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There were significant differences in the allelic frequencies among Bos taurus and Bos indicus breeds of different temperament for the DRD1, DRD4 (show DRD4 Proteins), and DRD5 (show DRD5 Proteins) markers.
Two SUMO modification sites existed in dopamine receptor D1, the phosphorylation of which, due to SUMO modification, can interact with PP2A (show PPP2R4 Proteins), leading to the inhibition of D1 de-phosphorylation and normal function.
Nucleus accumbens dopamine-dopamine receptor signaling regulates sexual preference for females in male mice via Trpc2 (show TRPC2 Proteins).
childhood urbanicity and variation in dopamine genes COMT (show COMT Proteins), DRD1 and DRD2 (show DRD2 Proteins) alters adult prefrontal function as measured by fMRI
DR1 (show DR1 Proteins) induces osteosarcoma cell apoptosis via changes to the MAPK (show MAPK1 Proteins) pathway
Synonymous SNPs (rs1799914 and rs4867798) of the DRD1 gene were associated with Essential Hypertension in Hani nationality However, none SNPs of DRD1 and DRD3 of best models showed association with Essential Hypertension in Han and Yi nationality.
study to identify putative genetic factors in genes of serotonergic and dopaminergic systems modulating the level of manifestation of depressive symptoms in children; a significant interaction effect was detected between rs1039089 in conjunction with rs877138 located upstream of DRD1 and DRD2 (show DRD2 Proteins) genes respectively
DRD1, DRD2 and DRD3 may not be the susceptibility genes for schizophrenia in the Chinese Han population.
Signaling of dopamine receptor D1 is regulated by VPS35 (show vps35 Proteins).
The Parkinson's disease-associated LRRK2 mutant G2019S impairs DRD1 internalization, leading to an alteration in signal transduction. The mutant forms of LRRK2 also affect receptor turnover by decreasing the rate of DRD2 (show DRD2 Proteins) trafficking from the Golgi complex to the cell membrane.
Here, using PET with [(11)C]raclopride, we identified in the AKT1 (show AKT1 Proteins) gene a new variable number tandem repeat (VNTR) marker associated with baseline striatal dopamine D2/D3 receptor (show DRD3 Proteins) availability and with methylphenidate-induced striatal dopamine increases in healthy volunteers.
The amount of dopamine d1 receptor, dopamine D2 receptor (show DRD2 Proteins), and follicle stimulating hormone receptor (FSHr (show FSHR Proteins)) mRNA were quantified in ovarian tissues in anestrous and mares expressing estrus during the breeding season are reported.
The results suggest that endocytosis of beta(1)-adrenoceptor (show ADRB1 Proteins) in renal proximal tubular cells is an important step in signal generation, while endocytosis of proximal tubular D1 receptor is not.
these data provide evidence that functional D1/D5 receptors are expressed in the internal globus pallidus and the substantia nigra pars (show EPRS Proteins) reticulata in both normal and parkinsonian states in monkeys
Heroin-induced impulsive behavior in the 5-choice serial reaction time task is oppositely modulated by D1 and D3 receptor (show DRD3 Proteins) activation.
This study explored the spatial distribution of D1 medium-sized spiny neurons across the rostral-caudal axis of the striatum using D1-tdTomato double transgenic mice.
Wiskott-Aldrich syndrome protein family (WAVE1 (show WASF1 Proteins)) knocked out (KO) in neurons expressing the D1 dopamine receptor (D1-KO) exhibited a significant decrease in place preference associated with cocaine.
Study indicates that dopamine D1Rs are expressed by different classes of interneurons in all layers examined and not by pyramidal cells, suggesting that hippocampus CA1 (show CA1 Proteins) D1R mostly acts via modulation of GABAergic interneurons.
Study shows that dopamine and the dopamine receptor D1 are associated with decreased social interaction
Dopamine D1 receptor-expressing cells in the hippocampus contribute to cocaine conditioned place preference extinction.
Localization of the dopamine receptors of types 1 and 2 on the bodies of POMC (show POMC Proteins)-expressing neurons of the arcuate nucleus of the hypothalamus in mice and rats.
Synergistically acting agonists and antagonists of G protein-coupled receptors prevent photoreceptor cell degeneration
Results show that deleted in colorectal cancer (show DCC Proteins) receptors contribute to the dynamic refinement of dopamine D1 and D2 receptor (show DRD2 Proteins) expression in striatal regions across adolescence. The age-dependent expression of dopamine receptor in C57BL6 mice shows marked differences from previous characterizations in rats.
Salicylate-induced tinnitus may be associated with increased mRNA expression of the DR1A gene - but with decreased mRNA expression of the CR1 (show TDGF1 Proteins) gene - in the cochlea and in many tinnitus-related brain areas.
Dopamine D1 receptor play role in memory consolidation.
This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene.
dopamine receptor, D1
, D(1A) dopamine receptor
, dopamine D1A receptor
, D1a dopamine receptor
, dopamine D1 receptor
, dopamine receptor D1
, dopamine D1-like receptor
, Dopamine D1 receptor
, D1 receptor
, D1A dopamine receptor
, G protein-coupled receptor DRD1
, Dopamine-1A receptor
, dopamine receptor 1A
, dopamine receptor D1A