential CXCL12-operated functions of CXCR4 are insensitive to CXCL14
CXCL14 displays antimicrobial activity against E. coli and S. aureus.
Genetic or pharmacologic inhibition of NOS1 reduced the growth of CXCL14-expressing fibroblasts.
CXCL14 inhibits colorectal cancer migration, invasion, and epithelial-to-mesenchymal transition (EMT) by suppressing NF-kappaB signaling.
CXCL14 is expressed by islet delta-cells where it may have paracrine effects to inhibit insulin secretion in a CXCR4/CXCR7-independent manner through reductions in beta-cell ATP levels.
CXCL14 Tg mice showed a suppressed rate of carcinogenesis, decreased tumour volume, and reduced pulmonary metastasis, as well as an increased survival rate of mice following tumour cell injection.
CXCL14 does not seem to play a pivotal role during influenza and Escherichia coli infections of the lung.
CXCL14 was able to promote bone metastasis through enhancement of cancer cell tropism to the bone and/or recruitment of bone marrow cells around metastatic cancer cells.
The unique and non-overlapping patterns of CXCL12 and CXCL14 expression in ocular tissues suggest that these two chemokines may interact and have important functions in cell proliferation, differentiation and migration during eye development.
In conclusion, our results suggested the important function of Cxcl14 in uNK cells and the proper level of Cxcl14 protein were required to recruit NK cells to pregnant uterus.
the transient expression of CXCL14 by Purkinje cells in the developing cerebellum, suggesting that it must be involved in the postnatal maturation of the cerebellum
CXCL14 may play an important role in central nervous system regulation of feeding behavior
Study identifies CXCL14 as a novel marker of tendon connective tissue.
Murine CXCL14 is dispensable for the homeostatic recruitment of antigen-presenting cells toward the periphery and for LC functionality.
CXCL14 is a critical chemoattractant of white adipose tissue macrophages and a novel regulator of glucose metabolism that functions mainly in skeletal muscle.
These results suggest that CXCL14 plays a causal role in high-fat diet-induced obesity.
Data suggest that despite the structural homology and similarity in tissue distribution of human and murine CXCL14, distinct differences point to diverse, species-specific needs for CXCL14 in epithelial immunity.
findings demonstrate that early overexpression of PMP22 in a mouse model of Charcot-Marie-Tooth disease type 1A results in a strong up-regulation of CXCL14 which seems to play a novel regulatory role in Schwann cell differentiation
-A-induced migration depends on the selective and polarized release of 2 chemokines, namely CXC chemokine ligands 12 and 14
CXCL14 is an important paracrine/autocrine modulator regulating trophoblast outgrowth at the maternal-fetal interface during the process of pregnancy establishment.
These data indicate the possibility that BRAK expression inhibits tumor cell establishment by regulating interactions between tumor stem cells and NK cells and/or suppressing formation of tumor microvessels.
This gene belongs to the cytokine gene family which encode secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC (Cys-X-Cys) subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. It has been implicated that this cytokine is involved in the homeostasis of monocyte-derived macrophages rather than in inflammation.
C-X-C motif chemokine 14
, CXC chemokine in breast and kidney
, MIP-2 gamma
, breast and kidney
, chemokine BRAK
, small inducible cytokine subfamily B (Cys-X-Cys), member 14 (BRAK)
, small-inducible cytokine B14
, tumor-suppressing chemokine
, B-cell and monocyte-activating chemokine
, kidney-expressed chemokine CXC
, musculus CXC chemokine MIP-2gamma
, small inducible cytokine subfamily B (Cys-X-Cys), member 14
, member a
, small inducible cytokine subfamily b (Cys-X-Cys), member a
, jun-suppressed chemokine
, chemokine (C-X-C motif) ligand 14
, small inducible cytokine B14