Protein Summary

The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported.

Alternative names and synonyms associated with TNFSF14

• TNF superfamily member 14 (TNFSF14) antibody
• TNF superfamily member 14 (Tnfsf14) antibody
• tumor necrosis factor (ligand) superfamily, member 14 (Tnfsf14) antibody

• CD258 antibody
• HVEM-L antibody
• HVEML antibody
• LIGHT antibody
• LTg antibody
• Show all synonym aliases
• Ly113 antibody
• TNFSF14 antibody
• TR2 antibody

Protein level used designations for TNFSF14

tumor necrosis factor ligand superfamily, member 14 , tumor necrosis factor (ligand) superfamily, member 14 , delta transmembrane LIGHT , herpes virus entry mediator ligand , herpesvirus entry mediator A , herpesvirus entry mediator ligand , herpesvirus entry mediator-ligand , ligand for herpesvirus entry mediator , tumor necrosis factor ligand superfamily member 14 , tumor necrosis factor receptor-like 2 , tumor necrosis factor superfamily member LIGHT , tumor necrosis factor superfamily member 14 , tumor necrosis factor superfamily, member 14