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anti-Human DRD4 Antibodies:
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Human Monoclonal DRD4 Primary Antibody for WB - ABIN1882234
Zeng, Ye, Lu, Chua, Tan, Zhong: Chiral Brønsted acid catalyzed enantioselective addition of alpha-isocyanoacetamides to aldehydes. in Organic letters 2010
Show all 4 Pubmed References
Human Monoclonal DRD4 Primary Antibody for WB - ABIN1882235
Lai, Zhu, Huo, Sun, Yu, Wang, Chai, Li: Association study of polymorphisms in the promoter region of DRD4 with schizophrenia, depression, and heroin addiction. in Brain research 2010
Show all 4 Pubmed References
Human Polyclonal DRD4 Primary Antibody for FACS, IHC (p) - ABIN652706
Ma, Thapa, Morris, Michalakis, Biel, Frank, Bebak, Ding: Loss of cone cyclic nucleotide-gated channel leads to alterations in light response modulating system and cellular stress response pathways: a gene expression profiling study. in Human molecular genetics 2013
Authors examined the possible association between DRD4 allelic variation and three measures of juvenile behavior. Five different DRD4 alleles (5R, 5.5R, 6R, 6.5R, and 7R) were identified in the subject population.
genetic association studies in population of young adults in Columbia: Data suggest that genetic polymorphisms in DRD4 and SLC6A3 (show SLC6A3 Antibodies) are associated with overweight/obesity in the population studied; DRD4 4/4 genotype is associated with lower BMI and SLC6A3 (show SLC6A3 Antibodies) 10/10 genotype is associated with higher BMI. (DRD4 = dopamine receptor D4; SLC6A3 (show SLC6A3 Antibodies) = solute carrier family 6 member 3 (show SLC6A3 Antibodies))
These data suggest that the DRD4 polymorphisms are associated with localized brain activity and specific functional connections, including abnormality in the frontal-striatal-cerebellar loop.
Results suggest that alterations in the glutamate (show GRIN1 Antibodies) and dopamine system (GRIN2B (show GRIN2B Antibodies) and DRD4) in attention-deficit/hyperactivity disorder may contribute to abnormalities in local functional connectivity and its dynamic repertoire in the superior parietal area, and these abnormalities would be related to dysfunction in sustained and divided attention.
There is significant interaction effects of the GIT1 and DRD4 gene variants on impulsivity in Attention Deficit Hyperactivity Disorder.
The DRD4 and 5HTR2A genes are co-expressed in Peripheral Blood Mononuclear Cells during antipsychotic administration. Despite a correlation between the studied biogenic amine indicators and the psychopathological status of patients, reliable biomarkers of treatment response could not be determined.
heterozygotes at the DRD4 locus are more risk averse than either homozygotes
We report an interaction between birth weight status and DRD4 gene in predicting respiratory sinus arrhythmia, such that DRD4 long carriers had the highest and lowest resting respiratory sinus arrhythmia depending on whether they were born normal or extremely low birth weight, respectively.
This study adds to the growing evidence on the association of single- and multiple-risk variants in DRD3 (show DRD3 Antibodies), DRD4, and FEV (show FEV Antibodies) with aggressive behavior in Chinese adolescents.
DRD4 haplotypes may play a role in general psychopathology in patients with eating disorders
Results indicated that DRD4 L carriers with a sexual trauma history reported significantly more severe suicidal ideation than DRD4S homozygotes.
Results indicate that the full rescue of impaired LTP (show SCP2 Antibodies) in aging is achieved by the selective D4R activation.
over-suppression of NMDAR (show GRIN1 Antibodies) function may underlie the role of hD4.7 in attention deficit hyperactivity disorder
Synergistically acting agonists and antagonists of G protein-coupled receptors prevent photoreceptor cell degeneration
The G-protein coupled receptor, DRD4, requires ARR1 and ARR4 for desensitization and internalization.
This study demonstrated that dopamine D4 receptor gene has an important role in increased exploratory and anxiolytic behavior only in males and these behaviors were positively correlated with increased alcohol consumption.
Contrast sensitivity is reduced in Drd4-/- mice.
dopaminergic modulation of early long-term potentiation in stratum oriens occurs through NMDA receptors containing NR2B (show GRIN2B Antibodies) subunits via D4Rs
Data demonstrate that stimulating the dopamine Dreceptor is essential in maintaining the normal rhythmic production of adenylyl cyclase 1 (show ADCY1 Antibodies) from transcript to enzyme activity.
This study demonistrated that the dopamine D4 receptor is the role of attention.
The result of this study demonistrated that the dopamine drd4 receptor appears to be important for specific exploration.
This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats\; the sequence shown contains four repeats.
dopamine D4b receptor
, dopamine receptor D4
, D(2C) dopamine receptor
, D(4) dopamine receptor
, dopamine D4 receptor
, seven transmembrane helix receptor
, d(2C) dopamine receptor
, dopamine receptor 4