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Human Monoclonal alpha Fetoprotein Primary Antibody for CyTOF, FACS - ABIN4900677
Jeon, Lim, Kim, Thuan, Park, Lim, Choi, Lee, Kim, Lee, Cho: Differentiation and transplantation of functional pancreatic beta cells generated from induced pluripotent stem cells derived from a type 1 diabetes mouse model. in Stem cells and development 2012
Show all 18 Pubmed References
Human Polyclonal alpha Fetoprotein Primary Antibody for IHC (p), WB - ABIN3043730
Yang, Gu, Zheng, Li, Lian, Miao, Jiang, Wei: RPB5-mediating protein is required for the proliferation of hepatocellular carcinoma cells. in The Journal of biological chemistry 2011
Show all 8 Pubmed References
Human Monoclonal alpha Fetoprotein Primary Antibody for IHC (p) - ABIN3043622
Qin, Hua, Shuang, Wang, Cui: Effects of matrine on HepG2 cell proliferation and expression of tumor relevant proteins in vitro. in Pharmaceutical biology 2010
Show all 8 Pubmed References
Human Monoclonal alpha Fetoprotein Primary Antibody for IF (p), IHC (p) - ABIN722901
Zong, Wu, Wang, Ju, Yan: Chemiluminescence imaging immunoassay of multiple tumor markers for cancer screening. in Analytical chemistry 2012
Show all 6 Pubmed References
Human Monoclonal alpha Fetoprotein Primary Antibody for CyTOF, FACS - ABIN4900678
Tramontini, Huber, Liu-Bryan, Terkeltaub, Kilgore: Central role of complement membrane attack complex in monosodium urate crystal-induced neutrophilic rabbit knee synovitis. in Arthritis and rheumatism 2004
Show all 6 Pubmed References
Human Monoclonal alpha Fetoprotein Primary Antibody for IF (p), IHC (p) - ABIN722916
Lin, Mei, Liu, Jin, Wang, Wang: Cascade signal amplification for electrochemical immunosensing by integrating biobarcode probes, surface-initiated enzymatic polymerization and silver nanoparticle deposition. in Biosensors & bioelectronics 2014
Show all 3 Pubmed References
Human Monoclonal alpha Fetoprotein Primary Antibody for IF, IP - ABIN559807
Ramón-Azcón, Yasukawa, Mizutani: Immunodevice for simultaneous detection of two relevant tumor markers based on separation of different microparticles by dielectrophoresis. in Biosensors & bioelectronics 2011
Show all 2 Pubmed References
Human Monoclonal alpha Fetoprotein Primary Antibody for ELISA, WB - ABIN969492
Liu, Yu, Sy, Redman, Lipmann: Tyrosine sulfation of proteins from the human hepatoma cell line HepG2. in Proceedings of the National Academy of Sciences of the United States of America 1985
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Human Monoclonal alpha Fetoprotein Primary Antibody for IP, ELISA - ABIN93889
Cermák, Símová, Pintzas, Horejsí, Andera: Molecular mechanisms involved in CD43-mediated apoptosis of TF-1 cells. Roles of transcription Daxx expression, and adhesion molecules. in The Journal of biological chemistry 2002
Human Monoclonal alpha Fetoprotein Primary Antibody for IF (p) - ABIN722904
Liu, Zhang, Lu, Li: 3-D microarray and its microfabrication-free fluidic immunoassay device. in Analytica chimica acta 2015
High-levels of PIVKA-II in at-risk patients is an indicator of hepatocellular carcinoma (HCC (show FAM126A Antibodies))development in two-year time. CONCLUSIONS: Our data showed that PIVKA-II effectively increases the detection rate of HCC (show FAM126A Antibodies) was a valid complement to AFP and image examination in HCC (show FAM126A Antibodies) surveillance
Unspecific AFP elevations occur in about 2% of pure testicular seminoma patients.
