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The amount of dopamine d1 receptor, dopamine D2 receptor (show DRD2 Proteins), and follicle stimulating hormone receptor (FSHr (show FSHR Proteins)) mRNA were quantified in ovarian tissues in anestrous and mares expressing estrus during the breeding season are reported.
study to identify putative genetic factors in genes of serotonergic and dopaminergic systems modulating the level of manifestation of depressive symptoms in children; a significant interaction effect was detected between rs1039089 in conjunction with rs877138 located upstream of DRD1 and DRD2 (show DRD2 Proteins) genes respectively
DRD1, DRD2 and DRD3 may not be the susceptibility genes for schizophrenia in the Chinese Han population.
Signaling of dopamine receptor D1 is regulated by VPS35 (show vps35 Proteins).
The Parkinson's disease-associated LRRK2 mutant G2019S impairs DRD1 internalization, leading to an alteration in signal transduction. The mutant forms of LRRK2 also affect receptor turnover by decreasing the rate of DRD2 (show DRD2 Proteins) trafficking from the Golgi complex to the cell membrane.
Here, using PET with [(11)C]raclopride, we identified in the AKT1 (show AKT1 Proteins) gene a new variable number tandem repeat (VNTR) marker associated with baseline striatal dopamine D2/D3 receptor (show DRD3 Proteins) availability and with methylphenidate-induced striatal dopamine increases in healthy volunteers.
We explore the role of mothers' executive function in mediating the relation between oxytocin and dopamine gene variants and maternal responsiveness and examined single nucleotide polymorphisms (SNPs) related to the dopamine system DRD1 rs686, DRD1 rs265976,. Dopamine SNPs were not associated with any measure of executive function or parenting (all P > 0.05).
DRD1 gene polymorphisms are related to heroin dependence in a Chinese Han population and may be informative for future genetic or biological studies on heroin dependence.
Polymorphic mutations in the D2 receptor (show DRD2 Proteins) play a role in dimmer formation with the dopamine D1 receptor.
Parkinson's patients carrying allele T at DRD1C62T had an increased risk of visual hallucinations (VHs), expressed as OR (95 % CI, p value), of 10.7 (2.9-40, p = 0.0001). Moreover, patients with DRD1-48 GG and 62TT genotype displayed shorter time to VHs, whereas a longer time to VHs was found in subjects carrying the DRD4 (show DRD4 Proteins) CG alleles
DRD1 gene expression reduction in breast cancer patients after spiritual intervention
The results suggest that endocytosis of beta(1)-adrenoceptor (show ADRB1 Proteins) in renal proximal tubular cells is an important step in signal generation, while endocytosis of proximal tubular D1 receptor is not.
There were significant differences in the allelic frequencies among Bos taurus and Bos indicus breeds of different temperament for the DRD1, DRD4 (show DRD4 Proteins), and DRD5 (show DRD5 Proteins) markers.
Dopamine D1 receptor play role in memory consolidation.
these data provide evidence that functional D1/D5 receptors are expressed in the internal globus pallidus and the substantia nigra pars (show EPRS Proteins) reticulata in both normal and parkinsonian states in monkeys
Study indicates that dopamine D1Rs are expressed by different classes of interneurons in all layers examined and not by pyramidal cells, suggesting that hippocampus CA1 (show CA1 Proteins) D1R mostly acts via modulation of GABAergic interneurons.
Study shows that dopamine and the dopamine receptor D1 are associated with decreased social interaction
Dopamine D1 receptor-expressing cells in the hippocampus contribute to cocaine conditioned place preference extinction.
Localization of the dopamine receptors of types 1 and 2 on the bodies of POMC (show POMC Proteins)-expressing neurons of the arcuate nucleus of the hypothalamus in mice and rats.
Synergistically acting agonists and antagonists of G protein-coupled receptors prevent photoreceptor cell degeneration
Results show that deleted in colorectal cancer (show DCC Proteins) receptors contribute to the dynamic refinement of dopamine D1 and D2 receptor (show DRD2 Proteins) expression in striatal regions across adolescence. The age-dependent expression of dopamine receptor in C57BL6 mice shows marked differences from previous characterizations in rats.
Salicylate-induced tinnitus may be associated with increased mRNA expression of the DR1A gene - but with decreased mRNA expression of the CR1 (show TDGF1 Proteins) gene - in the cochlea and in many tinnitus-related brain areas.
dopamine is coupled to AMPK (show PRKAA1 Proteins) activation, which provides a substantial anti-inflammatory and bioenergetic advantage and reduces the severity of endotoxin-induced acute lung injury.
The result of this study showed that Dopamine D1 receptor expression is bipolar cell type-specific in the mouse retina.
This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene.
dopamine receptor, D1
, D(1A) dopamine receptor
, dopamine receptor D1
, dopamine D1-like receptor
, CD167 antigen-like family member A
, cell adhesion kinase
, discoidin domain receptor family, member 1
, discoidin receptor tyrosine kinase
, epithelial discoidin domain receptor 1
, epithelial discoidin domain-containing receptor 1
, neurotrophic tyrosine kinase receptor type 4
, protein-tyrosine kinase 3
, protein-tyrosine kinase PTK-3
, tyrosine kinase DDR
, tyrosine-protein kinase CAK
, dopamine D1 receptor
, Dopamine-1A receptor
, dopamine receptor 1A
, dopamine receptor D1A
, D1a dopamine receptor
, dopamine D1A receptor
, Dopamine D1 receptor
, D1 receptor
, D1A dopamine receptor
, G protein-coupled receptor DRD1