Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species and application
anti-Human F2RL3 Antibodies:
anti-Mouse (Murine) F2RL3 Antibodies:
anti-Rat (Rattus) F2RL3 Antibodies:
Go to our pre-filtered search.
Human Polyclonal F2RL3 Primary Antibody for WB - ABIN2801951
Kahn, Hammes, Botka, Coughlin: Gene and locus structure and chromosomal localization of the protease-activated receptor gene family. in The Journal of biological chemistry 1998
Show all 4 Pubmed References
Human Monoclonal F2RL3 Primary Antibody for IHC, ELISA - ABIN1724706
Xie, Guo: Par-4 inhibits choline uptake by interacting with CHT1 and reducing its incorporation on the plasma membrane. in The Journal of biological chemistry 2004
Show all 4 Pubmed References
Human Monoclonal F2RL3 Primary Antibody for ELISA, WB - ABIN563904
Muehlschlegel, Perry, Liu, Fox, Smith, Lichtner, Collard, Shernan, Hartwig, Body, Hoffmeister: Polymorphism in the protease-activated receptor-4 gene region associates with platelet activation and perioperative myocardial injury. in American journal of hematology 2013
Human Polyclonal F2RL3 Primary Antibody for IF (p), IHC (p) - ABIN673224
Oláh, Kálmán, Tóth, Zvara, Sántha, Ivitz, Janka, Pákáski: Proteomic Analysis of Cerebrospinal Fluid in Alzheimer's Disease: Wanted Dead or Alive. in Journal of Alzheimer's disease : JAD 2014
PAR4 (show PAWR Antibodies) is required for platelet procoagulant function during thrombus formation in human blood
Prospective study demonstrated that AHRR (show CYP1A1 Antibodies) and F2RL3 methylation levels had inverse relationships with self-reported smoking status and accurately discriminated for both current- and former- smoking. Moreover, methylation markers distinguished former smokers from never-smokers with high accuracy and significantly associated with an increased risk of lung cancer.
F2RL3 variants have the potential to markedly alter platelet PAR4 (show PAWR Antibodies) reactivity particularly after exposure to therapeutic PAR1 (show MARK2 Antibodies) antagonists.
these findings are the first to show that internalization of activated PAR4 (show PAWR Antibodies) is linked to proper ERK1/2 (show MAPK1/3 Antibodies) and Akt (show AKT1 Antibodies) activation.
an intracellular PAR4 C-terminal motif that regulates calcium signaling and beta-arrestin interactions, was identified.
the contribution of PAR1 (show MARK2 Antibodies) and PAR4 (show PAWR Antibodies) to thrombin (show F2 Antibodies)-mediated activation of the platelet fibrin receptor (GPIIbIIIa), is reported.
Suppression of PAR4 (show PAWR Antibodies) expression has no significant effect on the proliferation of SW620 cells, but can inhibit the migration of the cells.
Both GPIbalpha (show GP1BA Antibodies) and PAR4 (show PAWR Antibodies) are required for thrombin (show F2 Antibodies)-induced reactive oxygen species formation in human platelets.
Bladder PAR (show JTB Antibodies) activation elicits urothelial MIF (show AMH Antibodies) release and urothelial MIF (show AMH Antibodies) receptor signaling at least partly through CXCR4 (show CXCR4 Antibodies) to result in abdominal hypersensitivity without overt bladder inflammation
protease-activated receptor 4 and Trefoil factor 2 (show TFF2 Antibodies) are expressed in human colorectal cancer
The metabolic effects were associated with activation of the SIRT1 (show SIRT1 Antibodies)-LKB1 (show STK11 Antibodies)-AMPK (show PRKAA1 Antibodies) signalling pathway in adipose tissue and liver.
Treg cells use LKB1 (show STK11 Antibodies) signalling to coordinate their metabolic and immunological homeostasis and to prevent apoptotic and functional exhaustion, thereby orchestrating the balance between immunity and tolerance
renal proximal tubule cell CB1R (show CNR1 Antibodies) contributes to the pathogenesis of obesity-induced renal lipotoxicity and nephropathy by regulating the liver kinase B1 (show STK11 Antibodies)/AMP-activated protein kinase (show PRKAA2 Antibodies) signaling pathway
Results reveal an important role for Lkb1 (show STK11 Antibodies) in regulating cerebellar cortical size and foliation in a Hedgehog (show SHH Antibodies)-independent manner.
beige (show LYST Antibodies) adipocyte renaissance was governed by liver kinase b1 (show STK11 Antibodies) and histone deacetylase 4 (show HDAC5 Antibodies) in white adipocytes.
miR-17-92-dependent tuning of LKB1 (show STK11 Antibodies) levels regulates both the metabolic potential of Myc (show MYC Antibodies)+ lymphomas and tumor growth in vivo.
Findings indicate that the energy-sensing LKB1 (show STK11 Antibodies)-AMPK (show PRKAA1 Antibodies) pathway regulates IGF1 (show IGF1 Antibodies) secretion in mouse primary hepatocytes, which in turn regulates activation of the IGF1R (show IGF1R Antibodies)-PKB (show AKT2 Antibodies) pathway.
These data suggest that nutrient availability dictates the mode of division and that LKB1 (show STK11 Antibodies)-AMPK (show PRKAA1 Antibodies) mediates this nutrient-driven effect on intestinal epithelial stem cell proliferation.
this study identified the molecular mechanism of increased angiogenesis and tumor growth with LKB1 (show STK11 Antibodies) deficiency
These results suggest that although physiologic LKB1 (show STK11 Antibodies) expression exerts a potent pro-survival effect in lymphocytes, LKB1 (show STK11 Antibodies) inactivation nonetheless facilitates transformation of B, but not T, lymphocytes.
Coagulation factor II (thrombin) receptor-like 3 (F2RL3) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL3 is also a member of the protease-activated receptor family. F2RL3 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL3 is activated by thrombin and trypsin.
proteinase-activated receptor 4
, coagulation factor II (thrombin) receptor-like 3
, coagulation factor II (thrombin)
, protease-activated receptor-4
, thrombin receptor-like 3
, coagulation factor II receptor-like 3
, protease-activated receptor 4
, LKB1 short isoform
, liver kinase B1 homolog
, serine/threonine-protein kinase 11
, serine/threonine-protein kinase LKB1
, serine/threonine-protein kinase STK11