HCC (show FAM126A Antibodies) [hepatocellular carcinoma] patients who are sero-positive for DCP (show ACE Antibodies) [Des (show DES Antibodies)-gamma-carboxyprothrombin] and sero-negative for AFP[Alpha-fetoprotein] have significantly higher levels of serum ALT[alanine aminotransferase (show ALT Antibodies)]; serum ALT levels may be of diagnostic importance in AFP-negative, HBV-related HCC (show FAM126A Antibodies) [hepatitis B virus-related hepatocellular carcinoma] patients.
Higher baseline serum AFP levels independently predicted a lower sustained viral response to antivirals among patients with chronic hepatitis C.
Computer modeling shows the identification of potential binding sites of lysophospholipids (LP) receptors on the AFP third domain receptor binding fragment. AFP might bind not only to the LPL (show LCP1 Antibodies) receptors, but also to LPLs themselves since AFP binds medium and long chain fatty acids. It is proposed that some of the activities ascribed to AFP might be due in part to the presence of bound LPLs and/or their receptors. [review]
AFP may be an important molecule acting against paclitaxel-inhibited proliferation and induced apoptosis in hepatocellular carcinoma cells via repressing the activity of caspase-3 (show CASP3 Antibodies) and stimulating the expression of Ras and Survivin (show BIRC5 Antibodies).
PIVKA II, when combined with AFP, may be considered as a screening test for hepatocellular carcinoma due to its high negative predictive value.
Identification of the distinct impact of circulating tumor derived AFP on NK-cell function and viability may be crucial to developing a strategy to ameliorate hepatocellular carcinoma patient NK-cell functional deficits.
The detection of ALT, AFP, AFP-L3, and GP73 (show GOLM1 Antibodies) has a certain guiding significance to predict the risk of hepatocellular carcinoma in hepatic cirrhosis patients
Antibody therapy targeted at AFP-producing tumor cells showed an inhibitory effect on the PI3K/AKT pathway via the liberation, restoration and functional stabilization of PTEN. PTEN simultaneously induced both P53 activation and intracellular translocation of GLUT1, since these are closely associated with PTEN.
endogenous AFP expression in the perinatal liver is reduced in the absence of beta-catenin (show CTNNB1 Antibodies), suggesting that beta-catenin (show CTNNB1 Antibodies) regulates AFP during liver development.
Findings indicate that AFP expressed under experimental cryptorchid conditions plays a role as a regulatory factor in spermatogenesis and in hepatic generation.
AFP mRNA and VEGF-C (show VEGFC Antibodies) mRNA in peripheral blood were significantly correlated with recurrence and metastasis of hepatocellular carcinoma.
A DEHP treatment-induced phenotype was identified with lack of glycogen (show GYS1 Antibodies) accumula-tion and intracytoplasmic localization of beta-catenin (show CTNNB1 Antibodies) which was associated with increased AFP gene expression.
The deficits observed in parental behavior of AFP knockout females could not be explained by any changes in olfactory function, novelty recognition or anxiety
Foxa1 (show FOXA1 Antibodies) acts as a pioneer transcription factor in de novo activation of Afp, by exploiting a lack of methylation at juxtaposed transposed elements
The level of AFP mRNA in peripheral blood may indicate recurrence and/or metastasis after curative resection of hepatocellular carcinoma.
AFP affects cell proliferation by binding its receptor to trigger the signal transduction pathway of cAMP-PKA and alter the expression of K- ras (show HRAS Antibodies) p21 (show D4S234E Antibodies) genes
A murine Nkx2.8 (show NKX2-6 Antibodies) was isolated from the Hepal-6 cell line and showed oligonucleotide binding competitive with fetoprotein transcription factor (show NR5A2 Antibodies).
The mouse alpha-fetoprotein promoter is repressed in HepG2 hepatoma cells by hepatocyte nuclear factor-3 (show FOXA1 Antibodies)
Equine alpha-fetoprotein seems to be an important indicator of fetal well-being in horses.
This study confirmed that alpha-fetoprotein (AFP) is present in the fetal fluids of mares during the third trimester of pregnancy; experimentally induced placentitis was associated with an elevation in maternal plasma concentrations of AFP.
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
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